scholarly journals ACCURACY OF CT-SCAN FOR THE DETECTION OF MALIGNANT LIVER MASS

Author(s):  
Nitu Panwar ◽  
Deepak Meena ◽  
G. L. Meena

Background: Malignant liver mass, especially hepatocellular carcinoma (HCC), is the most common primary malignant tumour of the liver representing more than 80% of all primary hepatic malignancies. Methods: This cross sectional study was carried out in the Department of Radiology. All the clinically suspected patients having hepatic mass at any age with both sexes who were attended in hospital were taken as study population as per inclusion and exclusion criteria. Patients having hepatomegaly due to extra hepatic causes, patients who refused to undergo CT-scan, patients who refuse to do biopsy or whose biopsy result was not available and patients having known hypersensitivity reaction to contrast agent were excluded from this study. Results: Sensitivity of CT to diagnose malignant lesion was 94.12%, specificity 84.62%, accuracy 90%, positive predictive value 88.89% and negative predictive value 91.67%. Conclusion: The results of the present study therefore conclude that CT is a useful modality for the diagnosis of malignant liver masses. Since the CT diagnosis correlates with histopathological connection, it is a sensitive modality on the basis of the above findings. Keywords: Test accuracy, CT-Scan, Malignant, Liver Mass

2020 ◽  
pp. 1-2
Author(s):  
Bhanupriya Singh ◽  
Khushal N Pawar ◽  
Suhas S Ghule ◽  
Dilip L Lakhkar

Background: More than 80% of all primary hepatic malignancies are hepatocellular carcinoma. Identification of a liver lesion depends on the attenuation difference between normal liver and the lesion. CT helps in detecting tumors and their size in liver quiet successfully. Accurate detection of liver mass is crucial for the deciding the treatment regimens. Objective: The study was undertaken to compare the results of CT-scan to histopathology findings. Methodology: This cross-sectional study was carried out in the Department of Radiodiagnosis and Imaging, Dr. Vitthalrao Vikhe Patil Foundation’s Medical College, Ahmednagar in association with Department of pathology of the concerned institute for histopathological diagnosis from 01-03-2014 to 28-02-2015 for a period of one year. Patients having hepatic mass of any sex or age presenting in the hospital were included in the study. The exclusion criteria were as patients refusing consent, or CT-scan and/or biopsy, known adverse reaction to contrast agent. CT scan and histopathology were done in all the subjects. Result: 50 subjects were studied in this study. Mean age of all subjects was 52.88 ± 16.03 years with a range of 18 year to 85 years. 40 cases were male in the study group. Maximum number of cases were in the age group 40-59 years. Out of 28 confirmed malignant cases by histopathology, 27 cases were diagnosed as malignant by CT scan too. Sensitivity of CT to diagnose malignant lesion was 96.4%, specificity 86.4%, accuracy 92%, positive predictive value 90% and negative predictive value 95%. Conclusion: CT scan can be used as a tool for the detecting of malignant liver masses.


2014 ◽  
Vol 31 (4) ◽  
pp. 189-193
Author(s):  
T Islam ◽  
SA Azad ◽  
ME Karim ◽  
L Khondker ◽  
K Rahman

A cross sectional study carried out with patients having suspected paranasal sinus (PNS) mass during January 2009 to October 2010 to evaluate the fungal diseases in PNS by computed tomographic(CT) image and comparison of the findings of this modality with histopathological result. Among the total 76 patients, the mean age of the patients was 35.95 ± 18.24 and common complaints of the patients were nasal obstruction (73.7%) and maximum 53.9% patients had PNS mass in maxillary sinuses. Out of all cases 10 were diagnosed as having fungal infection/mass by CT scan and confirmed by histopathological evaluation. Two cases were diagnosed as having fungal infection/mass by CT scan but not confirmed by histopathological findings. Of 64 cases of other than fungal infection/mass, which were diagnosed by CT scan, six were confirmed as having fungal infection/mass and 58 were other than having fungal infection/mass by histopathology. Sensitivity of CT scan to diagnose fungal infection/mass was 62.5%, specificity 96.7%, positive predictive value 83.3%, negative predictive value 90.6% and accuracy 89.5%. CT scan of the fungal diseases in paranasal sinus provides more information and better image quality and CT diagnosis correlate well with the findings of histopathology. DOI: http://dx.doi.org/10.3329/jbcps.v31i4.21002 J Bangladesh Coll Phys Surg 2013; 31: 189-193


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Hossein Abdolrahimzadeh Fard ◽  
Salahaddin Mahmudi-Azer ◽  
Sepideh Sefidbakht ◽  
Pooya Iranpour ◽  
Shahram Bolandparvaz ◽  
...  

