scholarly journals Analysis of the budgetary impact of alogliptin in type 2 diabetes and unachieved target glycemia with metformin

2021 ◽  
Vol 5 (9) ◽  
pp. 559-567
Author(s):  
S.V. Nedogoda ◽  
◽  
A.S. Salasyuk ◽  
I.N. Barykina ◽  
V.O. Lutova ◽  
...  

within the preferential medication supply according to the List of Vital and Essential Drugs. Patients and Methods: the analytical model of decision-making was created using the MS Excel software to analyze the budgetary impact and "missed opportunities" when using alogliptin compared to other DPP-4 inhibitors for T2D. This model included only direct medical costs for one patient (medical costs of medical treatment with DPP-4 inhibitors). The target population included adults with T2D who received DPP-4 inhibitors from the List of Vital and Essential Drugs to enhance ineffective therapy with metformin based on the monitoring of the IQVIA drug purchase in 2021. Results: complete switch to alogliptin in the target population (249,700 patients with T2D) eased the strain on a budget of the health care system by 18%, or 839.7 million of RUB, over a 1-year therapy. Considering the previously calculated penetration rate, the average budget savings of the health care system over a 5-year therapy will be 11% or 448.6 of RUB. In addition, the analysis of "missed opportunities" has demonstrated that prescribing alogliptin in adults with T2D (considering replacement schedule) allows for additional treatment of 13,693 patients within the first year and 146,311 patients within five years in a fixed budget. Conclusion: in T2D, alogliptin is more effective compared to other DPP-4 inhibitors in terms of economics due to lower cost and similar efficacy. KEYWORDS: diabetes, dipeptidyl peptidase 4 inhibitors, alogliptin, analysis of budgetary impact, pharmacoeconomics. FOR CITATION: Nedogoda S.V., Salasyuk A.S., Barykina I.N. et al. Analysis of the budgetary impact of alogliptin in type 2 diabetes and unachieved target glycemia with metformin. Russian Medical Inquiry. 2021;5(9):559–567 (in Russ.). DOI: 10.32364/2587-6821-2021-5-9-559-567.

2019 ◽  
Vol 53 (7) ◽  
pp. 675-682 ◽  
Author(s):  
David J. Taber ◽  
Ralph Ward ◽  
R. Neal Axon ◽  
Rebekah J. Walker ◽  
Leonard E. Egede ◽  
...  

2019 ◽  
Vol 45 (4) ◽  
pp. 431-441
Author(s):  
Lydia O’Meara ◽  
Susan L. Williams ◽  
Kate Ames ◽  
Celeste Lawson ◽  
Sonia Saluja ◽  
...  

PurposeThe purpose of this study was to examine associations among risk of type 2 diabetes (T2D), health literacy levels, and sociodemographic characteristics in a nonclinical adult population to assist in the development of effective T2D prevention programs.MethodsThe Health Literacy Questionnaire and Australian Type 2 Diabetes Risk Assessment Tool were included in an online survey. Participants were a random sample of adults residing in each Australian state and territory. Data were analyzed with descriptive statistics and multinomial logistic regression.ResultsA total of 1279 Australian adults participated (52% female; mean ± SD age, 61 ± 12 years). Most were at medium (42.4%) or high (46.9%) risk of developing T2D. The lowest health literacy scores were found for the domains “critical appraisal of health information” and “navigating the health care system.” After controlling for covariates, participants at the highest risk of developing T2D were significantly more likely to be unemployed, have ≥1 chronic conditions, or have a mental health condition. Furthermore, they were significantly more likely to develop T2D if they scored low in 1 of the following health literacy domains: critical appraisal of health information, navigating the health care system, actively managing health, social support, and health care provider support.ConclusionsHealth literacy was associated with increased risk for developing T2D and should therefore be part of diabetes prevention initiatives. Specifically, new health promotion initiatives need to help people develop skills required to critically appraise health information and navigate the health care system. Health practitioners and educators should ensure that health information developed for consumers is uncomplicated and easily understood.


2016 ◽  
Vol 19 (7) ◽  
pp. A351
Author(s):  
E Labrador Barba ◽  
A Hernandez Mijares ◽  
FJ Alonso Moreno ◽  
M Rodriguez de Miguel ◽  
ML Orera Peña ◽  
...  

2017 ◽  
Vol Volume 11 ◽  
pp. 707-718 ◽  
Author(s):  
Elena Labrador Barba ◽  
Marta Rodriguez de Miguel ◽  
Antonio Hernández Mijares ◽  
Francisco Javier Alonso-Moreno ◽  
Maria Luisa Orera Peña ◽  
...  

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