scholarly journals Renal tumors in children and adolescents (primary diagnostics based on a pilot study)

2021 ◽  
Vol 4 (2) ◽  
pp. 162-167
Author(s):  
E.A. Karavaeva ◽  
◽  
T.E. Taranushenko ◽  
A.V. Morgun ◽  
M.V. Borisova ◽  
...  
Keyword(s):  
Pilot Study ◽  
Children And Adolescents ◽  
Hematological Malignancies ◽  
Wilms Tumor ◽  
Hospital Setting ◽  
Renal Tumors ◽  
Renal Ultrasound ◽  
Krasnoyarsk Krai ◽  
Primary Diagnostics ◽  
Single Center Study

Aim: to assess the rate of detection and epidemiology of renal tumors in children of the Krasnoyarsk Krai and to specify some tumor characteristics during primary diagnostics. Patients and Methods: retrospective exploratory (pilot) dynamic single-center study was conducted. A group of 46 children and adolescents with renal tumors who were admitted to the Department of Hematological Malignancies for examinations and treatment in 2011–2019. All data were obtained from hospital register. Results: renal tumors account for 6.4% of hematological malignancies first diagnosed in children. 9-year primary incidence of renal tumors in children was, on average, 0.87 per 100,000 children, alternating between the increase and decrease in the detection rate. Renal tumors rank 4th among hematological malignancies in the Krasnoyarsk Krai children. The mean age was 4.1±0.5 years. No gender differences were revealed. In a pre-hospital setting, renal tumors were suspected in 24 children (52%). The most common complaints were abdominal pains (34 patients, 74%) and enlarged abdomen (30 patients, 65%). Most renal tumors (40 out of 46) were nephroblastoma as demonstrated by histology. The distribution by prognostic risk (the likelihood of recurrence and/or other unfavorable outcome) has shown that most patients have intermed iate (n=25, 54%) or high (n=19, 42%) risk. Conclusions: our findings illustrate that children with renal tumors require more attention of pediatricians in a pre-hospital setting (cancer vigilance about abdominal pains and enlarged abdomen in children) to reduce the time to diagnosis and to increase the use of renal ultrasound during checkups or in suspicious renal tumors. KEYWORDS: nephroblastoma, Wilms tumor, renal tumors, children, epidemiology, prevalence, primary diagnostics. FOR CITATION: Karavaeva E.A., Taranushenko T.E., Morgun A.V. et al. Renal tumors in children and adolescents (primary diagnostics based on a pilot study) . Russian Journal of Woman and Child Health. 2021;4(2):162–167. DOI: 10.32364/2618-8430-2021-4-2-162-167.

919: Ureteral Extension in Childhood Renal Tumors: A Report From the National Wilms Tumor Study Group (NWTSG)

2007 ◽  
Vol 177 (4S) ◽  
pp. 305-305
Author(s):  
Shane Daley ◽  
Michael Ritchey ◽  
Robert Shamberger ◽  
Robert Sawin ◽  
Thomas Hamilton ◽  
...  
Keyword(s):  
Wilms Tumor ◽  
Renal Tumors ◽  
Study Group ◽  
Tumor Study ◽  
Tumor Study Group

Seroprevalence of Bartonella species, Coxiella burnetii and Toxoplasma gondii among patients with hematological malignancies: A pilot study in Romania

2017 ◽  
Vol 64 (6) ◽  
pp. 485-490 ◽  
Author(s):  
C. J. Messinger ◽  
E. S. Gurzau ◽  
E. B. Breitschwerdt ◽  
C. I. Tomuleasa ◽  
S. J. Trufan ◽  
...  
Keyword(s):  
Pilot Study ◽  
Toxoplasma Gondii ◽  
Coxiella Burnetii ◽  
Hematological Malignancies ◽  
Bartonella Species

Accuracy of MRI in the Differential Diagnosis of Wilms Tumor

2021 ◽  
Vol 15 (8) ◽  
pp. 2057-2059
Author(s):  
Maham Ashraf ◽  
Aysha Anjum ◽  
Eisha Tahir ◽  
Amber Goraya ◽  
Rabia Aqeel
Keyword(s):  
Differential Diagnosis ◽  
Diagnostic Accuracy ◽  
Gold Standard ◽  
Wilms Tumor ◽  
Correct Diagnosis ◽  
Renal Tumors ◽  
Common Finding ◽  
Predictive Values ◽  
Female Ratio ◽  
Male Predominance

Background & Objective: Renal tumors are a common finding in diagnostic imaging; these lesions usually are solid or cystic, benign or malignant, and the correct diagnosis may be difficult. The current study aims at to determine the diagnostic accuracy of magnetic resonance imaging for the diagnosis of Wilms tumor taking histopathology as gold standard. Methodology: This cross-sectional study was carried at the Department of Radiology, The Children’s Hospital & Institute of Child Health Lahore over 6 months from March 2019 to September 2019. The study involved 125 children of both genders aged between 2 years to 14 years presenting with a neoplastic mass in the retroperitoneum on ultrasound abdomen during initial workup. These children were assessed on MRI for the diagnosis of Wilms tumor. Later the diagnosis was confirmed on histopathology which was taken as gold standard and the diagnosis of MRI was judged accordingly as true/false and positive/negative. A written informed consent was obtained from every patient. Results: The mean age of the children was 5.8±3.9 years having a male predominance with male to female ratio of 1.8:1. Wilms tumor was suspected in 13 (10.4%) children on MRI. The diagnosis of Wilms tumor was confirmed in 13 (10.4%) children on histopathology. MRI was found to be 76.9% sensitive, 97.3% specific and 95.2% accurate with positive and negative predictive values of 76.9% and 97.3% respectively. Conclusion: In the present study, MRI was found to be 95.2% accurate in the differential diagnosis of Wilms tumor in children presenting with retroperitoneal mass which along with its non-invasive and radiation free nature advocates the preferred use of MRI in the diagnostic evaluation of such children in future oncologic practice. Keywords: Retroperitoneal Tumor, Wilms Tumor, MRI, Diagnostic Accuracy

Pediatric Anastomosing Hemangioma: Case Report and Review of Renal Vascular Tumors in Children

2018 ◽  
Vol 22 (3) ◽  
pp. 269-275 ◽  
Author(s):  
Alvin B Caballes ◽  
Agustina D Abelardo ◽  
Miguel J Farolan ◽  
Januario Antonio D Veloso
Keyword(s):  
Case Report ◽  
Pediatric Patients ◽  
Wilms Tumor ◽  
Vascular Lesion ◽  
Renal Tumors ◽  
Vascular Tumors ◽  
Malignant Neoplasms ◽  
Therapeutic Implications ◽  
Renal Vascular ◽  
Anastomosing Hemangioma

The case involves a 10-year-old child who underwent a left radical nephrectomy for what was believed to be a Wilms’ tumor. Histopath examination indicated a benign vascular lesion, subsequently determined to be an anastomosing hemangioma of the kidney. A comparison with the previously cited pediatric patients with renal vascular tumors is provided, and the inconsistent diagnostic terminologies for these conditions are highlighted. The therapeutic implications of these predominantly benign renal tumors, in the context of the much more frequently encountered malignant neoplasms in children, are additionally discussed.

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