scholarly journals Role of CT (Computed Tomography) in the Evaluation of Fungal Diseases in Paranasal Sinus

2014 ◽  
Vol 31 (4) ◽  
pp. 189-193
Author(s):  
T Islam ◽  
SA Azad ◽  
ME Karim ◽  
L Khondker ◽  
K Rahman

A cross sectional study carried out with patients having suspected paranasal sinus (PNS) mass during January 2009 to October 2010 to evaluate the fungal diseases in PNS by computed tomographic(CT) image and comparison of the findings of this modality with histopathological result. Among the total 76 patients, the mean age of the patients was 35.95 ± 18.24 and common complaints of the patients were nasal obstruction (73.7%) and maximum 53.9% patients had PNS mass in maxillary sinuses. Out of all cases 10 were diagnosed as having fungal infection/mass by CT scan and confirmed by histopathological evaluation. Two cases were diagnosed as having fungal infection/mass by CT scan but not confirmed by histopathological findings. Of 64 cases of other than fungal infection/mass, which were diagnosed by CT scan, six were confirmed as having fungal infection/mass and 58 were other than having fungal infection/mass by histopathology. Sensitivity of CT scan to diagnose fungal infection/mass was 62.5%, specificity 96.7%, positive predictive value 83.3%, negative predictive value 90.6% and accuracy 89.5%. CT scan of the fungal diseases in paranasal sinus provides more information and better image quality and CT diagnosis correlate well with the findings of histopathology. DOI: http://dx.doi.org/10.3329/jbcps.v31i4.21002 J Bangladesh Coll Phys Surg 2013; 31: 189-193

2014 ◽  
Vol 41 (2) ◽  
pp. 27-30 ◽  
Author(s):  
T Islam ◽  
M Rahman ◽  
S Nabi ◽  
L Khondker ◽  
S Sultana

Computed tomography (CT) is the gold standard for exact delineation of paranasal sinus(PNS) disease. There are many radiologically important diseases of paranasal sinuses. Objective of the study was to evaluate the role of computed tomographic image(CT) in the diagnosis of nasopharyngeal angiofibroma. A cross sectional study was carried out in the department of Radiology & Imaging, Bangabandhu Sheikh Mujib Medical University(BSMMU), Dhaka in collaboration with department of Otolaryngology and department of Pathology of BSMMU. This study was carried out with patients having suspected PNS mass and the duration of the study was from January 2009 to October 2010. Maximum 30.3% patients were belonged to 46 to 60 years age group and of them maximum 73.7% had complaints of nasal obstruction. Maximum 53.9% patients had PNS mass in maxillary sinuses and out of all cases 8 were diagnosed as having nasopharyngeal angiofibroma by CT scan and confirmed by histopathological evaluation. Two cases were diagnosed as having nasopharyngeal angiofibroma by CT scan but not confirmed by histopathological findings. By CT evaluation total 66 cases were diagnosed as having other than nasopharyngeal angiofibroma and confirmed by histopathology. Sensitivity of CT scan to diagnose nasopharyngeal angiofibroma was 100.0%, specificity 97.1 %, positive predictive value 80.0%, negative predictive value 100.0% and accuracy 97.4%. In conclusion, CT scan of the nasopharyngeal angiofibroma in para nasal sinus provides more information and better image quality and CT diagnosis correlate well with the findings of histopathology. DOI: http://dx.doi.org/10.3329/bmj.v41i2.18801 Bangladesh Medical Journal 2012 Vol. 41 No. 2: 27-30


KYAMC Journal ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 3-8
Author(s):  
Momotaj Begum ◽  
Sabina Yiasmeen ◽  
Mahmud Hossain ◽  
Shafi Ahmed ◽  
Salahuddin Al Azad ◽  
...  