Background. The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT  scan as a screening measure of COVID-19 in trauma patients. Methods. This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT scans were evaluated in a blinded manner, and the main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two Radiological Society of North America (RSNA) categories with the highest probability of COVID-19 pneumonia (i.e., typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID-19 pneumonia into “negative CT scan group.” Results. Chest CT scan had a sensitivity of 68%, specificity of 56%, positive predictive value of 34.8%, negative predictive value of 83.7%, and accuracy of 59.3% in detecting COVID-19 among trauma patients. Moreover, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals, a sensitivity of 100%, specificity of 66.7%, and negative predictive value of 100% were obtained ( p value: 0.05). Conclusion. Findings of the study indicated that the CT scan’s sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 compared with nontraumatic people.


2015 ◽  
Vol 04 (02) ◽  
pp. 27-31
Author(s):  
Wahida Begum ◽  
Biswajit Bhowmik ◽  
Khondker Shaheed Hussain ◽  
Md. Abdullah Yusuf

2020 ◽  
Vol 11 (4) ◽  
pp. 6282-6285
Author(s):  
Annamalai T T ◽  
Yuvaraj Muralidharan

Malignant liver mass remains a major health problem worldwide. Patients with chronic liver disease, the accuracy of ultrasound scan (US), spiral computed tomography (CT), magnetic resonance imaging (MRI), and alpha-fetoprotein (AFP) in diagnosing hepatocellular carcinoma (HCC) and malignant liver disease is assessed in this study. This study helps to find out the significance of serum alpha protein in patients with malignant liver mass. Retrospective cross-sectional study was done on patients with malignant liver mass. A total of 62 patients were diagnosed with malignant liver mass, out of which 44 are male, and 18 were female. They were grouped into three age groups 30-50 years, 51-70 years and above 70 years. In this study, out of the radiologically diagnosed malignant liver mass, HPE has proven hepatocellular carcinoma where 67.7% and liver secondaries where 29.03%. 55% of malignant liver mass has raised alpha feto proteins. 74% of HCC diagnosed and confirmed on biopsy have elevated alpha feto proteins. Only 11% of multiple malignant liver lesions have elevated alpha feto proteins.AFP receptors are expressed only in the AFP-positive HCC tissues. In the AFP-negative HCC, the rate of tumour growth would probably be expected to be relatively slow, and tumour staging might be lower than in AFP-positive. Based on this study, radiological imaging has been very useful in the diagnosis of various malignant liver masses in both elevated and normal AFP.


2014 ◽  
Vol 41 (2) ◽  
pp. 27-30 ◽  
Author(s):  
T Islam ◽  
M Rahman ◽  
S Nabi ◽  
L Khondker ◽  
S Sultana

Computed tomography (CT) is the gold standard for exact delineation of paranasal sinus(PNS) disease. There are many radiologically important diseases of paranasal sinuses. Objective of the study was to evaluate the role of computed tomographic image(CT) in the diagnosis of nasopharyngeal angiofibroma. A cross sectional study was carried out in the department of Radiology & Imaging, Bangabandhu Sheikh Mujib Medical University(BSMMU), Dhaka in collaboration with department of Otolaryngology and department of Pathology of BSMMU. This study was carried out with patients having suspected PNS mass and the duration of the study was from January 2009 to October 2010. Maximum 30.3% patients were belonged to 46 to 60 years age group and of them maximum 73.7% had complaints of nasal obstruction. Maximum 53.9% patients had PNS mass in maxillary sinuses and out of all cases 8 were diagnosed as having nasopharyngeal angiofibroma by CT scan and confirmed by histopathological evaluation. Two cases were diagnosed as having nasopharyngeal angiofibroma by CT scan but not confirmed by histopathological findings. By CT evaluation total 66 cases were diagnosed as having other than nasopharyngeal angiofibroma and confirmed by histopathology. Sensitivity of CT scan to diagnose nasopharyngeal angiofibroma was 100.0%, specificity 97.1 %, positive predictive value 80.0%, negative predictive value 100.0% and accuracy 97.4%. In conclusion, CT scan of the nasopharyngeal angiofibroma in para nasal sinus provides more information and better image quality and CT diagnosis correlate well with the findings of histopathology. DOI: http://dx.doi.org/10.3329/bmj.v41i2.18801 Bangladesh Medical Journal 2012 Vol. 41 No. 2: 27-30


2019 ◽  
Vol 24 (2) ◽  
pp. 149-155
Author(s):  
Lodh Dipankar ◽  
Islam Nazmul ◽  
Talukder Debesh ◽  
Majumder Rita ◽  
Arafat Shahriar ◽  
...  

