scholarly journals AN EPIDEMIOLOGICAL STUDY OF VARICOCELE

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Dinesh Singh Yadav ◽  
Dr. Farukh Khan
Keyword(s):  
Prospective Study ◽  
Epidemiological Study ◽  
General Surgery ◽  
Large Scale ◽  
Inclusion Criteria ◽  
Clinical Factors ◽  
Study Duration ◽  
Pampiniform Plexus

Background A varicocele is described as pathologically enlarged, tortuous veins of the pampiniform plexus, leading to an increased testicular temperature and adrenal metabolite reflux into the testes. The purpose of this work was to find presentations of “varicocele. Methods Hospital based prospective study conducted on 50 cases reporting to General surgery, Paed. Surgery and urology department within the study duration and eligible as per inclusion criteria was included in study. Results- Most of the patients (56.00%) were presented with pain and dragging sensations followed by 28.00%  patients were presented for infertility and  16.00% patients were did not have any complaints but referred from various recruitment agencies for fitness purposes.Out 50 patients 48% patients were treated by palmos technique and 36.00% patients were treated by high inguinal ligation Conclusion It conclude that Varicocele epidemiology remains incompletely understood. We need well‑designed, large‑scale studies that include evaluation of important clinical factors to comprehend fully the epidemiological aspects of this condition. Keywords- Varicocele, epidemiology, urology

scholarly journals AN EPIDEMIOLOGICAL STUDY OF VARICOCELE

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Anil Kumar Dadhich ◽  
Ramgopal Meena
Keyword(s):  
General Population ◽  
Prospective Study ◽  
Epidemiological Study ◽  
General Surgery ◽  
Large Scale ◽  
Inclusion Criteria ◽  
Clinical Factors ◽  
Primary Infertility ◽  
Pampiniform Plexus ◽  
Surgery Department

Background: Varicocele, an abnormal dilatation and tortuosity of the pampiniform plexus of veins is found in about 15% of the general population with a marked left sided predominance. However this incidence rises to 35% in men with primary infertility and 70 to 80% in men with secondary infertility. Methods: Hospital based prospective study conducted on 100 cases reporting to General surgery department within the study duration and eligible as per inclusion criteria was included in study. Results: In our study out of Out of 100 patients maximum 42.00% patients were farmer followed by 22.00% patients were Coolies and Rickshaw Pullers, 17.00% patients were students, 10.00% were laborer and 9.00% were policemen. Conclusion: It conclude that Varicocele epidemiology remains incompletely understood. We need well‑designed, large‑scale studies that include evaluation of important clinical factors to comprehend fully the epidemiological aspects of this condition.

scholarly journals AN EPIDEMIOLOGICAL STUDY OF VARICOCELE

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Dr. Sanvar Mal Kantva ◽  
Dr. Mahendra Kumar
Keyword(s):  
General Population ◽  
Prospective Study ◽  
Epidemiological Study ◽  
General Surgery ◽  
Large Scale ◽  
Inclusion Criteria ◽  
Clinical Factors ◽  
Primary Infertility ◽  
Pampiniform Plexus ◽  
Surgery Department

Background: Varicocele, an abnormal dilatation and tortuosity of the pampiniform plexus of veins is found in about 15% of the general population with a marked left sided predominance. However this incidence rises to 35% in men with primary infertility and 70 to 80% in men with secondary infertility. Methods: Hospital based prospective study conducted on 100 cases reporting to General surgery department within the study duration and eligible as per inclusion criteria was included in study. Results: In our study out of Out of 100 patients maximum 42.00% patients were farmer followed by 22.00% patients were Coolies and Rickshaw Pullers, 17.00% patients were students, 10.00% were laborer and 9.00% were policemen. Conclusion: It conclude that Varicocele epidemiology remains incompletely understood. We need well‑designed, large‑scale studies that include evaluation of important clinical factors to comprehend fully the epidemiological aspects of this condition.

Wireless parathyroid detection device using autofluorescence and smart glasses: A preliminary study

2021 ◽  
pp. 1-9
Author(s):  
Chang Hwan Ryu ◽  
Jungirl Seok ◽  
Yu Lim Choi ◽  
Seok-ki Kim ◽  
Yuh-Seog Jung ◽  
...  
Keyword(s):  
Prospective Study ◽  
Large Scale ◽  
Video Recording ◽  
Controlled Study ◽  
Autofluorescence Imaging ◽  
Agreement Rate ◽  
Smart Glasses ◽  
Practical Effect ◽  
Preliminary Study ◽  
Positive Agreement

BACKGROUND: Autofluorescence imaging technology has been utilized for preserving or identifying parathyroid glands (PTGs) during thyroid surgery. We developed a wireless PTGs detection device linked with smart glasses that allows for real-time video recording and screen switching according to the light source. OBJECTIVE: This study aimed to confirm the feasibility of the device and whether it would help preserve the PTG during the surgery. METHODS: This prospective study was conducted in 30 patients with 66 PTGs. The device’s agreement with the physician’s judgment was evaluated, and we determined how many PTGs were preserved from thyroidectomy. RESULTS: The positive agreement rate for PTGs detection between the surgeon and device was 70.9%. Inadvertent parathyroidectomy was identified in surgical specimens of 6 patients (20%). No PTG was removed when it was confirmed by the device (0/39). Of the 27 glands not detected by the device, there was inadvertent removal of 6 PTGs. CONCLUSIONS: PTGs can be preserved successfully when the detection of them by the device is consistent with the surgeon’s discretion. A large-scale controlled study is necessary to demonstrate the practical effect of this device on hypoparathyroidism after thyroidectomy.

