scholarly journals An Approach to Soft Tissue Mass In The Gall Bladder

2019 ◽  
Vol 7 (1) ◽  
pp. 29-34
Author(s):  
Hasina Alam ◽  
Tanvir Ahmed ◽  
Hashim Rabbi ◽  
Md Mamunur Rashid ◽  
Mohammad Ali
Keyword(s):  
Soft Tissue ◽  
Gall Bladder ◽  
Ct Scan ◽  
Soft Tissue Mass ◽  
Curative Surgery ◽  
Tissue Mass ◽  
Stage Ib ◽  
External Biliary Drainage ◽  
Mass Lesions

Background: Soft tissue mass in gall bladder (GB) is a radiologic finding commonly encountered in surgical practice. It needs proper evaluation as there is a fair chance that it can be a malignant lesion. Gall bladder cancer (GBC) is considered an incurable disease with an extremely poor prognosis. However, there is good chance of survival if it can be diagnosed in earlier stages (stage Ib, II, selective III). Methods: All consecutive cases of soft tissue mass lesions of GB found in ultrasonogram of abdomen and admitted in Hepato-Biliary-Pancreatic Surgery (HBPS) unit of BIRDEM hospital, from January 2009- September 2016, were included in this study. Detailed history and thorough clinical examination was done in all cases. Pre-operative evaluations were done by ultrasound, Tumor marker (CA19.9) & CT scan,. CT scan was a crucial investigation for all the patients, as depending on the findings, decision was made whether a patient is eligible for a possible curative surgery or not. On-table frozen section biopsy or imprint cytology was done for tissue diagnosis. Radical resection was done for the histology/ cytology proved malignancy of gallbladder (stage Ib, II, selective III). Post-cholecystectomy patients also underwent full thickness excision of the umbilical port. In benign cases only cholecystectomy was done. Advanced GBC cases underwent FNAC for tissue diagnosis followed by palliative chemotherapy. Some needed endoscopic or surgical palliation in the form of percutaneous external biliary drainage, endobiliary prosthesis, triple bypass, hepaticojejunostomy, left duct anastomosis, gastrojejunostomy, ileotransverse anastomosis, external biliary drainage etc before chemotherapy. All the GBC patients were regularly followed according to a schedule. Results: We are reporting 334 cases of soft tissue mass lesions of GB. Female 191 (57.2%) and male 143 (42.81%), M : F = 1 : 1.3 ,,between the ages of 32 and 88 years. Of these, 81 patients (24.2%) turned out to be benign; another 81 patients (24.2%) were in early stage (Ib, II selective III). The rest of 172 patients (51.5%) showed signs of advanced malignancy in USG & CT scan. Post-operative complications occurred in 27 cases (8.1%). During follow-up, 34 patients (42%) have crossed their 5 years of disease free survival after curative surgery. Rest of the patients (44 cases), after curative surgery, are still under follow-up. The 172 patients in Stage III & IV disease who underwent some sort of palliative procedure, had a mean survival of 7.2 months. Conclusion: Soft tissue mass in gall bladder picked up by imaging has a very high chance to be malignant. Among these malignant patients, a good number has a chance of curative resection if evaluated and managed properly. Bangladesh Crit Care J March 2019; 7(1): 29-34

scholarly journals Nasal Cavity Ossifying Fibrosarcoma: An Unusual Fibro-Osseous Neoplasm

2010 ◽  
Vol 89 (11) ◽  
pp. E1-E3 ◽  
Author(s):  
Yadiel A. Alameda ◽  
Carlos Perez-Mitchell ◽  
José M. Busquets
Keyword(s):  
Soft Tissue ◽  
Nasal Cavity ◽  
English Language ◽  
Clinical Presentation ◽  
Soft Tissue Mass ◽  
Histopathologic Examination ◽  
Left Nasal Cavity ◽  
Tissue Mass ◽  
Language Literature

We describe the case of a 65-year-old woman who presented with left nasal obstruction. Clinical and radiographic examinations revealed the presence of a soft-tissue mass that had obliterated the left nasal cavity. The mass was completely excised via an endoscopic approach. Histopathologic examination identified the tumor as an ossifying fibrosarcoma. The patient recovered uneventfully and remained free of disease at the 2-year postoperative follow-up. To the best of our knowledge, no case of an ossifying fibrosarcoma of the nasal cavity has been previously reported in the English-language literature. We discuss the features of this case and the clinical presentation, diagnosis, and management of fibrosarcomas of the nasal cavity and paranasal sinuses.

scholarly journals Novel RGAG1-BCOR gene fusion revealed in a somatic soft tissue sarcoma with a long follow-up

