Dorsal third ventricular cyst: an entity distinct from holoprosencephaly

1992 ◽  
Vol 77 (4) ◽  
pp. 556-561 ◽  
Author(s):  
Jacob N. Young ◽  
W. Jerry Oakes ◽  
H. Pall Hatten
Keyword(s):  
Infant Development ◽  
Clinical Course ◽  
Careful Study ◽  
Distinct Entity ◽  
Content Type ◽  
Radiological Appearance ◽  
The Third ◽  
Developmental Progress ◽  
Bayley Scales ◽  
Third Ventricular Cyst

✓ The treatment and subsequent developmental progress of six children with dorsal third ventricular cysts are described. This cystic malformation has a radiological appearance which is superficially similar to that of the dorsal cyst of alobar holoprosencephaly, especially when the third ventricular cyst is large. Indeed, previous reports have identified this abnormality as a form of holoprosencephaly. However, careful study reveals that the dorsal third ventricular cyst is a distinct entity both developmentally and clinically. The six patients in this series were effectively treated with shunts, and their subsequent developmental progress was assessed by means of the Prescreening Developmental Questionnaire-Revised as well as the Bayley Scales of Infant Development. The nomenclature and differences between this entity and the holoprosencephalies are reviewed. The authors conclude that dorsal third ventricular cysts have a developmental and clinical course more similar to that of arachnoid cysts than to that of the holoprosencephalies.

Empty sella secondary to suprasellar colloid cyst of foregut (respiratory) origin

1979 ◽  
Vol 51 (1) ◽  
pp. 114-117 ◽  
Author(s):  
Dwight C. Evans ◽  
Martin G. Netsky ◽  
Verne E. Allen ◽  
Vira Kasantikul
Keyword(s):  
Cerebrospinal Fluid ◽  
Third Ventricle ◽  
Sella Turcica ◽  
Colloid Cyst ◽  
Empty Sella ◽  
Content Type ◽  
The Third ◽  
Colloid Cysts ◽  
Third Ventricular Cyst ◽  
Fine Print

✓ An enlarged sella turcica was discovered in a 40-year-old man who had bitemporal headaches. A pneumoencephalograph revealed a third ventricular cyst, dilated lateral ventricles, and an empty sella. The colloid cyst was lined by foregut epithelium, probably originating in the respiratory tract, and dense connective tissue. This case is the first instance of an empty sella associated with a colloid cyst of the third ventricle. It is proposed that enlargement of the mass in the third ventricle caused increased pulsation pressure of the cerebrospinal fluid, and that in the presence of an incompetent diaphragma sellae the subarachnoid space expanded into the sella. The origin of third ventricle cysts is reconsidered. It is concluded that suprasellar colloid cysts may arise from endoderm, ectoderm, neuroepithelium, or a combination of these epithelia.

Diencephalic cysts

1973 ◽  
Vol 38 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Gordon Brocklehurst ◽  
M. Chir.
Keyword(s):  
Corpus Callosum ◽  
Clinical Course ◽  
Third Ventricle ◽  
Embryological Development ◽  
Cystic Dilatation ◽  
Content Type ◽  
The Third ◽  
Radiological Features ◽  
Fine Print

✓ Four cases of extensive cystic dilatation of the third ventricle associated with agenesis of the corpus callosum are described. This condition is termed “diencephalic cyst”; the clinical and radiological features are described. The embryological development of the diencephalon, the telencephalon, and the corpus callosum are described in relation to this malformation. The associated hydrocephalus is also discussed. The treatment and clinical course of the patients is outlined.

