scholarly journals Pillar Cell

2020 ◽  
Author(s):  
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1999 ◽  
Vol 202 (9) ◽  
pp. 1151-1157 ◽  
Author(s):  
K.O. Stenslokken ◽  
L. Sundin ◽  
G.E. Nilsson

Endothelin-1 (ET-1) has been shown to cause a considerable increase in the vascular resistance of fish gills. In trout, recent evidence suggest that this is the result of pillar cell contraction in the gill lamellae. Using epi-illumination microscopy to observe the gill lamellae of anaesthetised Atlantic cod (Gadus morhua), we show that ET-1 (100 ng kg-1, injected into the ventral aorta) causes an increase in pillar cell diameter, consistent with pillar cell contraction, and a shift of intralamellar blood flow from the lamellar sheet to the outer marginal channels. Simultaneously, there was an increase in ventral aortic blood pressure, a reduction in cardiac output, an increase in gill vascular resistance and a reduction in the oxygen partial pressure of venous blood. All these effects were blocked by the ETA/ETB receptor antagonist bosentan (5 mg kg-1). Pillar cell contraction is likely to be a mechanism for matching the functional respiratory surface area with the instantaneous respiratory needs of the fish.



Toxics ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 97
Author(s):  
Rachele Macirella ◽  
Vittoria Curcio ◽  
Elvira Brunelli

Chlorpyrifos (CPF) is an organophosphorus insecticide commonly used for domestic and agricultural purposes. The risk posed by environmental contamination from CPF is well acknowledged, and it has been detected worldwide in aquatic habitats and coastal areas. In addition, due to its slower degradation in seawater compared to freshwater, CPF is of particular concern for marine environments. Here, we investigated for the first time the morpho-functional alterations induced by CPF on the gills of Thalassoma pavo, a widespread species in the Mediterranean Sea. We tested the effects of two sublethal concentrations (4 and 8 µg/L) after 48 and 96 h. Our study demonstrates that the alterations induced by CPF are dose and time-dependent and highlight the harmful properties of this insecticide. After exposure to the low tested concentration, the more frequent alteration is an intense proliferation of the primary epithelium, whereas after exposure to the high concentration, the primary epithelium proliferation is less extensive, and the most evident effects are the thinning of secondary lamellae and the ectopia of chloride and goblet cells. CPF also modulated the expression of Na+/K+-ATPase. Dilation of lamellar apical tips, pillar cell degeneration, and appearance of aneurysms are often observed.



2018 ◽  
Vol 65 (11) ◽  
pp. 5172-5179 ◽  
Author(s):  
Wei-Chih Chien ◽  
Chiao-Wen Yeh ◽  
Robert L. Bruce ◽  
Huai-Yu Cheng ◽  
I. T. Kuo ◽  
...  
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Author(s):  
N. Gong ◽  
W.C. Chien ◽  
A. Ray ◽  
L.M. Gignac ◽  
C.W. Yeh ◽  
...  
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1999 ◽  
Vol 37 ◽  
pp. 13-21 ◽  
Author(s):  
NS Lee ◽  
Y Nomura ◽  
T Miyazaki
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1983 ◽  
Vol 31 (5) ◽  
pp. 651 ◽  
Author(s):  
BJ Gannon ◽  
DJ Randall ◽  
J Browing ◽  
RJG Lester ◽  
LJ Rogers

The general organization of the gill microvasculature of Neoceratodus is similar to that reported for elasmobranchs. A corpus cavernosum is situated between the afferent filamental artery and afferent lamellar arterioles. The microvascular network of the lamellar blood sheet consists of a series of major channels, curving in concentric arcs from afferent to efferent lamellar arterioles, with minor radial cross-connections between these major channels; the basal lamellar channels are not buried in the filament. The afferent filamental arteries also supply blood to the interbranchial septum, which extends almost to the filament tip. The water-blood barrier of 3-4 �m consists of up to three cells: the surface epithelial cell, the pillar cell flange. plus a frequently interposed interstitial cell; there is a prominent basal lamina immediately external to the pillar cell flange. Adjacent gill secondary lamellae are commonly fused at their free margins near the leading edge into groups of from two to five. The micro-organization of the pseudobranch is in general similar to that of the posterior holobranchs. The lung is divided into a series of air sacs by stout septae which contain large amounts of smooth muscle. The respiratory epithelium is of two types: a squamous epithelium underlain by a dense capillary sheet, and isolated patches of a columnar muco-ciliary epithelium associated with only few capillaries. The air-blood barrier (approximately 3 �m thick) consists of a squamous epithelial cell process and attenuated vesiculated endothelial cell cytoplasm, with two basal laminae and intervening interstitial space situated between these.



Author(s):  
C. W. Yeh ◽  
W. C. Chien ◽  
R. L. Bruce ◽  
H. Y. Cheng ◽  
I. T. Kuo ◽  
...  
Keyword(s):  


Development ◽  
2007 ◽  
Vol 134 (16) ◽  
pp. 3021-3029 ◽  
Author(s):  
B. E. Jacques ◽  
M. E. Montcouquiol ◽  
E. M. Layman ◽  
M. Lewandoski ◽  
M. W. Kelley


1977 ◽  
Vol 233 (3) ◽  
pp. R145-R161
Author(s):  
D. G. Smith ◽  
D. W. Johnson

The complex blood flow patterns occurring in a trout secondary lamella were computed from a theoretical electrical model consisting of a two-dimensional array of unitary resistances representing the blood channels of the lamella. Estimates of oxygen uptake from water to blood were made by means of the standard conductance equations for oxygen and values from the literature for blood and water PO2's in trout. The results were plotted as contour charts of blood and water PO2, O2 transfer, and blood flow. According to the results of various manipulations of this model, oxygen exchange across a given lamella will be largely unaffected by changes in the overall shape of the lamella. However, the model predicted that oxygen exchange would be greatly reduced if 1) the basal pillar cell channels were denied access to the respiratory water flow, 2) pillar cell contraction were to force blood into the larger-diameter marginal channels, or 3) the blood flow rate were to be increased, regardless of a concomitant increase in water flow. These predictions are discussed in terms of current theories of gas exchange in teleost gills.



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