scholarly journals Hidradenitis suppurativa, holistic approach and surgical reconstruction

2021 ◽  
Vol 6 (12) ◽  

We present a young adult male patient with chronic Hidradenitis Suppurativa (HS) stage Ⅱ-Ⅲ, mostly involving buttocks, thighs and perineum. The patient has been followed initially by a dermatologist for 2 years with trials of Biologic treatments. The ongoing purulent discharges made him quite dysfunctional. Patient was offered a definitive and extensive surgical option. Considering this conditions’ devastating social, psychological effects, such patients should be managed with a multidisciplinary team, elaborated education and counseling. Initial line of treatment plans should be considered as preparatory to the definitive surgical excisional therapy. Patient’s acceptance to the entire package that goes with the definitive surgery is fundamental for a successful and lasting outcome. Complete surgical resection of the disease and reconstruction remains to be the only available option for cure in a fully established HS.

2018 ◽  
Author(s):  
Sarah Humberg ◽  
Steffen Nestler ◽  
Mitja Back

Response Surface Analysis (RSA) enables researchers to test complex psychological effects, for example, whether the congruence of two psychological constructs is associated with higher values in an outcome variable. RSA is increasingly applied in the personality and social psychological literature, but the validity of published results has been challenged by some persistent oversimplifications and misconceptions. Here, we describe the mathematical fundamentals required to interpret RSA results, and we provide a checklist for correctly identifying congruence effects. We clarify two prominent fallacies by showing that the test of a single RSA parameter cannot indicate a congruence effect, and when there is a congruence effect, RSA cannot indicate whether a predictor mismatch in one direction (e.g., overestimation of one’s intelligence) is better or worse than a mismatch in the other direction (underestimation). We hope that this contribution will further enhance the validity and strength of empirical studies that apply this powerful approach.Humberg, S., Nestler, S., & Back, M. D. (2019). Response Surface Analysis in Personality and Social Psychology: Checklist and Clarifications for the Case of Congruence Hypotheses. Social Psychological and Personality Science, 10(3), 409–419. doi:10.1177/1948550618757600The journal version of this article can be found at: http://journals.sagepub.com/doi/full/10.1177/1948550618757600


1983 ◽  
Vol 4 (3) ◽  
pp. 243-259 ◽  
Author(s):  
Sigvard Rubenowitz ◽  
Flemming Norrgren ◽  
Arnold S. Tannenbaum

Gland Surgery ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1800-1805
Author(s):  
Ziyou Yu ◽  
Lingling Sheng ◽  
Weigang Cao ◽  
Shengli Li ◽  
Zhaohua Jiang

2018 ◽  
Vol 6 ◽  
pp. 2050313X1877872 ◽  
Author(s):  
Erika L Crowley ◽  
Ashley O’Toole ◽  
Melinda J Gooderham

Introduction: Hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome are chronic, debilitating diseases involving apocrine gland-bearing skin inflammation and bone inflammation, respectively. Although both often present with multiple comorbidities, single patient co-presentation is rare. Methods/Results: This study reports the 8-year treatment course of a 40-year-old man with hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome, and reviews relevant literature. Initial oral and topical antibiotics had little effect. Intralesional corticosteroid injections were effective for localized inflammatory lesions but insufficient for hidradenitis suppurativa control. Adalimumab initiation and local excision of a persistent HS lesion led to stabilization. Adalimumab provided dramatic back pain improvement. Synovitis, acne, pustulosis, hyperostosis, osteitis was diagnosed; adalimumab continuation with subsequent methotrexate addition resulted in hidradenitis suppurativa-synovitis, acne, pustulosis, hyperostosis, osteitis control. Conclusions: Literature regarding comorbid hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome therapy is scarce but growing. Adalimumab, methotrexate, intralesional corticosteroid, and lifestyle changes successfully maintained a severe hidradenitis suppurativa–synovitis, acne, pustulosis, hyperostosis, osteitis–syndrome case. Further studies beyond a case-based review could yield more definitive treatment plans.


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