scholarly journals Colorectal Carcinoma with Metastasis to Oral Mucosa; Two Cases Report

2020 ◽  
Vol 4 (1) ◽  
Keyword(s):  
Soft Tissue ◽  
Poor Prognosis ◽  
Colorectal Adenocarcinoma ◽  
Soft Tissues ◽  
Metastatic Tumour ◽  
History Taking ◽  
Jaw Bones ◽  
Oral Malignancies ◽  
Oral Metastasis

Oral metastasis of tumours is known to cause 1% of all oral malignancies and is most often the result of a primary in lung, breast and kidney [1,2]. The location of the metastasis is usually the jaw bones as opposed to soft tissues. A metastasis from colorectal adenocarcinoma to the soft tissues is hence extremely infrequent. The gingivae (55%) followed by the tongue (30%) are the most common soft tissue sites affected by metastatic tumour in the mouth [3]. The diagnosis of such cases is dependent on adequate history taking and although has a poor prognosis but early detection and effective treatment are necessary to aid in treatment and follow up. Here we report two cases of colorectal adenocarcinoma that metastasized to the oral gingiva and were diagnosed by histology and supportive immunohistochemistry.

scholarly journals PEComa of soft tissues can mimick lymph node relapse in patients with history of testicular seminoma

2013 ◽  
Vol 7 (9-10) ◽  
pp. 651 ◽  
Author(s):  
Gabriele Guglielmetti ◽  
Paolo De Angelis ◽  
Paolo Mondino ◽  
Carlo Terrone ◽  
Alessandro Volpe
Keyword(s):  
Lymph Node ◽  
Soft Tissue ◽  
Soft Tissues ◽  
Percutaneous Biopsy ◽  
Surgical Excision ◽  
Pelvic Lymphadenectomy ◽  
Adjuvant Radiation ◽  
Soft Tissue Neoplasm ◽  
Testicular Seminoma

Perivascular Epithelioid Cell tumour (PEComa) is rare. We describe a 39-year-old man who underwent a left radical orchidectomy and adjuvant radiation therapy for a stage IA classical testicular seminoma. He was diagnosed with a mass lateral to the right common iliac artery that was considered suspicious for late lymph node relapse after 3 years of follow-up. Due to the unusual location of the mass and the equivocal findings of percutaneous biopsy, a laparoscopic pelvic lymphadenectomy was performed. Final pathology revealed PEComa of soft tissue. The patient is disease free after 38 months of follow-up without adjuvant treatment. The presence of rare soft-tissue neoplasm should be considered in differential diagnosis of retroperitoneal masses during follow-up of germ cell tumours. Suspicious isolated recurrences of these neoplasms in unusual locations can require surgical excision to confirm diagnosis and avoid inappropriate treatment.

Early Composite Cranioplasty in Infants with Severe Aplasia Cutis Congenita: A Report of Two Cases

2005 ◽  
Vol 42 (4) ◽  
pp. 442-447 ◽  
Author(s):  
Emilia A. Ploplys ◽  
Arshad R. Muzaffar ◽  
Joseph S. Gruss ◽  
Richard G. Ellenbogen
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Cranial Bone ◽  
Soft Tissue Coverage ◽  
Calvarial Bone ◽  
Aplasia Cutis Congenita ◽  
Skull Defects ◽  
Graft Donor ◽  
Cutis Aplasia

Objective Severe cutis aplasia congenita has traditionally been treated with initial soft tissue coverage and delayed cranioplasty. We advocate the technique of early composite reconstruction of both bone and soft tissues. Methods Two cases of cutis aplasia congenita with large skull defects (6 × 10 cm, 8 × 8 cm) of superficial layers, skull, and dura are presented. In each case, composite reconstruction was undertaken before 2 weeks of age with restoration of bony and soft tissue coverage through autologous, full-thickness cranial bone grafts and scalp flaps. Both children have been followed up over 2 years with clinical examination and computed tomography (CT) scans. Results In both cases, defects were completely repaired postoperatively and remained closed 2 years later. Complete regeneration of calvarial bone graft donor sites were documented by CT scan. Head shape and circumference were normal at 2-year follow up.