Early Developmental Progress of Preterm Twins Discordant for Birthweight and Risk

1988 ◽  
Vol 37 (1) ◽  
pp. 81-87 ◽  
Author(s):  
A. Stauffer ◽  
W.J. Burns ◽  
K.A. Burns ◽  
J. Melamed ◽  
C.E. Herman
Keyword(s):  
High Risk ◽  
Preterm Infants ◽  
Gestational Age ◽  
Infant Development ◽  
Developmental Outcome ◽  
Intelligence Scale ◽  
Developmental Progress ◽  
Iq Scores ◽  
Early Developmental ◽  
Bayley Scales

AbstractStudies of developmental progress in high-risk twins have disparate findings. In this study, we report the outcome of 45 twin pairs born between 26 and 37 weeks gestation, and whose birthweights ranged from 840 to 2000 g. No significant differences were found for weight, risk and birth order. However, earlier preterm infants were found to have significantly lower mental scores on the Bayley Scales of Infant Development at 24 months, and lower IQ scores on the Stanford Binet Intelligence Scale at 36 months. These findings imply that gestational age is a powerful variable in determining developmental outcome.

Monkey brain damage from radiation in the therapeutic range

1976 ◽  
Vol 44 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Hiroyuki Nakagaki ◽  
Gunter Brunhart ◽  
Thomas L. Kemper ◽  
William F. Caveness
Keyword(s):  
Therapeutic Range ◽  
Macaca Mulatta ◽  
Clinical Course ◽  
Vascular Endothelial ◽  
Visual Evoked Response ◽  
Content Type ◽  
Macrophage Response ◽  
The Third ◽  
Endothelial Proliferation ◽  
Delta Activity

✓ Twelve Macaca mulatta monkeys received 200 rads of supervoltage radiation to the whole brain per day, 5 days a week. The course in four monkeys was 4 weeks for a total dose of 4000 rads; in four monkeys, 6 weeks for 6000 rads; and in four monkeys, 8 weeks for 8000 rads. Four unirradiated monkeys served as controls. One from each group, sacrificed at 6 and 12 months from start of irradiation, are reported here. The results from 4000 rads were negligible; those from 8000 rads, profound, with gross brain destruction. The results from 6000 rads, within the therapeutic range, included at 6 months punctate necrotic lesions, 1 mm or less, widely scattered but with a predilection for the forebrain white matter. The reaction to these lesions ranged from an early macrophage response to calcification. Some were accompanied by focal edema. There were occasional examples of vascular endothelial proliferation. In addition, there were patches of dilated capillaries or telangiectasia. Twelve months after 6000 rads there were a few mineralized lesions and innumerable minute deposits of calcium and iron. A more active process was suggested by widely disseminated areas of telangiectasia, 6 to 12 mm in extent. The clinical course from this exposure included papilledema from the third to the sixth month and depressed visual evoked response accompanied by delta activity in the electroencephalogram from the sixth to the twelfth month.

Features of the course and treatment of glaucoma during pregnancy

2020 ◽  
Vol 98 (3) ◽  
pp. 178-184
Author(s):  
T. V. Chernyakova ◽  
A. Yu. Brezhnev ◽  
I. R. Gazizova ◽  
A. V. Kuroyedov ◽  
A. V. Seleznev
Keyword(s):  
Pregnant Women ◽  
Laser Treatment ◽  
Progressive Disease ◽  
Clinical Course ◽  
The Other ◽  
Third Trimester ◽  
The Third ◽  
Chronic Progressive Disease ◽  
Hypotensive Therapy ◽  
Eye Pressure

In the review we have integrated all up-to-date knowledge concerning clinical course and treatment of glaucoma among pregnant women to help specialists choose a proper policy of treatment for such a complicated group of patients. Glaucoma is a chronic progressive disease. It rarely occurs among childbearing aged women. Nevertheless the probability to manage pregnant patients having glaucoma has been recently increasing. The situation is complicated by the fact that there are no recommendations on how to treat glaucoma among pregnant women. As we know, eye pressure is progressively going down from the first to the third trimester, so we often have to correct hypotensive therapy. Besides, it is necessary to take into account the effect of applied medicines on mother health and evaluate possible teratogenic complications for a fetus. The only medicine against glaucoma which belongs to category B according to FDA classification is brimonidine. Medicines of the other groups should be prescribed with care. Laser treatment or surgery may also be a relevant decision when monitoring patients who are planning pregnancy or just bearing a child. Such treatment should be also accompanied by medicines.

