High-grade primary diffuse leptomeningeal gliomatosis in a child with neurofibromatosis Type 1

2008 ◽  
Vol 2 (6) ◽  
pp. 402-405 ◽  
Author(s):  
James A. J. King ◽  
William Halliday ◽  
James M. Drake
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
High Grade ◽  
First Report ◽  
Primary Diffuse Leptomeningeal Gliomatosis ◽  
Leptomeningeal Gliomatosis ◽  
Primary Glioma

The authors report on a child with known neurofibromatosis Type 1 who developed high-grade diffuse leptomeningeal gliomatosis, without a known primary glioma. To the authors' knowledge, this is the first report of the coexistence of these conditions in a child.

scholarly journals Patients with High-Grade Gliomas and Café-au-Lait Macules: Is Neurofibromatosis Type 1 the Only Diagnosis?

2019 ◽  
Vol 40 (6) ◽  
pp. E30-E31 ◽  
Author(s):  
L. Guerrini-Rousseau ◽  
M. Suerink ◽  
J. Grill ◽  
E. Legius ◽  
K. Wimmer ◽  
...  
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
High Grade ◽  
High Grade Gliomas

scholarly journals Clonal lineage of high grade serous ovarian cancer in a patient with neurofibromatosis type 1

2018 ◽  
Vol 23 ◽  
pp. 41-44 ◽  
Author(s):  
Eric J. Norris ◽  
Wendell D. Jones ◽  
Marius D. Surleac ◽  
Andrei J. Petrescu ◽  
Darla Destephanis ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
High Grade ◽  
Serous Ovarian Cancer ◽  
Clonal Lineage

Neurofibromatosis type 1 and high-grade tumors of the central nervous system

2009 ◽  
Vol 26 (5) ◽  
pp. 663-667 ◽  
Author(s):  
Amy Rosenfeld ◽  
Robert Listernick ◽  
Joel Charrow ◽  
Stewart Goldman
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
High Grade ◽  
The Central Nervous System

High-grade spondyloretrolisthesis in a 12-year-old girl with neurofibromatosis type 1

2013 ◽  
Vol 22 (2) ◽  
pp. 110-116 ◽  
Author(s):  
Ana María Martín-Fuentes ◽  
Juan Pretell-Mazzini ◽  
Angel Curto de la Mano ◽  
Rafael Viña-Fernández
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
High Grade

Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals

2008 ◽  
Vol 47 (3) ◽  
pp. 238-246 ◽  
Author(s):  
Kiran K. Mantripragada ◽  
Matthew Caley ◽  
Phil Stephens ◽  
Christopher J. Jones ◽  
Lan Kluwe ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Telomerase Activity ◽  
High Grade ◽  
Nerve Sheath Tumors ◽  
Peripheral Nerve Sheath Tumors ◽  
Nerve Sheath

Aggressive Leptomeningeal Gliomatosis in Neurofibromatosis Type 1

2012 ◽  
Vol 30 (27) ◽  
pp. e269-e270 ◽  
Author(s):  
David Arkadir ◽  
Yakov Fellig ◽  
Moshe John Gomori ◽  
Eduard Linetsky ◽  
Edna Shalom ◽  
...  
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Leptomeningeal Gliomatosis

scholarly journals Multiple Neurofibromas with Hypertrichosis in a Filipino Patient with Neurofibromatosis 1

2019 ◽  
Vol 53 (2) ◽  
Author(s):  
Leah Antoinette M. Caro-Chang ◽  
Maria Franchesca S. Quinio ◽  
Georgina C. Pastorfide
Keyword(s):  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
The Philippines ◽  
Neurofibromatosis 1 ◽  
First Report ◽  
Lisch Nodules ◽  
Cutaneous Neurofibromas

This is a case of an 11-year-old male who presented with multiple neurofibromas with hypertrichosis. Classic cutaneous neurofibromas, café-au-lait macules, axillary freckling, Lisch nodules, and scoliosis were also present fulfilling a diagnosis of Neurofibromatosis type 1. This is the first report of multiple neurofibromas with hypertrichosis in the Philippines. Hypertrichosis overlying a neurofibroma is rarely reported and the mechanism remains to be elucidated.

scholarly journals Malignant Triton Tumors in Sisters with Clinical Neurofibromatosis Type 1

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Basnet Alina ◽  
Jofre A. Sebastian ◽  
Capo Gerardo
Keyword(s):  
Peripheral Nerve ◽  
Chest Wall ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Nerve Sheath Tumor ◽  
High Grade ◽  
Peripheral Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumors ◽  
Nerve Sheath

Malignant triton tumors (MTTs) are rare and aggressive sarcomas categorized as a subgroup of malignant peripheral nerve sheath tumors (MPNSTs). MTTs arise from Schwann cells of peripheral nerves or existing neurofibromas and have elements of rhabdomyoblastic differentiation. We report the occurrence of MTTs in two sisters. The first patient is a 36-year-old female who presented with left sided chest wall swelling. She also had clinical features consistent with neurofibromatosis type 1 (NF-1). Debulking of the mass showed high-grade malignant peripheral nerve sheath tumor with skeletal muscle differentiation (MTT). The patient was treated with ifosfamide and adriamycin along with radiation. Four years after treatment, she still has no evidence of disease recurrence. Her sister subsequently presented to us at the age of 42 with left sided lateral chest wall pain. Imaging showed a multicompartmental retroperitoneal cystic mass with left psoas involvement. The tumor was resected and, similarly to her sister, it showed high-grade malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation (MTT). The patient was started on chemotherapy and radiation as described above.

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