scholarly journals Neglected сlubfoot treated by Ilizarov and Ponseti methods

2021 ◽  
Vol 27 (3) ◽  
pp. 361-365
Author(s):  
M.M. Chaudhary ◽  
◽  
I.M. Chaudhary ◽  
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Ponseti Method ◽  
Previous Surgery ◽  
Excessive Pressure ◽  
Full Correction ◽  
Ilizarov Fixator ◽  
The Moment ◽  
Tissue Tension

The Ponseti method has revolutionized clubfoot treatment. Though completely neglected clubfeet are now rare, partially or incompletely and improperly treated feet are not uncommon. Relapses after successful correction may occur due to non-compliance with bracing. In scarred soft tissues due to previous surgery, soft tissue distraction using external fixation helps achieve correction. The Ilizarov fixator permits us to follow the Ponseti protocol, using correction methods that may either be constrained or unconstrained by hinges. Applying force vectors perpendicular to the moment arm allows us to correct the еquinus without damaging the ankle joint. All of the above is possible when the talus is round. Full correction of the deformity is possible. However, longterm follow-up of these patients has revealed stiffness of the ankle setting and frequently with tibio-talar osteophytes anteriorly. They are probably a reaction to excessive pressure developed in the joint due to the tight soft tissues. Hence the author has now added a mild shortening of the tibia and fibula to reduce soft tissue tension, rather than resorting to further soft tissue releases through scarred tissues. This allows faster correction with the Ponseti-Ilizarov protocol and allows good ankle range of motion to persist.

scholarly journals The Correlation between Follow-up MRI Findings and Laboratory Results in Pyogenic Spondylodiscitis

2020 ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Imaging Method ◽  
Mri Findings ◽  
Pyogenic Spondylodiscitis ◽  
Tissue Responses ◽  
Laboratory Results ◽  
Tissue Changes ◽  
Soft Tissue Changes

Abstract Background Although MRI is the gold-standard imaging method in the diagnosis of spondylodiscitis, role of follow-up imaging is debated and there can be discrepancies with regard to the significance of bony or soft tissue responses to treatment. Purpose of our study is to test whether the MRI changes on follow-up imaging correlate with laboratory findings of treatment response. Methods A total of 48 patients with pyogenic spondylodiscitis who underwent baseline and follow-up MRI were retrospectively reviewed. The extent of bone marrow edema, paravertebral soft tissue inflammation, and disc height were compared on baseline and follow-up MRIs with the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels obtained from the medical records at baseline and on follow-up. Relationships between the MRI and laboratory changes were analyzed using the Spearmann correlation test. Results The mean MRI follow-up period was 42.25 days. Based on the CRP (resolved: n=19, resolving: n=19, and aggravated: n=10), there was significant correlation between the laboratory results and the changes in the bone and soft tissues (p < 0.01, both). The correlation was best with soft tissue changes (rho: 0.48) followed by bony changes (rho: 0.41). Based on the ESR (resolved: n=8, resolving: n=22, and worsened: n=18), the correlation was stronger with bone changes (rho: 0.45, p < 0.01) than it was with soft tissue changes (rho: 0.39, p = 0.01). Conclusion Follow-up MRI findings of pyogenic spondylodiscitis show variable tissue responses. CRP was best correlated with soft tissue changes, while ESR showed the best association with bony changes.

scholarly journals Clinical and radiographics results at 3 years of RCT with split-mouth design of submerged vs. nonsubmerged single laser-microgrooved implants in posterior areas

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Renzo Guarnieri ◽  
Dario Di Nardo ◽  
Gianni Di Giorgio ◽  
Gabriele Miccoli ◽  
Luca Testarelli
Keyword(s):  
Soft Tissue ◽  
Statistical Difference ◽  
Soft Tissues ◽  
Gingival Recession ◽  
Statistical Correlation ◽  
Two Stage ◽  
One Stage ◽  
Keratinized Tissue ◽  
Significant Difference

