Synthesis and Characterization of Some New Heterocyclic Compounds and Their Antibacterial Study

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Zena G. Alrecabi ◽  
Zainab Amer ◽  
Naeemah Al-Lami

This study including prepared new colored esters containing heterocyclic with high molecular weights. In the first part of work we synthesized azo dyes [1,2] from the reaction p-toluidine with β-naphthol and o-nitro phenol, thin we synthesized Schiff bases [3,4] by the reaction anthranilic acid with benzaldehyde and dimethyl benzaldehyde. The reaction azo dyes (contain OH group) with Schiff base (contain COOH group) these led to produce the new colored esters [A1-A4]. The second part of work was modification the (C=N-) group in esters to heterocyclic compounds by reacting with phenyl iso cyanide to produce new β-lactam [B1-B4] and with anthranilic acid to get new hydroquinazoline [C1-C4]. All these compounds were characterized by physical properties and spectral methods FTIR, 1H-NMR and 13C-NMR.


2021 ◽  
Vol 37 (5) ◽  
pp. 1158-1166
Author(s):  
S.Syed Shafi ◽  
R. Rajesh ◽  
R. Subaash ◽  
S.Senthil kumar

Recently, heterocyclic compounds play important role in drug industries. The benzothiazole (BTA) is a bicyclic compound in heterocyclic because of their biological properties. In this paper the synthesis and characterization of benzothiazole were reported. The chemical structures of synthesized compounds were established based on spectral data of 1HNMR, 13CNMR, and IR. The mass of the novel compounds was established with the help of the LCMS test. The formation of the crystal was confirmed by powder XRD and the sharp peaks show the purity and crystalline nature of the samples. The photoluminescence spectra explain the optical property of the compound. The biological studies of synthesized compounds show that compound 5c possesses good antibacterial activity and compound 5d has good antifungal activity.


2019 ◽  
Vol 4 (4) ◽  
pp. 236-239
Author(s):  
Krushnakumar J. Jilariya ◽  
P.K. Patel ◽  
Yogesh J. Sanghani ◽  
Vijay D. Chodvadiya ◽  
Jayesh Babariya

A highly functionalized heterocyclic compounds series were synthesized, characterized and tested for biological evaluation against bacteria and fungus. This novel synthetic route involves Schiff base formation reaction of 1,3-diphenyl-1H-pyrazole-4-carbaldehyde with 4-(4-aminophenyl)morpholin-3-one in the presence of base and methanol as a solvent in good yield and high purity. All the synthesized compounds were characterized using IR, 1H NMR and mass spectroscopic techniques. All the compound screened for antimicrobial activity against standard drugs.


ChemInform ◽  
2013 ◽  
Vol 45 (1) ◽  
pp. no-no
Author(s):  
K. M. Shailaja ◽  
Dipukakoty Dipukakoty ◽  
B. Shivakumar ◽  
E. Jayachandran

Sign in / Sign up

Export Citation Format

Share Document