Immunofluorescence Studies of Shope Papilloma Virus in Cottontail Rabbit Kidney Tissue Cultures

1968 ◽  
Vol 128 (4) ◽  
pp. 1025-1029 ◽  
Author(s):  
T. Osato ◽  
Y. Ito
1973 ◽  
Vol 137 (4) ◽  
pp. 1091-1096 ◽  
Author(s):  
Stanfield Rogers ◽  
A. Lowenthal ◽  
H. G. Terheggen ◽  
J. P. Columbo

Inoculation of the Shope virus in tissue cultures of human fibroblasts from a patient with a deficiency of the enzyme arginase results in an induction of arginase activity, apparently virus coded.


1941 ◽  
Vol 73 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Thorolf Packalén

By excising after varying intervals the site of inoculation of the rabbit skin injected intracutaneously with the Shope papilloma virus and titrating its virus content, it has been shown that demonstrable active virus disappears from the skin within approximately 24 hours. The disappearance of most of the virus within such a short time as 15 to 60 minutes makes a transportation of virus from the site of inoculation as a responsible factor unlikely. The rate of disappearance seems to be the same both in the domestic and in the cottontail rabbit.


Cryobiology ◽  
1968 ◽  
Vol 4 (4) ◽  
pp. 197-199 ◽  
Author(s):  
André Chagnon ◽  
Bertrand Couture ◽  
Vytautas Pavilanis

Virology ◽  
1960 ◽  
Vol 12 (1) ◽  
pp. 48-58 ◽  
Author(s):  
R.C Williams ◽  
S.J Kass ◽  
C.A Knight

1956 ◽  
Vol 34 (3) ◽  
pp. 600-618 ◽  
Author(s):  
E. Kovacs

Pools of normal tissue cultures were examined for enzymes associated with nucleic acid metabolism. Ribonucleases and desoxyribonucleases, 5-nucleotidases, simple nucleotidases, acid and alkaline phosphatases were studied, and certain others occasionally demonstrated. Characteristic behavior of these enzyme systems during the cultivation procedures, during growth, and during degeneration was described. Quantitative data indicate the presence of significant amounts of enzymes in the supernatant fluid. This accounts for the considerable loss in these specialized constituents during fluid changes. The bearing of these findings on the physiology and pathology of cultivated cells was discussed, as a working hypothesis, with special emphasis on poliomyelitis infection. The use of enzyme assays, as functional tests supplementing morphological methods in tissue cultivation, was recommended.


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