Health-related quality of life after subarachnoid hemorrhage: impacts of bleeding severity, computerized tomography findings, vasospasm, surgery, and neurological grade

2001 ◽  
Vol 94 (2) ◽  
pp. 241-251 ◽  
Author(s):  
Bernd O. Hütter ◽  
Ilonka Kreitschmann-Andermahr ◽  
Joachim M. Gilsbach
Keyword(s):  
Quality Of Life ◽  
Subarachnoid Hemorrhage ◽  
Daily Life ◽  
Health Related Quality ◽  
Content Type ◽  
Related Quality ◽  
Health Related ◽  
Mca Aneurysm ◽  
Fine Print

Object. Based on the results of earlier studies it is agreed that the significance of aneurysm location and surgery for neuropsychological impairments after subarachnoid hemorrhage (SAH) is secondary to the effects of the bleeding itself. Therefore, the present study was performed to evaluate whether bleeding, acute clinical course, and surgery have persistent effects on health-related quality of life (QOL) after SAH. Methods. A series of 116 patients was examined for 4 to 5 years (mean 52.2 months) after aneurysmal SAH by means of a QOL questionnaire. Eighty-six patients (74.1%) had undergone surgery early (≤ 72 hours post-SAH). There were 77 women (66.4%) and 39 men (33.6%) in the study group, and the mean age of the patients was 50.3 ± 13.3 years (range 30–69 years). Patients who had undergone surgery for a left-sided middle cerebral artery (MCA) aneurysm complained of significantly more impairments in social contact, communication, and cognition than those treated for a right-sided MCA aneurysm. No other effects of aneurysm location (including the anterior communicating artery) emerged. Multiple aneurysms, intraoperative aneurysm rupture, and partial resection of the gyrus rectus had no adverse effects on later daily life. Only temporary clipping was associated with increased complaints in some QOL areas. Disturbances of the circulation of cerebrospinal fluid and the presence of intraventricular hemorrhage led to more impairments in daily life. Specific effects of the anatomical pattern of the bleeding could be identified, but no adverse effects of vasospasm were found. Multivariate analyses revealed, in particular, that patient age and admission neurological status (Hunt and Hess grade) are substantial predictors of the psychosocial sequelae of SAH. Conclusions. In contrast to the mild effects of aneurysm surgery, patient's age, initial neurological state on admission, and the bleeding pattern substantially influence late QOL after SAH.

Long-term health-related quality of life outcomes following Jefferson-type burst fractures of the atlas

2005 ◽  
Vol 2 (4) ◽  
pp. 411-417 ◽  
Author(s):  
Marcel F. Dvorak ◽  
Michael G. Johnson ◽  
Michael Boyd ◽  
Garth Johnson ◽  
Brian K. Kwon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
Content Type ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
Fine Print

Object. The primary goal of this study was to describe the long-term health-related quality of life (HRQOL) outcomes in patients who have suffered Jefferson-type fractures. These outcomes were compared with matched normative HRQOL data and with the patient's perceptions of their HRQOL prior to the injury. Variables that potentially influence these HRQOL outcomes were analyzed. No standardized outcome assessments have been published for patients who suffer these fractures; their outcomes have long thought to be excellent following treatment. Determining the optimal surrogate measure to represent preinjury HRQOL in trauma patients is difficult. Methods. A retrospective review, radiographic analysis, and cross-sectional outcome assessment were performed. The Short Form (SF)—36 and the American Academy of Orthopaedic Surgeons/North American Spine Society (AAOS/NASS) outcome instruments were filled out by patients at final follow-up examination (follow-up period 75 months, range 19–198 months) to represent their current status as well as their perceptions of preinjury status. In 34 patients, the SF-36 physical component score and the AAOS/NASS pain values were significantly lower than normative values. There was no significant difference between normative and preinjury values. Spence criteria greater than 7 mm and the presence of associated injuries predicted poorer outcome scores during the follow-up period. Conclusions. Long-term follow-up examination of patients with Jefferson fractures indicated that patients' status does not return to the level of their perceived preinjury health status or that of normative population controls. Those with other injuries and significant osseous displacement (≥ 7 mm total) may experience poorer long-term outcomes. Limitations of the study included a relatively low (60%) response rate and the difficulties of identifying an appropriate baseline outcome in a trauma population with which the follow-up outcomes can be compared.

scholarly journals HG2 Characterizing The Individual Course of Health-Related Quality of Life After Subarachnoid Hemorrhage

2011 ◽  
Vol 14 (7) ◽  
pp. A240
Author(s):  
Y. Winter ◽  
J. Klotsche ◽  
F. Ringel ◽  
A. Spottke ◽  
N. Gharevi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Subarachnoid Hemorrhage ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Individual

Predictors of long-term Health-Related Quality of Life in patients with aneurysmal subarachnoid hemorrhage

2010 ◽  
Vol 30 (2) ◽  
pp. 137-145 ◽  
Author(s):  
P.E.C.A. Passier ◽  
J.M.A. Visser-Meily ◽  
M.J.E. van Zandvoort ◽  
G.J.E. Rinkel ◽  
E. Lindeman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Subarachnoid Hemorrhage ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals PCV48 COST-OF-ILLNESS AND HEALTH-RELATED QUALITY OF LIFE IN SUBARACHNOID HEMORRHAGE: GERMAN LONGITUDINAL STUDY