Background. Cerebral palsy is one of the common childhood neurological problem which occurs due to defect or lesion in immature brain. The worldwide incidence of cerebral palsy is approximately 2-2.5 per 1000 live births. There have been many works on the role of computed tomography scan in the diagnosis of cerebral palsy. Objective: The objective information available from careful review of imaging information such as CT brain scans, is an important adjunct to clinical data. Materials and Methods: This cross sectional study was carried out in the department of Radiology and Imaging, BSMMU and department of Paediatric Neurology unit over a period of 12 months from January 2019 to December 2019. We calculated the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of CT scan in diagnosis of CP in children. Results: This cross sectional study was carried out on consecutively selected 94 children below 15 years having clinical evidence of cerebral palsy. Among the study subjects 86.2% were diagnosed as cerebral palsy through CT scan. Conclusion: The sensitivity and specificity of CT scan of present study was found to be quite high in children which suggests a CT scan as an effective investigation for the diagnosis of cerebral palsy. KYAMC Journal Vol. 11, No.-1, April 2020, Page 3-8


2019 ◽  
Vol 9 (2) ◽  
pp. 24-31
Author(s):  
Elina Shrestha ◽  
Narayan Bikram Thapa ◽  
Shankar Bahadur Singh Rajbhandari

Introduction: Proptosis is defined as bulging of eye anteriorly out of the orbit. Our main objective was to analyze the pattern of computerised tomographic findings in evaluation of proptosis. Computerised tomography (CT) is noninvasive, easily accessible, affordable and reliable imaging which helps in early diagnosis and prompt treatment. Methods: A descriptive cross sectional study of total 58 patients presenting with proptosis referred to our department of radiology for computerised tomography evaluation during one year period were undertaken into study. The clinical information provided by ophthalmologist also helped our study to derive into conclusion. SPSS version 20 software was used for statistical data analysis. Results: Out of 58 patients, the most common cause of proptosis was neoplasm constituting of 25 cases (43.1%). Retinoblastoma was the commonest orbital tumor. Out of remaining cases, 15 (25.8%) were infective, 14 (24.1%) were inflammatory, two (3.44%) were traumatic and remaining two cases (3.44%) had no definitive cause for proptosis. Bilateral proptosis was commonly associated with thyroid ophthalmopathy. Among the subjects 32 were male, 26 were female. Male: Female ratio was 1:1.23. Age group was ranging from 1 month to 73 years.Mean age was 26.4 ± 22 years. Conclusions: Computerised tomography has an important role in distinguishing the different types of lesions based on their characteristics, location and extension prior to undertaking definitive surgical and medical treatment. Overall accuracy of CT in our study was 81%, sensitivity of 82.6%, specificity of 80.6%, positive predictive value of 76% and negative predictive value of 86.2%.


2020 ◽  
pp. 1-2
Author(s):  
Bhanupriya Singh ◽  
Khushal N Pawar ◽  
Suhas S Ghule ◽  
Dilip L Lakhkar

Background: More than 80% of all primary hepatic malignancies are hepatocellular carcinoma. Identification of a liver lesion depends on the attenuation difference between normal liver and the lesion. CT helps in detecting tumors and their size in liver quiet successfully. Accurate detection of liver mass is crucial for the deciding the treatment regimens. Objective: The study was undertaken to compare the results of CT-scan to histopathology findings. Methodology: This cross-sectional study was carried out in the Department of Radiodiagnosis and Imaging, Dr. Vitthalrao Vikhe Patil Foundation’s Medical College, Ahmednagar in association with Department of pathology of the concerned institute for histopathological diagnosis from 01-03-2014 to 28-02-2015 for a period of one year. Patients having hepatic mass of any sex or age presenting in the hospital were included in the study. The exclusion criteria were as patients refusing consent, or CT-scan and/or biopsy, known adverse reaction to contrast agent. CT scan and histopathology were done in all the subjects. Result: 50 subjects were studied in this study. Mean age of all subjects was 52.88 ± 16.03 years with a range of 18 year to 85 years. 40 cases were male in the study group. Maximum number of cases were in the age group 40-59 years. Out of 28 confirmed malignant cases by histopathology, 27 cases were diagnosed as malignant by CT scan too. Sensitivity of CT to diagnose malignant lesion was 96.4%, specificity 86.4%, accuracy 92%, positive predictive value 90% and negative predictive value 95%. Conclusion: CT scan can be used as a tool for the detecting of malignant liver masses.


2018 ◽  
Vol 7 (2) ◽  
pp. 17-23
Author(s):  
- Mukthadira ◽  
MutaTah Hira ◽  
Netay Kumer Sharma ◽  
ASM Mahbubur Rahman ◽  
MA Razzaque ◽  
...  

