Synthetic approaches towards 5H-[1]benzopyrano[3,4-c]pyridin-5-ones
2005 ◽
Vol 2005
(1)
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pp. 38-40
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The construction of 5H-[1]benzopyrano[3,4-c]pyridin-5-ones 2 was achieved through the reaction of 1-aryl-3-(2-hydroxyphenyl)-2-propen-1-ones 1 with malononitrile in alcoholic KOH solution affording the compound 2 along with 2-alkoxy-4-amino-6-aryl-3,5-pyridinedicarbonitriles 3. Single crystal X-ray diffraction of 3e confirmed the established structure and excluded the formation of the isomeric product 4.