Intramuscular Route of Administration

2020 ◽  
Author(s):  
Keyword(s):  
Route Of Administration ◽  
Intramuscular Route

Des-enkephalin-γ-endorphin: bioavailability in rats following the subcutaneous and intramuscular route of administration

1986 ◽  
Vol 14 (2) ◽  
pp. 113-124 ◽  
Author(s):  
J. Coos Verhoef ◽  
Henk M. van den Wildenberg
Keyword(s):  
Route Of Administration ◽  
Intramuscular Route

scholarly journals Intramuscular Route of Administration Increases Potency in Eliciting Cocaine-Induced Behavioral Sensitization

2017 ◽  
Vol 6 (1) ◽  
pp. 36-42
Author(s):  
Beth A. Rice ◽  
Raza Tariq ◽  
Chana K. Akins
Keyword(s):  
Behavioral Sensitization ◽  
Route Of Administration ◽  
Intramuscular Route

Determination of Candida albicans fungus proteins concentration by Elisa method at Intramuscular Introduction in Candidiasis Therapy

2021 ◽  
pp. 3249-3252
Author(s):  
Mykola Rybalkin ◽  
Tatiana Diadiun ◽  
Natalia Khokhlenkova ◽  
Yuliia Azarenko ◽  
Serhiy Stepanenko
Keyword(s):  
Candida Albicans ◽  
Therapeutic Effect ◽  
Protein Concentration ◽  
Route Of Administration ◽  
Elisa Method ◽  
Defence Mechanisms ◽  
Intramuscular Route ◽  
Animal Body ◽  
Antibody Titers

The objective of this work was to determine the C. albicans fungus protein concentration at intramuscular introduction in therapy of candidiasis. Therapeutic effect of C. albicans fungus proteins in concentrations 1, 2, 3, 4 and 5mg/mL has been examined in white mice. Animals were infected intraperitoneally with suspension of C. albicans fungus strain CCM 335-867 in the amount of 20 million cells per 1mL volume. After 5 days and repeatedly after 14 days mice were injected intramuscularly in the upper back hind paw with proteins of Candida fungus cells of volume 0.2mL. 14 days after each injection, the determination of the protective functions of the animal body has been carried out by the titer of specific C. albicans antibodies during immunoassay. According to the data obtained during studies on the treatment of candidiasis, it has been found that in the intramuscular route of administration after the first injection with C. albicans protein concentration of 3 mg/mL antibody titers increased 2 times, and after the second - 8 times. Proteins of C. albicans fungus at a concentration of 3 mg/mL activate the body's defence mechanisms.

The Clinical Pharmacology of Methylprednisolone Sodium Phosphate. I. Intramuscular Route of Administration

1977 ◽  
Vol 17 (5-6) ◽  
pp. 324-333 ◽  
Author(s):  
E. NOVAK ◽  
A. R. DiSANTO ◽  
C. E. SECKMAN ◽  
G. ELLIOTT ◽  
J. G. LEE ◽  
...  
Keyword(s):  
Clinical Pharmacology ◽  
Sodium Phosphate ◽  
Route Of Administration ◽  
Intramuscular Route

1113: Route of Administration Influences the Antitumor Effect of Bone Marrow Derived Dendritic Cells Engineered to Produce Interleukin-12 in A Metastatic Mouse Prostate Cancer Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 293-294
Author(s):  
Takashi Saika ◽  
Takefumi Satoh ◽  
Nobuyuki Kusaka ◽  
Shin Ebara ◽  
Vladimir B. Mouraviev ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Bone Marrow ◽  
Dendritic Cells ◽  
Antitumor Effect ◽  
Route Of Administration ◽  
Interleukin 12 ◽  
Cancer Model ◽  
Mouse Prostate ◽  
Prostate Cancer Model

Intrabursal Route of Administration

2020 ◽  
Author(s):  
Keyword(s):  
Route Of Administration

Sublingual Route of Administration

2020 ◽  
Author(s):  
Keyword(s):  
Route Of Administration

Intramedullary Route of Administration

2020 ◽  
Author(s):  
Keyword(s):  
Route Of Administration

An Overview of Second Generation Nanoparticles− Nanostructure Lipid Carrier Drug Delivery System

2020 ◽  
Vol 13 (6) ◽  
pp. 5181-5189
Author(s):  
Prabhat Kumar Sahoo ◽  
Neha S.L ◽  
Arzoo Pannu
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Second Generation ◽  
Drug Loading ◽  
Scale Up ◽  
Delivery Systems ◽  
Route Of Administration ◽  
Random Structure ◽  
Stability Parameters

Lipids are used as vehicles for the preparation of various formulations prescribed for administrations, including emulsions, ointments, suspension, tablets, and suppositories. The first parental nano-emulsion was discovered from the 1950s when it was added to the intravenous administration of lipid and lipid-soluble substances. Lipid-based drug delivery systems are important nowadays. Solid nanoparticles (SLN) and Nanostructured lipid carriers (NLC) are very proficient due to the ease of production process, scale-up capability, bio-compatibility, the biodegradability of formulation components and other specific features of the proposed route. The administration or nature of the materials must be loaded into these delivery systems. The main objectives of this review are to discuss an overview of second-generation nanoparticles, their limitations, structures, and route of administration, with emphasis on the effectiveness of such formulations. NLC is the second generation of lipid nanoparticles having a structure like nanoemulsion. The first generation of nanoparticles was SLN. The difference between both of them is at its core. Both of them are a colloidal carrier in submicron size in the range of 40-1000 nm. NLC is the most promising novel drug delivery system over the SLN due to solving the problem of drug loading and drug crystallinity. Solid and liquid lipids combination in NLC formation, improve its quality as compare to SLN. NLC has three types of structures: random, amorphous, and multiple. The random structure containing solid-liquid lipids and consisting crystal and the liquid lipid irregular in shape; thereby enhance the ability of the lipid layer to pass through the membrane. The second is the amorphous structure. It is less crystalline in nature and can prevent the leakage of the loaded drug. The third type is multiple structures, which have higher liquid lipid concentrations than other types. The excipients used to form the NLC are bio-compatible, biodegradable and non-irritating, most of which can be detected using GRAS. NLC is a promising delivery system to deliver the drug through pulmonary, ocular, CNS, and oral route of administration. Various methods of preparation and composition of NLC influence its stability Parameters. In recent years at the educational level, the potential of NLC as a delivery mechanism targeting various organs has been investigated in detail.

Safety and efficacy of an attenuated heartwater (Ehrlichia ruminantium) vaccine administered by the intramuscular route in cattle, sheep and Angora goats

Vaccine ◽  
2020 ◽  
Vol 38 (49) ◽  
pp. 7780-7788
Author(s):  
Abdalla A. Latif ◽  
Helena C. Steyn ◽  
Antoinette I. Josemans ◽  
Ratselane D. Marumo ◽  
Alri Pretorius ◽  
...  
Keyword(s):  
Safety And Efficacy ◽  
Ehrlichia Ruminantium ◽  
Intramuscular Route ◽  
Angora Goats
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