Uterine fibroids, also known as leiomyomas, are the most common uterine neoplasms. Although benig, they can be associated with a significant number of morbidity and are the most common indication for hysterectomy. Transvaginal ultrasonography (TVS) has become essential in the diagnosis and management of the uterine fibroids. TVS provides a detailed examination of uterus and ovaries. However, there is no nation-wide and regional clinical study on the use of TVS for the evaluation of uterine fibroids in Bangladesh. In this work, a cross-sectional study toob serve the role of TVS in the evaluation of uterine fibroids in a region of Bangladesh (Greater Mymensingh). In the diagnosis of uterine fibroids by TVS, we observed that 35(81.4%) cases (out of 43) are fibroids and 8 (18.6%) cases are non-fibroids. In histopathological diagnosis, we found 36 (83.7%) cases are uterine fibroids, and 7 (16.3%) cases are without fibroids. In this study, TVS diagnosed uterine fibroids with a sensitivity of 94.4%, the specificity of 85.71%, the accuracy of 97.6%, the positive predictive value of 97.1% and negative predictive value of 75%. The results demonstrate that TVS has the potential to become a useful imaging tool for the evaluation of uterine fibroids. CBMJ 2018 July: Vol. 07 No. 02 P: 17-23


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Hossein Abdolrahimzadeh Fard ◽  
Salahaddin Mahmudi-Azer ◽  
Sepideh Sefidbakht ◽  
Pooya Iranpour ◽  
Shahram Bolandparvaz ◽  
...  

Background. The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT  scan as a screening measure of COVID-19 in trauma patients. Methods. This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT scans were evaluated in a blinded manner, and the main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two Radiological Society of North America (RSNA) categories with the highest probability of COVID-19 pneumonia (i.e., typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID-19 pneumonia into “negative CT scan group.” Results. Chest CT scan had a sensitivity of 68%, specificity of 56%, positive predictive value of 34.8%, negative predictive value of 83.7%, and accuracy of 59.3% in detecting COVID-19 among trauma patients. Moreover, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals, a sensitivity of 100%, specificity of 66.7%, and negative predictive value of 100% were obtained ( p value: 0.05). Conclusion. Findings of the study indicated that the CT scan’s sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 compared with nontraumatic people.


2016 ◽  
Vol 6 (1) ◽  
pp. 33
Author(s):  
Tahmina Islam ◽  
Salauddin Al-Azad ◽  
Lubna Khondker ◽  
Sabina Akhter

<p><strong>Background:</strong> Computed tomography (CT) is the gold standard for exact delineation of paranasal sinus(PNS) disease. There are many radiologically important diseases of paranasal sinuses.<strong> </strong></p><p><strong>Objective:</strong> to evaluate the malignant PNS mass by computed tomographic image and the findings of this modality were compared with histopathological result.</p><p><strong>Methods:</strong> It was a cross sectional type of study and carried out with suspected PNS mass having patients during January 2009 to Octo­ber 2010.</p><p><strong>Results:</strong> The mean age of the patients was 35.95 ± 18.24 and common complaints of the patients were nasal obstruction (73.7%) and maximum 53.9% patients had PNS mass in maxillary sinuses. Out of 76 cases 21.1 % found malignant mass on CT and after histopathology 19. 7% had malignant mass. Out of all cases 14 were diagnosed as malig­nant PNS mass by CT scan and confirmed by histopathological evaluation and they were true positive. Two cases were diagnosed as malignant PNS mass by CT scan but not confirmed by histopathological findings and they were false positive. Of 60 cases, which were diagnosed by CT scan, one was confirmed as malignant and 59 were benign by histopa­thology. They were false negative and true negative respectively. Sensitivity of CT scan to diagnose malignant PNS mass was 93.3%, specificity 96.7%, positive predictive value 87.5%, negative predictive value 98.3% and accuracy 96.1 %.<strong> </strong></p><p><strong>Conclusion:</strong> CT scan of the malignant para nasal sinus mass provides more information and better image quality and CT diagnosis correlate well with the findings of histopathology.</p>


