scholarly journals Diagnostic Accuracy of Ultrasound Versus Computed Tomographic Guided Fine Needle Aspiration Cytology

1970 ◽  
Vol 1 (1) ◽  
pp. 9-14 ◽  
Author(s):  
SMK Nahar Begum ◽  
ARMS Ekram ◽  
D Uddin ◽  
QT Islam ◽  
J Bhaduri
Keyword(s):  
Diagnostic Accuracy ◽  
Economic Status ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Late Complications ◽  
Ct Guidance ◽  
Ct Guided ◽  
Computed Tomographic ◽  
Image Guided ◽  
The Poor

 Image guided FNAC of pulmonary lesions are widely applied now a days. Most of the lesions which are located nearer to the chest wall can be well visualized by ultrasonography. Whereas smaller lesions, deeply located ones, mediastinal or juxtra-hilar lesions may not be visualized sonographically. In those cases CT-guidance becomes beneficial. We report 127 FNACs done during a 2 year period. In considering the poor economic ability of the patient USG-guidance was preferred provided the lesion could be well visualized. Ultrasound guided method was successfully performed in majority of cases except a few where CT-guidance was necessary. After first aspiration an immediate cytological assessment was done by a quick staining method and in case of inadequacy of the specimen a second pass was made within an hour. Different pathological spectrum of diseases were diagnosed cytologically and was compared with their final diagnosis. Negligible immediate or late complications were noticed. Image guided FNAB of intra-thoracic masses can therefore be made with minimum complication, can allow the physician to decide the mode of treatment in a shortest possible time and in most of the cases an ultrasound guidance is sufficient enough considering the poor economic status of people in this subcontinent. Key Words : CT Guided FNAC; USG FNAC; Diagnostic Accuracy DOI: 10.3329/akmmcj.v1i1.7453 Anwer Khan Modern Medical College Journal 2010; 1(1): 09-14

scholarly journals Ultrasound and Computed Tomographic Guided Fine Needle Aspiration Cytology of Intrathoracic Lesions

1970 ◽  
Vol 20 (2) ◽  
pp. 110-115
Author(s):  
AMK Nahar Begum ◽  
ARMS Ekram ◽  
D Uddin ◽  
QT Islam ◽  
MM Alam ◽  
...  
Keyword(s):  
Economic Status ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Late Complications ◽  
Ct Guidance ◽  
Aspiration Cytology ◽  
Computed Tomographic ◽  
Image Guided ◽  
The Poor ◽  
Needle Aspiration Cytology

Image guided FNAB of pulmonary lesions are widely applied now a days. Most of the lesions which are located nearer to the chest wall can be well visualized by ultrasonography. Whereas smaller lesions, deeply located ones, mediastinal or juxtra-hilar lesions may not be visualized sonographically. In those cases CT-guidance becomes beneficial. We report 127 FNABs done during a 2 year period. In considering the poor economic ability of the patient USG-guidance was preferred provided the lesion could be well visualized. Ultrasound guided method was successfully performed in majority of cases except a few where CT-guidance was necessary. After first aspiration an immediate cytological assessment was done by a quick staining method and in case of inadequacy of the specimen a second pass was made within an hour. Different pathological spectrum of diseases was diagnosed cytologically and was compared with their final diagnosis. Negligible immediate or late complications were noticed. Image guided FNAB of intra-thoracic masses can therefore be made with minimum complication, can allow the physician to decide the mode of treatment in a shortest possible time and in most of the cases an ultrasound guidance is sufficient enough to meet the poor economic status of people in this subcontinent. doi: 10.3329/taj.v20i2.3070 TAJ 2007; 20(2): 110-115

Accuracy of CT-guided transthoracic needle biopsy of lung lesions: Results of 612 consecutive procedures

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 18022-18022
Author(s):  
U. Ricardi ◽  
A. M. Priola ◽  
S. M. Priola ◽  
S. Novello ◽  
A. Cataldi ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Needle Biopsy ◽  
Inflammatory Cells ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Lesion Size ◽  
Maximum Diameter ◽  
Transthoracic Needle Biopsy ◽  
Ct Guided ◽  
Lung Lesions