scholarly journals Large Scale, Multicenter, Prospective Study of Apatinib in Advanced Gastric Cancer: A Real-World Study from China [Corrigendum]

2020 ◽  
Vol Volume 12 ◽  
pp. 8409-8410
Author(s):  
Wanren Peng ◽  
Fenglin Zhang ◽  
Zishu Wang ◽  
Dongliang Li ◽  
Yifu He ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prospective Study ◽  
Advanced Gastric Cancer ◽  
Real World ◽  
Large Scale ◽  
Multicenter Prospective Study

scholarly journals Evaluation of Fibrotic Changes in OSMF:A Retrospective Study Using Special Stains and Polarizing Microscopy

2017 ◽  
Vol 6 (2) ◽  
pp. 1518
Author(s):  
Parvez Ikram ◽  
Nadeem Jeddy
Keyword(s):  
Connective Tissue ◽  
Large Scale ◽  
Oral Submucous Fibrosis ◽  
Muscle Layer ◽  
Inclusion Criteria ◽  
Polarizing Microscopy ◽  
Potentially Malignant ◽  
Tissue Changes ◽  
Submucous Fibrosis ◽  
Picrosirius Red

<p><strong>Background:</strong> Oral submucous fibrosis (OSMF), a potentially malignant oral disorder has the highest rate of malignant transformation of about 7-13%. The connective tissue changes that occur in this disease are characteristic and are stained with special stains.</p><p><strong>Objective:</strong> The study was done to compare common and special stains under light microscopy and polarizing microscopy to evaluate the levels of fibrosis in oral submucous fibrosis and assess the type of collagen present in the stromal area.</p><p><strong>Materials and Methods:</strong> Fifty tissue blocks were selected from the archives and were prepared and stained with H&amp;E, Masson's trichrome, Van Gieson and Picrosirius red and studied under light microscope and polarizing microscope respectively.</p><p><strong>Results:</strong> H and E stained slides were useful in diagnosing the lesion but was not able to highlight the level of fibrosis. Masson's trichrome and Van Gieson stained slides showed the depth of the lesion which extended even to the deeper muscle layer. The type of collagen present was definitively seen by the birefringence in polarizing microscopic study. Interobserver variation was less and all the values regarding the effectiveness of the special stains in detecting the level of fibrosis were statistically significant.</p><p><strong>Conclusion:</strong> Special stains can be used routinely in laboratories to demonstrate connective tissue lesions especially in cases of OSMF. Depth of the lesion and the area of involvement help in treatment planning to be delivered. Large scale studies with more categories and inclusion criteria are required along with the special stains to assess the other alterations in OSMF.</p>

Community-wide screening of symptomatic and asymptomatic infection of Mycobacterium tuberculosis in the Saharia tribe of India

2021 ◽  
Vol 24 ◽  
Author(s):  
Pushpendra Singh ◽  
Ravindra Kumar ◽  
Aparup Das
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Epidemiological Study ◽  
Molecular Diagnosis ◽  
Random Sampling ◽  
Large Scale ◽  
Asymptomatic Infection ◽  
Causal Pathogen ◽  
Asymptomatic Individuals ◽  
Large Scale Screening ◽  
Screening Approaches

Background: Tuberculosis (TB) elimination program in India relies on detecting symptomatic patients through molecular diagnosis and providing speedy treatment, leaving individuals with no classical symptoms of TB (asymptomatic) behind in the population. Considering the contribution of such asymptomatic individuals to transmission of TB, it is important to timely identify them, especially in high-endemic settings. However, no community-level study has so far been conducted to record the incidences of asymptomatic cases in India. Therefore, this study was planned to know whether Mycobacterium tuberculosis, the causal pathogen of TB is prevalent in individuals presenting no classical symptoms in a highly endemic populations belonging to Saharia tribe, a Particularly Vulnerable Tribal Group (PVTG) in India. Methods: We performed molecular epidemiological study in 15 villages (n= 808) of Pohri block, Shivpuri district, Madhya Pradesh, India following population-wide random sampling of both symptomatic (ns=216) and asymptomatic (na=592) individuals. Though a total of 890 subjects were involved in the study, the sputum samples for the qPCR test could be collected only from 808 subjects. Detection of M. tuberculosis in sputum samples was done using TaqMan chemistry-based qPCR assay. Results: Sixteen (2.7%) individuals were found to be positive of M. tuberculosis among the 592 asymptomatic cases. The prevalence of M. tuberculosis DNA positivity was comparable between symptomatic (2.3%) and asymptomatic (2.7%) individuals. Conclusion: The present findings, though preliminary, pending large-scale screening approaches in other high-endemic populations employing both classical and advanced diagnosis methods, are daunting. Such community-wide screening approaches should therefore be integrated in the program if TB-free India is to be achieved by the year 2025.

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