2010 ◽  
Vol 13 (7) ◽  
pp. A349
Author(s):  
Y Winter ◽  
F Ringel ◽  
A Spottke ◽  
N Gharevi ◽  
T Klockgether ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Longitudinal Study ◽  
Subarachnoid Hemorrhage ◽  
Cost Of Illness ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

A Partial Least-Squares Analysis of Health-Related Quality-of-Life Outcomes After Aneurysmal Subarachnoid Hemorrhage

Neurosurgery ◽  
2015 ◽  
Vol 77 (6) ◽  
pp. 908-915 ◽  
Author(s):  
Julia M. Young ◽  
Benjamin R. Morgan ◽  
Bratislav Mišić ◽  
Tom A. Schweizer ◽  
George M. Ibrahim ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Subarachnoid Hemorrhage ◽  
Least Squares ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Health Related Quality ◽  
Life Outcomes ◽  
Partial Least Squares Analysis ◽  
Related Quality ◽  
Health Related

scholarly journals Influencing of Family Management in Families with Thalassemic Children on Health Related Quality of Life and Family Functioning: SEM approach

2017 ◽  
Vol 16 (1) ◽  
pp. 27-38 ◽  
Author(s):  
Orranuch CHUSRI ◽  
Wannee DEOISRES ◽  
Marcia van RIPER
Keyword(s):  
Quality Of Life ◽  
Family Functioning ◽  
Family Life ◽  
Daily Life ◽  
Negative Influence ◽  
Health Related Quality ◽  
Management Ability ◽  
Related Quality ◽  
Health Related

Purpose: To predicate the way in which families incorporate the work of managing a child with thalassemia within family life and its outcomes. Methods: A correlational design with a structural equation modeling (SEM) approach was used. A total of 309 parents of children with thalassemia from 4 tertiary care hospitals in Thailand completed our questionnaires. Results: Family life difficulties had a negative influence on the child’s health-related quality of life (HRQOL) (b = -2.23, p < 0.05) and family functioning (b = -0.27, p < 0.05), whereas the child’s daily life (b = 5.06, p < 0.05) and condition management ability (b = -1.86, p < 0.05) had a negative influence on the child’s HRQOL. In the final model, 3 variables including the child’s daily life, condition management ability, and family life difficulty could explain 33 % of variance in the child’s HRQOL (R2 = 0.33). This model showed that only family life difficulty could explain 2 % of variance of family functioning (R2 = 0.02). Conclusions: The study suggests that nurses should design interventions to support families in managing their child’s conditions in order to achieve a good child and family outcomes.

scholarly journals Airflow Limitation, Fatigue, and Health-Related Quality of Life in Kidney Transplant Recipients

2021 ◽  
Vol 16 (11) ◽  
pp. 1686-1694
Author(s):  
Tim J. Knobbe ◽  
Daan Kremer ◽  
Michele F. Eisenga ◽  
Marco van Londen ◽  
António W. Gomes-Neto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Kidney Transplant ◽  
Airflow Limitation ◽  
Health Related Quality ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Content Type ◽  
Related Quality ◽  
Health Related

Background and objectivesMany kidney transplant recipients suffer from fatigue and poor health-related quality of life. Airflow limitation may be an underappreciated comorbidity among kidney transplant recipients, which could contribute to fatigue and lower health-related quality of life in this population. In this study, we compared the prevalence of airflow limitation between kidney transplant recipients and healthy controls and investigated associations of airflow limitation with fatigue and health-related quality of life in kidney transplant recipients.Design, setting, participants, & measurementsData from the ongoing TransplantLines Biobank and Cohort study were used. Airflow limitation was defined as forced exhaled volume in 1 second less than the fifth percentile of the general population. Fatigue and health-related quality of life were assessed using checklist individual strength 20 revised (CIS20-R) and Short Form-36 (SF-36) questionnaires.ResultsA total of 539 kidney transplant recipients (58% men; mean age 56±13 years) and 244 healthy controls (45% men; mean age 57±10 years) were included. Prevalence of airflow limitation was higher in kidney transplant recipients than in healthy controls (133 [25%] versus 25 [10%]). In multinomial regression models, airflow limitation was independently associated with fatigue severity (odds ratio moderate fatigue, 1.68; 95% confidence interval, 0.92 to 3.09 and odds ratio severe fatigue, 2.51; 95% confidence interval, 1.39 to 4.55; P=0.007) and lower physical health-related quality of life (−0.11 SDs; 95% confidence interval, −0.19 to −0.02; P=0.01) in kidney transplant recipients. In exploratory mediation analyses, fatigue accounted for 79% of the association of airflow limitation with physical health-related quality of life.ConclusionsAirflow limitation is common among kidney transplant recipients. Its occurrence is associated with more than two times higher risk of severe fatigue, and it is associated with lower physical health-related quality of life. Mediation analyses suggest that airflow limitation causes fatigue, which in turn, decreases physical health-related quality of life.Clinical Trial registry name and registration number:TransplantLines: The Transplantation Biobank, NCT03272841PodcastThis article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2021_11_08_CJN06600521.mp3

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