Metastatic Colorectal Cancer: Prognostic and Predictive Factors

2020 ◽  
Vol 27 (17) ◽  
pp. 2779-2791 ◽  
Author(s):  
Anna Nappi ◽  
Guglielmo Nasti ◽  
Carmela Romano ◽  
Massimiliano Berretta ◽  
Alessandro Ottaiano
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Predictive Factors ◽  
Cancer Biology ◽  
Clinical Course ◽  
Molecular Signatures ◽  
Biological Drugs ◽  
The Third ◽  
Therapeutic Context ◽  
Prognostic And Predictive Factors

: Colorectal cancer represents the third most frequently occurring cancer worldwide. In the last decade, the survival of patients affected by metastatic colorectal cancer (mCRC) has improved through the introduction of biological drugs. However, in this new and dynamic therapeutic context, research about prognostic and predictive factors is important to guide the oncologists to effective therapies as well as to improve the understanding of colorectal cancer biology. Their identification is an intensive area of research and our future goal will be to depict tumour-specific "molecular signatures" in order to predict the clinical course of the disease and the best treatments. : In this report, we describe clinical, pathological and molecular biomarkers that can play a role as prognostic or predictive factors in mCRC.

scholarly journals Concurrent validity of the Ages and Stages Questionnaire and the Bayley Scales of Infant Development III in China

PLoS ONE ◽  
2019 ◽  
Vol 14 (9) ◽  
pp. e0221675 ◽  
Author(s):  
Ai Yue ◽  
Qi Jiang ◽  
Biaoyue Wang ◽  
Cody Abbey ◽  
Alexis Medina ◽  
...  
Keyword(s):  
Concurrent Validity ◽  
Infant Development ◽  
Ages And Stages Questionnaire ◽  
Bayley Scales

Basal ganglia echogenicity in preterm infants: A case series

2020 ◽  
pp. 1-5
Author(s):  
S. Harvey ◽  
S. Ryan ◽  
A. Tarrant ◽  
M. King ◽  
B. Hayes
Keyword(s):  
Basal Ganglia ◽  
Clinical Course ◽  
Case Series ◽  
Abnormal Development ◽  
Cranial Ultrasound ◽  
Perinatal Factors ◽  
Mri Brain ◽  
Developmental Progress ◽  
Cognitive Delay ◽  
History Of

BACKGROUND: Damage to the basal ganglia and thalamus (BGT) can be caused by multiple perinatal factors and may be associated with movement disorders, cognitive delay and visual difficulties. Changes in BGT structure, seen as echogenicity on ultrasound, are difficult to objectively quantify. The aetiology, clinical relevance and developmental outcomes of BGT echogenicity are poorly understood. We aimed to gain a better understanding of the natural history of BGT echogenicity in a preterm population. METHODS: Retrospective review of clinical course, neuroimaging and development in infants born <32weeks gestation over 5 years with evidence of BGT echogenicity. RESULTS: BGT echogenicity was reported in 18/650 infants (2.7%). Echogenicity appeared at a median of 8 days (2–45 days) and resolved on pre-discharge ultrasound in 50%. Thirteen infants had a term corrected MRI brain with abnormal BGT signal seen in 3 infants (23%). All 3 infants had persisting echogenicity on discharge ultrasound. No infant with echogenicity resolution on ultrasound had changes on term MRI. 14 infants had developmental progress available at 1 year corrected. Abnormal development was reported in four children of whom one had BGT changes on term MRI. Two children with persistent BGT changes but an otherwise normal MRI had reported normal neurodevelopment. CONCLUSION: BGT echogenicity is relatively common on routine ultrasound and resolves in the majority of infants by term corrected. This review suggests that at term corrected, normal cranial ultrasound may obviate the need for MRI where no other concerns exist. BGT echogenicity did not appear to independently influence neurodevelopment.

Sign in / Sign up

Export Citation Format

Share Document