scholarly journals Sickle Cell Disease: Reference Values and Interhemispheric Differences of Nonimaging Transcranial Doppler Blood Flow Parameters

2011 ◽  
Vol 32 (8) ◽  
pp. 1444-1450 ◽  
Author(s):  
M. Arkuszewski ◽  
J. Krejza ◽  
R. Chen ◽  
J.L. Kwiatkowski ◽  
R. Ichord ◽  
...  
Keyword(s):  
Blood Flow ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Reference Values ◽  
Transcranial Doppler ◽  
Cell Disease ◽  
Flow Parameters

scholarly journals Use of Transcranial Doppler in Intensive Care Unit

2017 ◽  
Vol 3 (3) ◽  
pp. 99-104 ◽  
Author(s):  
Sandor Viski ◽  
Laszlo Olah
Keyword(s):  
Intensive Care Unit ◽  
Blood Flow ◽  
Intensive Care ◽  
Intracranial Pressure ◽  
Sickle Cell Disease ◽  
Intensive Care Units ◽  
Transcranial Doppler ◽  
Cell Disease ◽  
Flow Parameters ◽  
Intracranial Arteries

AbstractUse of transcranial Doppler has undergone much development since its introduction in 1982, making the technique suitable for general use in intensive care units. The main application in intensive care units is to assess intracranial pressure, confirm the lack of cerebral circulation in brain death, detect vasospasm in subarachnoid haemorrhage, and monitor the blood flow parameters during thrombolysis and carotid endarterectomy, as well as measuring stenosis of the main intracranial arteries in sickle cell disease in children. This review summarises the use of transcranial Doppler in intensive care units.

scholarly journals Is there a role for selective vasodilation in the management of sickle cell disease?

Blood ◽  
1988 ◽  
Vol 71 (3) ◽  
pp. 597-602 ◽  
Author(s):  
GP Rodgers ◽  
MS Roy ◽  
CT Noguchi ◽  
AN Schechter
Keyword(s):  
Blood Flow ◽  
Steady State ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Microvascular Obstruction ◽  
Controlled Study ◽  
Control Group ◽  
Cell Disease ◽  
Retinal Arteriolar

Abstract To test the hypothesis that microvascular obstruction to blood flow at the level of the arteriole may be significant in individuals with sickle cell anemia, the ophthalmologic effects of orally administered nifedipine were monitored in 11 steady-state patients. Three patients with evidence of acute peripheral retinal arteriolar occlusion displayed a prompt reperfusion of the involved segment. Two other patients showed fading of retroequatorial red retinal lesions. Color vision performance was improved in six of the nine patients tested. The majority of patients also demonstrated a significant decrease in the amount of blanching of the conjunctiva which reflects improved blood flow to this frequently involved area. Such improvements were not observable in a control group of untreated stable sickle cell subjects. These findings support the hypothesis that inappropriate vasoconstriction or frank vasospasm may be a significant factor in the pathogenesis of the microvascular lesions of sickle cell disease and, further, that selective microvascular entrapment inhibition may offer an additional strategy to the management of this disorder. We believe a larger, placebo-controlled study with nifedipine and similar agents is warranted.

scholarly journals Transcranial Doppler and Magnetic Resonance in Tanzanian Children With Sickle Cell Disease

Stroke ◽  
2019 ◽  
Vol 50 (7) ◽  
pp. 1719-1726 ◽  
Author(s):  
Edward N. Kija ◽  
Dawn E. Saunders ◽  
Emmanuel Munubhi ◽  
Angela Darekar ◽  
Simon Barker ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Transcranial Doppler ◽  
Cell Disease
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