18022 Background: CT-guided transthoracic needle biopsy (TNB) is commonly used in diagnostic work-up of lung lesions. The availability of a on-site pathologist at the time of the procedure ameliorate its sensitivity, reduce the number of biopsies and false negatives. Methods: 612 procedures (608 patients with a CT-documented central or peripheral pulmonary lesion) performed at S. Luigi Hospital between November 2002 and August 2005 were prospectively analyzed; 66% males, median age was 66 years (range 29–87). Ineligibility criteria for the procedure included severe coagulopathy, previous contralateral pneumonectomy, lesions with a maximum diameter less than 5 mm or the impossibility to understand the procedure or to maintain the clinostatism for the time of the procedure. The on-site pathologist assigned to each specimen a semiquantitative score: 0 for bloody sample without other cells, 1 for aspecific benign or inflammatory cells, 2 for malignant cells without histotype characterization and 3 for well established benign or malignant histotype. Results: Most of the procedures was performed by fine needle aspiration biopsy, while in a minority of cases a tru-cut biopsy was requested. In 57.2% of the cases a single transthoracic access (range 1–4) was used and in 31% the procedure was repeated on the basis of the radiologist/pathologist judgment. In 154 patients a surgical resection was subsequently performed, while 454 were patients non-surgical. A score of 3 was obtained in 71% of cases (88% malignancies), 2 in 12.5%, 1 in 7.5% and 0 in 9%. A definitive diagnosis was made in 83.5% of procedures, while a score of 0–1 was assigned in 101 cases. Among 458 malignancies there were 411 lung cancer, 7 non-epithelial cancers and 40 metastases with only 1 false positive. The diagnostic accuracy for benign and malignant lesions was 67% and 92%, respectively (Pearson’s test p<0.005) with overall diagnostic accuracy of 83.3%. The variables affecting diagnostic accuracy were final diagnosis (benign 67%, malignant 92%, p<0.001) and lesion size (lesion 5 cm 78%, p<0.05). The presence of cavitation or necrotic areas and location of the lesion didn’t affect the diagnostic accuracy. Conclusion: In consecutive cases of CT-guided TNB final diagnosis and lesion size affect diagnostic accuracy. No significant financial relationships to disclose.

scholarly journals Efficacy of rapid on-site cytological evaluation (ROSE) by a pulmonologist in determining specimen adequacy and diagnostic accuracy in interventional diagnosis of lung lesions

2021 ◽  
Vol 49 (2) ◽  
pp. 030006052098268
Author(s):  
Mingli Yuan ◽  
Yafei Wang ◽  
Wen Yin ◽  
Yang Xiao ◽  
Manman Hu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Diagnostic Accuracy ◽  
Cell Carcinoma ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Small Cell ◽  
Diagnostic Efficacy ◽  
Lung Lesions ◽  
Fine Needle ◽  
Cytological Evaluation

Objective To evaluate the efficacy of rapid on-site cytological evaluation (ROSE) in determining specimen adequacy and diagnostic accuracy in the interventional diagnosis of lung lesions. Methods This retrospective study included 127 consecutive cases of lung lesions, which were sampled by bronchoscopy or transthoracic fine needle aspiration, and diagnosed on ROSE followed by histopathology. ROSE was performed by a trained pulmonologist and the diagnosis of ROSE was compared with the final diagnosis. Results The sensitivity of ROSE in determining adequacy of specimens was 97.5% and specificity in determining inadequacy was 85.7%. The diagnostic efficacy of ROSE for assessing malignancy (sensitivity of 94.5% and specificity of 100%) and non-malignancy (sensitivity of 97.8% and specificity of 100%) was excellent. The sensitivity of ROSE for diagnosing small cell carcinoma (100%) was highest, followed by adenocarcinoma (89.2%) and squamous cell carcinoma (75.0%). Performance of ROSE by a trained pulmonologist also determined tuberculosis with a high diagnostic sensitivity (83.3%) and specificity (100%). Conclusions A trained pulmonologist can reliably carry out ROSE to ensure the adequacy of the sample, distinguish between malignancy and non-malignancy, and make a preliminary diagnosis in a large number of cases.

CT-guided transthoracic fine-needle aspiration versus transbronchial fluoroscopy-guided needle aspiration in pulmonary nodules

1998 ◽  
Vol 39 (4) ◽  
pp. 395-399 ◽  
Author(s):  
S. Shankar ◽  
Madhu Gulati ◽  
D. Gupta ◽  
A. Rajwanshi ◽  
S. Suri
Keyword(s):  
Fine Needle Aspiration ◽  
Diagnostic Yield ◽  
Pulmonary Nodules ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Definitive Diagnosis ◽  
Ct Guided ◽  
Fine Needle ◽  
Group A ◽  
Made In

Purpose: To evaluate the diagnostic yield of CT-guided (CTNAB) and fluoroscopy-guided transbronchial (TBNA) fine-needle aspiration cytology in pulmonary nodules and to compare their complications. Material and Methods: Thirty patients with pulmonary nodules not abutting upon the chest wall and inaccessible to bronchoscopy were randomised for CTNAB or TBNA. Eighteen patients underwent CTNAB and 16 TBNA. Four patients underwent both procedures. Results: In the CTNAB group, a definitive diagnosis could be made in 14 (78%) out of 18 patients whereas in the TBNA group, a definitive diagnosis was made in 11 (69%) out of 16 patients. This difference was not statistically significant ( p>0.05). The final diagnosis in 29 out of 30 patients comprised primary bronchogenic carcinoma in 14 patients, metastases in 5 patients, and benign lesions in 10 patients (34%) of which 3 lesions (30%) were of tuberculous aetiology. There were 2 asymptomatic pneumothoraces in the CTNAB group and no complication was observed in the TBNA group. Conclusion: Both techniques were safe and effective in the diagnosis of peripheral pulmonary lesions. TBNA was best suited for lesions larger than 3 cm and located in the middle and lower lobes while CTNAB could be used for any lesions.

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