scholarly journals A familial case of von Hippel-Lindau disease associated with spinal cord hemangioblastoma and syringomyelia: surgical treatment and dynamic monitoring

2021 ◽  
Vol 9 (1) ◽  
pp. 119-125
Author(s):  
R.S. Levin ◽  
◽  
E.V. Zaklyazminskaya ◽  
M.N. Aslanukov ◽  
S.K. Oshepkov ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Surgical Treatment ◽  
Dynamic Monitoring ◽  
Familial Case ◽  
Von Hippel Lindau ◽  
Von Hippel Lindau Disease

Monotherapy with thalidomide for treatment of spinal cord hemangioblastomas in a patient with von Hippel-Lindau disease

2009 ◽  
Vol 53 (3) ◽  
pp. 464-467 ◽  
Author(s):  
Iacopo Sardi ◽  
Massimiliano Sanzo ◽  
Flavio Giordano ◽  
Anna Maria Buccoliero ◽  
Federico Mussa ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Von Hippel Lindau ◽  
Von Hippel Lindau Disease

scholarly journals Resection of spinal hemangioblastoma

2014 ◽  
Vol 37 (v2supplement) ◽  
pp. Video15
Author(s):  
Giuseppe Lanzino ◽  
Saul F. Morales-Valero ◽  
William E. Krauss
Keyword(s):  
Spinal Cord ◽  
Venous Drainage ◽  
Complete Resection ◽  
Cervical Cord ◽  
Von Hippel Lindau ◽  
Link Type ◽  
Single Piece ◽  
Von Hippel Lindau Disease ◽  
Spinal Hemangioblastoma

Spinal cord hemangioblastomas occur as sporadic lesions or in the setting of Von Hippel-Lindau disease. In this intraoperative video we present a case of sporadic cervical cord hemangioblastoma and illustrate the main surgical steps to achieve safe and complete resection which include: identification and division of the feeding arteries; careful circumferential dissection of the tumor from the surrounding gliotic cord; identification, isolation and division of the main venous drainage and single piece removal of the tumor.The video can be found here: http://youtu.be/I7DxqRrfTxc.

scholarly journals Surgical treatment of von Hippel-Lindau disease complicated by retinal detachment: a clinical case

2018 ◽  
Vol 11 (1) ◽  
pp. 85-92
Author(s):  
V.V. Neroev ◽  
◽  
P.A. Ilyukhin ◽  
M.V. Ryabina ◽  
A.Yu. Novikova ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Retinal Detachment ◽  
Clinical Case ◽  
Von Hippel Lindau ◽  
Von Hippel Lindau Disease

scholarly journals Spinal Cord Hemangioblastomas in von Hippel-Lindau Disease: Management of Asymptomatic and Symptomatic Tumors

2012 ◽  
Vol 53 (6) ◽  
pp. 1073 ◽  
Author(s):  
Tae Yup Kim ◽  
Do Heum Yoon ◽  
Hyun Chul Shin ◽  
Keung Nyun Kim ◽  
Seong Yi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Disease Management ◽  
Von Hippel Lindau ◽  
Von Hippel Lindau Disease

scholarly journals Von Hippel-Lindau Disease with Multiple Spinal Cord Hemangioblastomas, Syringomyelia and Pheochromocytoma.

1995 ◽  
Vol 34 (3) ◽  
pp. 216-219 ◽  
Author(s):  
Hisashi FURUSU ◽  
Hidenori MATSUO ◽  
Kazuhiko NAKAO ◽  
Yasuo UEDA ◽  
Wataru AOI
Keyword(s):  
Spinal Cord ◽  
Von Hippel Lindau ◽  
Von Hippel Lindau Disease

Microsurgical Resection of Spinal Cord Hemangioblastomas

2005 ◽  
Vol 57 (suppl_4) ◽  
pp. ONS-372-ONS-376 ◽  
Author(s):  
Russell R. Lonser ◽  
Edward H. Oldfield
Keyword(s):  
Spinal Cord ◽  
Blood Loss ◽  
Benign Tumors ◽  
Intramedullary Spinal Cord ◽  
Von Hippel Lindau ◽  
Spinal Cord Neoplasms ◽  
Von Hippel Lindau Disease ◽  
Microsurgical Resection

Abstract HEMANGIOBLASTOMAS ARE NOT uncommon intramedullary spinal cord neoplasms. They are highly vascular, benign tumors that occur either sporadically or in the presence of von Hippel-Lindau disease. Despite their exceptionally vascular nature, these lesions can consistently be resected completely and safely with minimal blood loss. We describe a microsurgical method for removal of these tumors from the spinal cord.

Hemangioblastoma

2018 ◽  
Author(s):  
Jeffrey Hatef ◽  
Russell R. Lonser
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Cyst Formation ◽  
Complete Resection ◽  
Central Nervous System Tumors ◽  
Clinical Imaging ◽  
Nervous System Tumors ◽  
Von Hippel Lindau ◽  
Von Hippel Lindau Disease

Hemangioblastomas are benign central nervous system tumors that are found primarily (99%) in the cerebellum, brainstem, and spinal cord. They can occur sporadically (67% of cases) or in the context of the familial neoplasia syndrome, von Hippel-Lindau disease (VHL; 33%). These lesions often remain quiescent or grow in a saltatory pattern. When these tumors cause signs or symptoms, the signs or symptoms are often associated with peritumoral cyst formation. Whether the tumor occurs sporadically or in the context of VHL, complete resection is the treatment of choice when necessary. This chapter describes the clinical, imaging, and treatment features of this neoplasm.

Continuous angiogenesis inhibition in the treatment for von Hippel–Lindau-related hemangioblastomas of retina and spinal cord

2019 ◽  
Vol 25 (8) ◽  
pp. 2049-2051 ◽  
Author(s):  
Derya Kıvrak Salim
Keyword(s):  
Spinal Cord ◽  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Therapeutic Option ◽  
Suppressor Gene ◽  
Vascular Endothelial ◽  
Pediatric Age ◽  
Von Hippel Lindau ◽  
Von Hippel Lindau Disease ◽  
Endothelial Growth Factor

Hemangioblastomas of central nervous system are rare and indolent. Twenty-five percent of cases are in association with von Hippel–Lindau disease. Surgery is the standard therapy but un-resectable or recurrent cases need radiation or systemic therapy. Defective von Hippel–Lindau tumor suppressor gene leads to vascular endothelial growth factor overexpression and enhance angiogenesis. Here we report a 19-year-old male, diagnosed at pediatric age, who had retinal and spinal cord hemangioblastomas. He was treated 34 months with bevacizumab, afterwards 12 months with thalidomide and tertiary therapy with pazopanib for 9 months which still goes on. In case of need, radiation and surgical procedures were performed. Vascular endothelial growth factor inhibition continuity is a good therapeutic option, which improves outcomes of von Hippel–Lindau-related hemangioblastomas.

Sign in / Sign up

Export Citation Format

Share Document