2018 ◽  
Vol 5 (6) ◽  
pp. 1450
Author(s):  
Jyothi S. M. ◽  
Santosh U. Karpur

Background: All suspected cases of acute pancreatitis should undergo CT scan. It is non invasive and reliable. CT scan is able to give complete picture of acute pancreatitis. The objective of the presentMethods: The present study was hospital based. 60 cases with evidence of acute pancreatitis were included. They were studied for 3 years from June 2015 to May 2018. CT scan was performed in all cases. CT features of the pancreas were noted and described.Results: Acute pancreatitis incidence was four times more in males compared to females i.e. 80% vs. 20%. CT scan showed that pancreatic gland was normal only in 16.7% of the cases. The contour was irregular in 66.7% of the cases. Eight cases showed necrosis. Less than 30% three patients (10%) had grade A acute pancreatitis. 28 cases were showing Phlegmonous changes. In 24 cases it was observed that lesser sac was affected.Conclusions: Authors conclude that for grading and staging of the pancreatitis of acute nature, CT scan is must and is very helpful to the clinicians. CT scan helps not only in precise diagnosis but also in predicting the proper prognosis of the patients who are affected by the pancreatitis of acute in nature.


2012 ◽  
Vol 27 (2) ◽  
pp. 125-131 ◽  
Author(s):  
Hanan H. Soliman ◽  
Hala Nagy ◽  
Nesreen Kotb ◽  
Mohamed A. Alm El-Din

Background and aim To evaluate the role of chemokine CC ligand 20 (CCL20) as a biomarker for hepatocellular carcinoma (HCC). Patients and methods Ninety patients in four groups were enrolled in this prospective cross-sectional study: 30 with HCC (group I), 30 with liver cirrhosis (group II), 15 with hepatitis C virus infection (group III), and 15 healthy blood donors as controls. Alpha fetoprotein (AFP), CCL20 and vascular endothelial growth factor (VEGF) were measured in all groups. Results Serum levels of CCL20 were significantly different among the study groups (F=230.979, p<0.001). The highest level was found in HCC patients (57.305 ± 6.386 pg/mL) followed by patients with cirrhosis (45.999 ± 5.165 pg/mL) compared with 22.781 ± 5.986 pg/mL and 18.585 ± 3.554 pg/mL in asymptomatic patients with HCV infection and controls, respectively. In HCC patients, CCL20 significantly correlated with VEGF (r=0.559, p=0.001), AFP (r=0.814, p<0.001), Child score (r=0.748, p<0.001), and tumor size (r=0.825, p<0.001). The cutoff value of CCL20 for the detection of HCC in HCV-infected patients was 54 pg/mL with 93.1% accuracy, 89.6% negative predictive value, 92.6% positive predictive value, 83.3% sensitivity, and 93.3% specificity. In patients with cirrhosis, CCL20 significantly correlated with VEGF (r=0.455, p=0.011), AFP (r=0.975, p<0.001), and Child score (r=0.977, p<0.001). Conclusion CCL20 may be used for the detection of HCC in HCV-infected patients with comparable specificity and higher sensitivity than AFP.


2020 ◽  
Author(s):  
Hossein Abdolrahimzadeh Fard ◽  
Salahaddin Mahmudi-Azer ◽  
Sepideh Sefidbakht ◽  
Pooya Iranpour ◽  
Shahram Bolandparvaz ◽  
...  

Abstract Purpose: The lack of enough medical evidence about COVID-19 regarding optimal prevention, diagnosis, and treatment contributes negatively to the rapid increase in the number of cases globally. A chest computerized tomography (CT) scan has been introduced as the most sensitive diagnostic method. Therefore, this research aimed to examine and evaluate the chest CT scan as a screening measure of COVID-19 in trauma patients.Methods: This cross-sectional study was conducted in Rajaee Hospital in Shiraz from February to May 2020. All patients underwent unenhanced CT with a 16-slice CT scanner. The CT-scans were evaluated in a blinded manner and main CT scan features were described and classified into four groups according to RSNA recommendation. Subsequently, the first two RSNA categories with the highest probability of COVID pneumonia (i.e. typical and indeterminate) were merged into the “positive CT scan group” and those with radiologic features with the least probability of COVID pneumonia into “negative CT scan group”.Results: Chest CT scan had a sensitivity (68%), specificity (56%), positive predictive value (34.8%), negative predictive value (83.7%), and accuracy (59.3%) in detecting COVID-19 among trauma patients. Also, for the diagnosis of COVID-19 by CT scan in asymptomatic individuals a sensitivity of 100% and a specificity of 66.7% and a negative predictive value of 100% was obtained.Conclusion: Findings of the study indicated that the CT scan's sensitivity and specificity is less effective in diagnosing trauma patients with COVID-19 in comparison to non-traumatic people.


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