scholarly journals UV-protective Properties of Topical of Astaxanthin Half side Controlled Pilot Study

Background: Astaxanthin, a product of green algae, a naturally occurring reddish pigment from the carotenoid group, is known as a potent antioxidant reducing free radicals. Objective: The aim of this pilot clinical study is to determine whether astaxanthin in topical formulation has antiinflammatory and uv-protective Properties through its antioxidant potency. Material and Methods: The UV-protective effect of Astaxanthin AstaCos® OL50 versus a placebo tested in a half side controlled setting on 21 healthy volunteers Fitzpatrick skin type 2 or 3. A light testing system was used for irradiation of volar aspects of both forearms, one with Astaxanthin formulation, the other with placebo. Twenty four hours later photodocumentation and colormetric measurement of erythema values in all treated areas was performed. Results: After equal uv-exposure, the erythema value after 24 hours on the astaxanthin side is on average 25% lower than on the placebo side. Astaxanthin suppresses visual erythema formation in over 71.42% of cases. Discussion: Uv-exposure causes inflammation, accelerated skin aging and non melanoma skin cancer. Topical Astaxanthin reducing the inflammatory effects of uv-irradiation could prevent later stages of photoaging and malignant skin disease. Zusammenfassung Hintergrund: Astaxanthin, ein Produkt aus Grünalgen, ein natürlich vorkommendes rötliches Pigment aus der Gruppe der Carotinoide, ist als starkes Antioxidans bekannt, das freie Radikale reduziert. Zielsetzung: Das Ziel dieser klinischen Pilotstudie ist es, festzustellen, ob Astaxanthin in topischer Formulierung durch seine antioxidative Potenz uv-protektive Effekte hat. Material und Methoden: Die UV-schützende Wirkung von Astaxanthin AstaCos® OL50 im Vergleich zu einem Placebo wurde in einer halbseitigen kontrollierten Einstellung an 21 gesunden Probanden mit Fitzpatrick-Hauttyp 2 oder 3 getestet. Mit einem Lichttestsystem wurden die volaren Seiten beider Unterarme bestrahlt, einer mit der Astaxanthin-Formulierung, der andere mit Placebo. 24 Stunden später erfolgten Fotodokumentation, farbmetrische Messung der Erythemwerte in allen behandelten Bereichen. Ergebnisse: Nach gleicher uv-Belichtung ist der Erythemwert nach 24 Stunden auf der Astaxanthin-Seite im Durchschnitt 25% niedriger als auf der Placebo-Seite. Astaxanthin unterdrückt die visuelle Erythembildung in über 71,42% der Fälle. Diskussion: Uv-Exposition verursacht Entzündungen, beschleunigte Hautalterung und Nicht-Melanom-Hautkrebs. Die topische Anwendung von Astaxanthin, das die entzündlichen Effekte der UV-Bestrahlung reduziert, könnte spätere Stadien der Lichtalterung und bösartige Hauterkrankungen verhindern.

Polymers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1188
Author(s):  
Klara Kostajnšek ◽  
Krste Dimitrovski

The paper presents an extension of existed cover factor theory more suitable for the evaluation of light penetration through a net woven fabrics structure. It also introduces a new simplified model of predicting the ultraviolet (UV) protective properties of woven fabrics assuming that the coefficient of reflection (KR), transmission (KT), and absorption (KA) of constitutive yarns are known. Since usually they are not, the procedure of preparation of simulation of proper woven fabric samples without interlacing and with known constructional parameters is also presented. The procedure finishes with a fast and cheap detection of missed coefficient for any type of yarns. There are differences between theoretical and measured results, which are not particularly significant in regard to the purpose and demands of investigation.


2012 ◽  
Vol 87 (2) ◽  
pp. 212-219 ◽  
Author(s):  
Pedro Andrade ◽  
Maria Manuel Brites ◽  
Ricardo Vieira ◽  
Angelina Mariano ◽  
José Pedro Reis ◽  
...  

BACKGROUND: Non-melanoma skin cancer, a common designation for both basal cell carcinomas and squamous cell carcinomas, is the most frequent malignant skin neoplasm. OBJECTIVE: Epidemiologic characterization of the population with Non-melanoma skin cancer. METHODS: Retrospective analysis of all patients diagnosed with Non-melanoma skin cancer based on histopathologic analysis of all incisional or excisional skin biopsies performed between 2004 and 2008 in a Department of Dermatology. RESULTS: A total of 3075 Non-melanoma skin cancers were identified, representing 88% of all malignant skin neoplasms (n=3493) diagnosed in the same period. Of those, 68,3% were basal cell carcinomas. Most Non-melanoma skin cancer patients were female and over 60 years old. Of all Non-melanoma skin cancer, 81,7% (n=1443) were located in sun-exposed skin, and represented 95,1% of malignant skin neoplasms in sun-exposed skin. Non-melanoma skin cancer was the most frequent malignant skin neoplasm in most topographic locations, except for abdomen and pelvis - over 95% of all malignant skin neoplasms in the face, neck and scalp were Non-melanoma skin cancer. Basal cell carcinomas were clearly predominant in all locations, except in upper and lower limbs, lower lip and genitals, where squamous cell carcinomas represented respectively 77,7%, 77,4%, 94,7% and 95,3% of the Non-melanoma skin cancers. CONCLUSION: Being the most common skin cancer, Non-melanoma skin cancer should be under constant surveillance, in order to monitor its epidemiologic dynamics, the efficiency of preventive measures and the adaptation of the healthcare resources.


2015 ◽  
Vol 80 (5) ◽  
pp. 705-715 ◽  
Author(s):  
Milica Milosevic ◽  
Ana Krkobabic ◽  
Marija Radoicic ◽  
Zoran Saponjic ◽  
Vesna Lazic ◽  
...  

The possibility of in situ photoreduction of Ag+ ions using colloidal TiO2 nanoparticles deposited on the surface of polyamide fabric in the presence of amino acid alanine and methyl alcohol is discussed. The presence of TiO2/Ag nanoparticles on the polyamide fabric was confirmed by FESEM and ICP analyses. Antibacterial activity of the fabric was tested against Gram-negative bacterium Escherichia coli and Gram-positive bacterium Staphylococcus aureus. Fabricated TiO2/Ag nanoparticles on the surface of polyamide fabric provided maximum bacterial reduction and thus, excellent antibacterial activity. In spite of silver leaching from the fabric during washing, impregnated polyamide fabric preserved maximum reduction of Escherichia coli colonies. Antibacterial activity against Staphylococcus aureus slightly decreased after ten washing cycles, but still antibacterial activity can be considered as satisfactory. In addition, the presence of TiO2/Ag nanoparticles ensured better UV protection efficiency which belongs to very good UV protection category.


2011 ◽  
Vol 38 (8) ◽  
pp. 53-59
Author(s):  
A.A. Ol'khov ◽  
M.A. Gol'dshtrakh ◽  
A.A. Krutikova ◽  
A.A. Ishchenko ◽  
D. Dzh. Liao ◽  
...  

2007 ◽  
Vol 15 (4) ◽  
pp. 366-372 ◽  
Author(s):  
X.X. Feng ◽  
L.L. Zhang ◽  
J.Y. Chen ◽  
J.C. Zhang

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