Abstract Aim To evaluate and compare radiographic crestal bone loss (CBL) and soft tissue parameters around submerged/two-stage and nonsubmerged/one-stage single implants with the same endosseous portion (body design and surface, thread design and distance) and identical intramucosal laser-microgrooved surface, after 3 years of loading. Materials and methods Twenty submerged/two-stage implants and 20 nonsubmerged/one-stage implants were placed randomly with a split-mouth design in the posterior areas of 20 partially edentulous patients. Radiographic and clinical examinations were carried out at the implant placement, at the delivery of prosthetic restorations, and at each year of the follow-up period. Plaque index (PI), probing depth (PD), bleeding on probing (BOP), and gingival recession (REC) were recorded. Radiographic crestal bone levels were assessed at the mesial and distal aspect of the implant sites. In addition, the influence of the vertical keratinized tissue thickness (KTT) on CBL was investigated. Results At the delivery of prosthetic restorations, a statistically significant difference (P = 0.013) was found in radiographic mean CBL between submerged and nonsubmerged implants (0.15 ± 0.05 mm vs. 0.11 ± 0.04 mm). At the end of the follow-up period, no statistical difference (P = 0.741) was found in the mean CBL between submerged and nonsubmerged implants (0.27 ± 04 mm vs. 0.26 ± 0.5 mm). The changes in the soft tissues including PI, PD, BOP, and REC had no significant differences in either group. Moreover, KTT did not show a statistical correlation with CBL. Conclusions After 3 years of loading, no statistical difference was noted in CBL and soft tissue conditions between single submerged two-stage and nonsubmerged one-stage laser-microgrooved implants. Trial registration http://clinicaltrials.gov/ct2/show/NCT03674762

scholarly journals Using TSF Multi-Planar External Fixation for Overcorrection of Severe Equinus Contractures of the Ankle joint

2019 ◽  
Vol 4 (4) ◽  
pp. 2473011419S0015
Author(s):  
Sherif Dabash ◽  
Eric Potter ◽  
William McGarvey
Keyword(s):  
Soft Tissue ◽  
Ankle Joint ◽  
Soft Tissues ◽  
Retrospective Chart Review ◽  
Taylor Spatial Frame ◽  
Rank Test ◽  
Tertiary Referral Center ◽  
Spatial Frame ◽  
Equinus Deformity

Category: Ankle, Hindfoot, Trauma Introduction/Purpose: Equinus deformity is a debilitating condition which interferes with the activity of daily living. Correction of the deformity ranges from conservative (heel cord stretching, orthotics) to surgical treatment (Baumann, Strayer, Achilles lengthening, soft tissue releases). Severe contractures need surgical intervention with extensive dissections to release soft tissues. This study investigated the clinical outcomes of gradual equinus contracture overcorrection using a Taylor Spatial Frame with tendo-Achilles lengthening or toe flexor tenotomy as necessary. Methods: This retrospective chart review evaluated patients with significant equinus treated with a Taylor Spatial Frame at a single large tertiary referral center. Data collected included: diagnosis; patient demographics; laterality; time in frame; additional procedures; complications. Patients were assessed preoperatively and were followed at one-week, three-week, six-week, three- month, and six-month intervals, and yearly after. Results: 24 patients (26 procedures) were treated with a Taylor Spatial Frame for equinus and had complete preoperative and eighteen-month follow-up measurements. The angle of deformity increased from a preoperative -21.5 (range, -69.0 to -1.0) degrees to a postoperative 4.9 (range, -17.0 to 17.0) degrees (z = -4.4573, p = 0.0001, N = 26, Wilcoxon signed rank test). Four complications occurred during the follow up (two pin site infections, one broken pin, and one plantar abscess). Three patients had recurrence of of equinus deformity at time of last follow-up. Conclusion: Taylor Spatial Frame is a successful method for correcting severe, fixed equinus contractures of the ankle joint with minimal soft tissue related complications. Over correction should be achieved in order to compensate for the loss of some dorsiflexion after frame removal.

scholarly journals Metastatic Tumors of the Oral Cavity

2014 ◽  
Vol 15 (2) ◽  
pp. 263-271 ◽  
Author(s):  
DS Sanketh ◽  
N Amrutha ◽  
Shankargouda Patil
Keyword(s):  
Oral Cavity ◽  
Soft Tissues ◽  
Clinical Manifestations ◽  
Metastatic Tumor ◽  
Metastatic Tumors ◽  
Jaw Bones ◽  
History Of ◽  
Metastatic Process ◽  
Conducive Environment ◽  
Oral Metastasis