Objective: To establish CT scan as a sensitive modality in the diagnosis of sinonasal mass by correlating with the findings of histopathological examination Methods: This cross sectional study was conducted in Dhaka Medical College Hospital (DMCH) from 01/07/2013 to 30/06/2014. A total of 32 cases were studied. Results: In this study male and female ratio was 1.4:1. So, the incidence of sinonasal mass slightly higher in male (59.3%) compared to the female (40.6%). Incidence of malignant tumour was found more in age group above 60 years. Out of 32 patients, 6 patients (18.7%) were diagnosed histopathologically as infective, 7 patients (21.8%) were benign and 19 patients (59%) had malignant sinonasal mass. Conclusion: Computed tomography (CT) scan examination of the sinonasal mass correlate well in most of the cases with histopathological results. It is therefore can be concluded that CT examination of nose and paranasal sinuses is a useful modality in the evaluation of sinonasal mass.  Bangladesh J of Otorhinolaryngology; October 2018; 24(2): 149-155


2020 ◽  
Author(s):  
Hossein Abdolrahimzadeh Fard ◽  
Salahaddin Mahmudi-Azer ◽  
Sepideh Sefidbakht ◽  
Pooya Iranpour ◽  
Shahram Bolandparvaz ◽  
...  

Abstract Purpose: The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT scan as a screening measure of COVID-19 in trauma patients.Methods: This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT-scans were evaluated in a blinded manner and main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two RSNA categories with the highest probability of COVID pneumonia (i.e. typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID pneumonia into “negative CT scan group”.Results: Chest CT scan had a sensitivity (68%), specificity (56%), positive predictive value (34.8%), negative predictive value (83.7%), and accuracy (59.3%) in detecting COVID-19 among trauma patients. Also, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals a sensitivity of 100% and a specificity of 66.7% and a negative predictive value of 100% was obtained.Conclusion: Findings of the study indicated that the CT scan's sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 in comparison to non-traumatic people.


2020 ◽  
Author(s):  
Ingerid Laukli ◽  
Heidi Kristin Ormstad ◽  
Leiv Sandvik

Abstract Background Detection of frailty may be essential to prevent or delay disability in home-dwelling elderly who seek formal assistance for the first time. The prevalence of frailty among elderly, first-time seekers of formal assistance in Norway, is unknown. Simple tests like Short Physical Performance Battery (SPPB) or assessment of gait speed (GS) may identify frailty. The aim of this study was to investigate the prevalence of frailty in this population, and to investigate the test accuracy of GS and SPPB to detect frailty.Methods We conducted a cross-sectional study of 116 home dwelling elderly > 65 years seeking formal assistance for the first time. Frailty was assessed by an adapted version of Fried Frailty Phenotype (FFP), GS was measured over 4 meters, and physical function was assessed by the Norwegian version of SPPB. The test accuracy for frailty (FFP) of GS < 0.8 m/s, SPPB < 10 and SPPB < 10 were assessed.Results 62.1%, 29.3% and 8.6% of the participants were frail, prefrail and non-frail, respectively. No association was found between age and degree of frailty. Both GS and SPPB-scores were significantly lower in the frail group than in the prefrail group, as well as significantly lower in the prefrail group than in the non-frail group (both p < 0.001). Numbers of criteria in FFP were significantly and inversely associated with GS (p < 0.001). GS ≤ 0.8 m/s showed the best test accuracy for frailty, with a sensitivity of 0.99, specificity of 0.37, positive predictive value of 0.76 and negative predictive value of 0.93.Conclusions The present study assessed that over 90% of elderly seeking formal assistance for the first time were either frail or prefrail. This indicates that screening for frailty should be considered for this population in order to enable action to prevent or delay disability. Further, our results indicate that GS with a cut-off at ≤ 0.8 m/s may represent a feasible and easy-to-use screening tool for detecting frailty in this population.


2020 ◽  
Vol 23 (2) ◽  
pp. 164-170
Author(s):  
Dipankar Lodh ◽  
Islam Nazmul ◽  
Talukder Debesh ◽  
Majumder Rita ◽  
Arafat Shahriar ◽  
...  

Background: CT imaging of nose and paranasal sinuses is to confirm the diagnosis, localize the disease, characterize the extent of pathology and describe any anatomical variations. A careful histopathological examination (HPE) is nesessary to decide the nature of a specific lesion. Objective: To observe performance of CT scan as a sensitive modality in the diagnosis of sinonasal mass by comparing with the findings of histopathological examination. Methods: This cross sectional study in Dhaka Medical College Hospital (DMCH). From 01/ 07/2013 to 30/06/2014 (One year), 42 patients were selected. Resuls: Here male and female ratio was found 1.4:1 So, the incidence of sinonasal growth slightly higher in male (59.3%) compared to the female (40.6%).Incidence of malignant tumour was found more in age group above 60 years. Out of 32 patients, 6 patients (18.7%) were diagnosed histopathologically as infective, 7 patients (21.8%) were benign and 19 patients (59%) had malignant sinonasal mass. Bangladesh J Otorhinolaryngol; October 2017; 23(2): 164-170


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