Oral Cancer and Precancerous Lesions

Introduction: The burden of oral cancer is high in Hungary. Aim: To study the cost-effectiveness of potential oral cancer screening in Hungary. Method: Three strategies were compared: no introduction of screening, organized yearly screening for 40-year-old males in general medical practise, and opportunistic screening of high risk 40-year-old males in primary care. Local estimates of health utilities and costs of each health state and of the screening programmes were identified. The main outcomes were total costs, quality adjusted life years, and incremental cost-effectiveness ratios. Results: Depending on the efficacy of the treatments of precancerous lesions and the participation rate, screening strategies are cost-effective over a 15–20 year time course. The opportunistic screening of high risk people is more cost-effective than the other strategies. Conclusions: Opportunistic screening of high risk people would be cost-effective in Hungary. The uncertainty about the efficacy of the treatments of precancerous lesions requires more research to support evidence based health policy making. Orv. Hetil., 2016, 157(29), 1161–1170.

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Use of methylene blue as a diagnostic aid in early detection of oral cancer and precancerous lesions

British Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.bjoms.2006.08.017 ◽

2007 ◽

Vol 45 (7) ◽

pp. 590-591 ◽

Cited By ~ 31

Author(s):

Ya-Wei Chen ◽

Jiun-Sheng Lin ◽

Jenny Hwai-Jen Fong ◽

I-Kai Wang ◽

Shen-Ju Chou ◽

...

Keyword(s):

Methylene Blue ◽

Oral Cancer ◽

Early Detection ◽

Precancerous Lesions ◽

Diagnostic Aid

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Lycopene: features and potential significance in the oral cancer and precancerous lesions

Journal of Oral Pathology and Medicine ◽

10.1111/j.1600-0714.2010.00991.x ◽

2010 ◽

Vol 40 (5) ◽

pp. 361-368 ◽

Cited By ~ 32

Author(s):

Rui Lu ◽

Hongxia Dan ◽

Ruiqing Wu ◽

Wenxia Meng ◽

Na Liu ◽

...

Keyword(s):

Oral Cancer ◽

Precancerous Lesions ◽

Potential Significance

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Complete Blood Count as a Diagnostic Marker in Oral Lichen Planus

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl3.3510 ◽

2020 ◽

Vol 11 (SPL3) ◽

pp. 1766-1771

Author(s):

Indra G ◽

Maragathavalli G ◽

Deepika Rajendran

Keyword(s):

Oral Cancer ◽

Lichen Planus ◽

Oral Lichen Planus ◽

Blood Count ◽

Diagnostic Marker ◽

Complete Blood Count ◽

Precancerous Lesions ◽

Oral Submucous Fibrosis ◽

Oral Precancerous Lesions ◽

Oral Lichen

Oral precancerous lesions and conditions like oral lichen planus, leukoplakia, or oral submucous fibrosis have the potential to develop into oral cancer. Oral cancer accounts for approximately 3 % of all malignancies. Oral lichen planus is a premalignant condition occurring in the oral cavity due to various factors. Blood investigations are routinely done minimally invasive procedures carried out for various diagnostic purposes. The study aims to identify if the complete blood count (CBC) can be used as a pathologic diagnostic marker in an oral premalignant disorder like oral lichen planus. A total of 64 patients (38 female, 26 male) were taken into the study between the period July 2019 - March 2020. Each patient is exposed to blood investigations, and their results are studied. The results of the study show a minimal variation in the blood results. In conclusion, to determine if it can be used as a pathological diagnostic marker in premalignant disorders like oral lichen planus, further studies must be carried out in larger populations.

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An Update on Precancerous Lesions of Oral Cavity

International Journal of Medical and Dental Sciences ◽

10.18311/ijmds/2013/19825 ◽

2018 ◽

Vol 2 (1) ◽

pp. 70 ◽

Cited By ~ 2

Author(s):

Deepak Goyal ◽

Pardeep Goyal ◽

Harkanwal Preet Singh ◽

Chanchal Verma

Keyword(s):

Head And Neck Cancer ◽

Survival Rate ◽

High Risk ◽

Oral Cancer ◽

Malignant Transformation ◽

Death Rate ◽

Precancerous Lesions ◽

Correct Diagnosis ◽

Premalignant Lesions ◽

Timely Treatment

Oral cancer is the most common head and neck cancer, found in 270,000 patients annually worldwide. Some cancers develop from precancerous lesions; however, there is no definitive clinico pathological factor or biomarker that reliably enables malignant transformation to be predicted in an individual patient. Early detection and early treatment of oral cancer are important for improving the survival rate of patients; prevention of oral cancer will clearly contribute most to decreasing its death rate. So correct diagnosis and timely treatment of premalignant lesions with high risk of malignant transformation may help to prevent malignant transformation.

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Tobacco Cessation Programme for Cab Drivers in Mumbai, India and Assessment of Impact of Smoke Free Cabs on Cab Drivers and Commuters

Journal of Global Oncology ◽

10.1200/jgo.18.54000 ◽

2018 ◽

Vol 4 (Supplement 2) ◽

pp. 19s-19s

Author(s):

G.A. Mishra ◽

S. Pimple ◽

V. Kulkarni ◽

S. Gupta ◽

P. Majmudar

Keyword(s):

Cancer Screening ◽

Oral Cancer ◽

Tobacco Cessation ◽

Precancerous Lesions ◽

Tobacco Consumption ◽

Smoking Ban ◽

Attitudes And Practices ◽

Tobacco Epidemic ◽

Oral Cancer Screening ◽

Professional Assistance

Background: Tobacco epidemic is one of the biggest public health threats, killing nearly seven million people annually. With implementation of smoke free public places legislation, cabs in India are smoke free. However, large majority of the cab drivers are addicted to tobacco. Aim: The aims of the study were to measure cab driver's knowledge, about tobacco, understand pattern of tobacco usage, provide assistance in quitting tobacco, perform oral cancer screening, measure effectiveness of smoking ban in cabs and understand perceptions of cab drivers and commuters to ban. Methods: 400 cab drivers in Mumbai were enrolled after obtaining informed consent. Personal interviews were conducted to understand their knowledge, attitudes and practices regarding tobacco use, smoke free cab policies and their experiences and opinion regarding ban on smoking in cabs. They were offered health education, oral cancer screening and tobacco cessation assistance at regular intervals over a year. Results: 64% cab drivers used tobacco, mainly in smokeless forms (80%). 94% intended to quit, 64% had made previous quit attempts and 70% expressed need of assistance for quitting tobacco. 62% had displayed a No Smoking sign in their cab and 75% expressed full compliance by passengers to the ban. 112 cab drivers had oral precancerous lesions and one cab driver was diagnosed with invasive oral carcinoma. 49% cab drivers quit tobacco and 46% reduced their tobacco consumption by the end of ten months. Conclusion: Smoke free cab policy has increased awareness and reduced passive smoking and this may encourage tobacco users to quit the habit. However, many cab drivers are themselves addicted to tobacco and need professional assistance for quitting. Hence, tobacco cessation - assisting the current users to quit tobacco needs to go hand in hand with smoke free policies. Smoke free cab policies have received enormous support from the cab drivers in Mumbai. There was encouraging compliance to smoke free policies from the commuters. Tobacco quit rate of 49% was achieved by the end of the program.

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