ABSTRACT The pivotal reason for morbidity and mortality of any type of cancer is due to metastasis that occurs as a result of adaptation of genetically unstable cancer cells, in an ectopic conducive environment. Oral metastasis in spite of being unusual or rare represents around 25% of the first signs of metastatic spread. Literature says there are more number of cases of jaw bone metastasis reported than in the oral soft tissues. The most common primary organs metastasizing to the jaw bones and the oral soft tissues are the breast and the lungs respectively. The issue in diagnosing a metastatic tumor arises either when the patient does not reveal the history of the primary illness he or she may be suffering from or when he or she is unaware of it. Diagnosis in such situations is a challenge to the clinician or pathologist. Diagnosing any lymph node or distant metastasis from oral cancer is very important for the prognosis of the patient. In this review we have made an attempt, to explain some recent concepts of pathophysiology of the metastatic process, the clinical manifestations of metastatic tumors to the oral region and to discuss their diagnostic workup. How to cite this article Rao RS, Patil S, Sanketh DS, Amrutha N. Metastatic Tumors of the Oral Cavity. J Contemp Dent Pract 2014;15(2):263-271.

scholarly journals The Correlation between Follow-up MRI Findings and Laboratory Results in Pyogenic Spondylodiscitis

2020 ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Imaging Method ◽  
Mri Findings ◽  
Pyogenic Spondylodiscitis ◽  
Tissue Responses ◽  
Laboratory Results ◽  
Tissue Changes ◽  
Soft Tissue Changes

Abstract Background: Although MRI is the gold-standard imaging method in the diagnosis of spondylodiscitis, role of follow-up imaging is debated and there can be discrepancies with regard to the significance of bony or soft tissue responses to treatment. Purpose of our study is to test whether the MRI changes on follow-up imaging correlate with laboratory findings of treatment response.Methods: A total of 48 patients with pyogenic spondylodiscitis who underwent baseline and follow-up MRI were retrospectively reviewed. The extent of bone marrow edema, paravertebral soft tissue inflammation, and disc height were compared on baseline and follow-up MRIs with the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels obtained from the medical records at baseline and on follow-up. Relationships between the MRI and laboratory changes were analyzed using the Spearmann correlation test.Results: The mean MRI follow-up period was 42.25 days. Based on the CRP (resolved: n=19, resolving: n=19, and aggravated: n=10), there was significant correlation between the laboratory results and the changes in the bone and soft tissues (p < 0.01, both). The correlation was best with soft tissue changes (rho: 0.48) followed by bony changes (rho: 0.41). Based on the ESR (resolved: n=8, resolving: n=22, and worsened: n=18), the correlation was stronger with bone changes (rho: 0.45, p < 0.01) than it was with soft tissue changes (rho: 0.39, p = 0.01).Conclusion: Follow-up MRI findings of pyogenic spondylodiscitis show variable tissue responses. CRP was best correlated with soft tissue changes, while ESR showed the best association with bony changes.

scholarly journals The Correlation between Follow-up MRI Findings and Laboratory Results in Pyogenic Spondylodiscitis

2020 ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Imaging Method ◽  
Mri Findings ◽  
Pyogenic Spondylodiscitis ◽  
Tissue Responses ◽  
Laboratory Results ◽  
Tissue Changes ◽  
Soft Tissue Changes

Abstract Background Although MRI is the gold-standard imaging method in the diagnosis of spondylodiscitis, role of follow-up imaging is debated and there can be discrepancies with regard to the significance of bony or soft tissue responses to treatment. Purpose of our study is to test whether the MRI changes on follow-up imaging correlate with laboratory findings of treatment response. Methods A total of 48 patients with pyogenic spondylodiscitis who underwent baseline and follow-up MRI were retrospectively reviewed. The extent of bone marrow edema, paravertebral soft tissue inflammation, and disc height were compared on baseline and follow-up MRIs with the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels obtained from the medical records at baseline and on follow-up. Relationships between the MRI and laboratory changes were analyzed using the Spearmann correlation test. Results The mean MRI follow-up period was 42.25 days. Based on the CRP (resolved: n=19, resolving: n=19, and aggravated: n=10), there was significant correlation between the laboratory results and the changes in the bone and soft tissues (p < 0.01, both). The correlation was best with soft tissue changes (rho: 0.48) followed by bony changes (rho: 0.41). Based on the ESR (resolved: n=8, resolving: n=22, and worsened: n=18), the correlation was stronger with bone changes (rho: 0.45, p < 0.01) than it was with soft tissue changes (rho: 0.39, p = 0.01). Conclusion Follow-up MRI findings of pyogenic spondylodiscitis show variable tissue responses. CRP was best correlated with soft tissue changes, while ESR showed the best association with bony changes.

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