2021 ◽  
Author(s):  
Mauro Vasella ◽  
Ulrich Wagner ◽  
Christine Fritz ◽  
Kati Seidl ◽  
Luca Giudici ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Gene Fusion ◽  
Soft Tissue Mass ◽  
Soft Tissue Tumors ◽  
Rt Pcr ◽  
Tissue Mass ◽  
Myxoid Chondrosarcoma ◽  
Next Generation Sequencing Ngs ◽  
Generation Sequencing

AbstractBCOR-rearranged sarcomas are rare and belong to the Ewing-like sarcomas (ELS). Their morphology and histopathological features make the diagnosis challenging. We present a case, initially diagnosed as an unusual extraskeletal myxoid chondrosarcoma (EMC). A 54-year-old male patient developed an asymptomatic swelling of the lower leg. Imaging showed a 9.5-cm large intramuscular soft tissue mass. Due to its morphological and immunohistochemical profile on biopsy, it was initially diagnosed as an EMC. The patient was treated by complete resection and adjuvant radiotherapy and remained free of tumor at 7 years follow-up. Using next-generation sequencing (NGS), we retrospectively identified RGAG1-BCOR gene fusion (confirmed by RT-PCR), which has not been described in somatic soft tissue tumors so far. This finding broadens the spectrum of partner genes in the BCOR-rearranged sarcomas in a tumor with a well-documented, long clinical follow-up.

scholarly journals Primary sternal osteomyelitis mimicking a neoplastic growth

2017 ◽  
Vol 5 (8) ◽  
pp. 3726
Author(s):  
Nagadarshini Ramagiri Vinod ◽  
Hassan Tahir ◽  
Arslan Ahmed
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Ct Scan ◽  
Soft Tissue Tumor ◽  
Chronic Osteomyelitis ◽  
Soft Tissue Mass ◽  
Tissue Growth ◽  
Tissue Mass ◽  
Neoplastic Growth ◽  
Sternal Osteomyelitis

Chronic osteomyelitis usually present as bony growth but it can rarely present as a soft tissue growth mimicking neoplasm and is usually diagnosed by the combination of radiology and microbiology. This is a case report of an adult male who had chronic osteomyelitis mimicking a neoplastic growth of soft tissue. CT scan showed soft tissue mass mimicking a soft tissue tumor but microbiology test and MRI confirmed the diagnosis of chronic osteomyelitis.

Gastric smooth muscle hamartoma in a cat

2010 ◽  
Vol 12 (4) ◽  
pp. 334-337 ◽  
Author(s):  
Thomas J. Smith ◽  
Wendy I. Baltzer ◽  
Craig G. Ruaux ◽  
Jerry R. Heidel ◽  
Patrick Carney
Keyword(s):  
Smooth Muscle ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Clinical Signs ◽  
Surgical Excision ◽  
Endoscopic Examination ◽  
Tissue Mass ◽  
Gastric Smooth Muscle ◽  
Esophageal Sphincter

An 11-year-old cat presented for evaluation of intermittent vomiting, constipation and hyporexia of 3 weeks duration. Ultrasonographic and endoscopic examination revealed a soft tissue mass adjacent to the lower gastro-esophageal sphincter. Surgical excision of the mass was successfully performed resulting in a resolution of clinical signs. Histologically the mass was consistent with a smooth muscle hamartoma. At follow-up 7 months after surgery, the cat remained free from clinical signs.

scholarly journals Isolated Incudostapedial Cholesteatomas: Unique Radiologic and Surgical Features

2020 ◽  
pp. 014556132097378
Author(s):  
Bridget MacDonald ◽  
Krishna Bommakanti ◽  
Moises Mallo ◽  
Daniela Carvalho
Keyword(s):  
Hearing Loss ◽  
Soft Tissue ◽  
Ct Scan ◽  
Middle Ear ◽  
Conductive Hearing Loss ◽  
Soft Tissue Mass ◽  
Ossicular Chain ◽  
Ct Scans ◽  
Tissue Mass ◽  
Conductive Hearing

Objectives: Congenital cholesteatomas originate from epithelial tissue present within the middle ear in patients with an intact tympanic membrane, no history of otologic surgery, otorrhea, or tympanic membrane perforation. They are diagnosed by a pearl-like lesion on otoscopy and computed tomography (CT) scan showing an expansile soft-tissue mass. We describe a series of patients with no prior otologic history presenting with progressive unilateral conductive hearing loss and normal otoscopy. The CT scans showed ossicular erosion without obvious soft-tissue mass. Surgery confirmed incudostapedial erosion found to be cholesteatoma. In this study, we characterize the clinical course of patients diagnosed with isolated incudostapedial cholesteatoma (IIC) and review possible pathologic mechanisms. Methods: Retrospective review of IIC cases treated by the Department of Pediatric Otolaryngology, Rady Children’s Hospital, San Diego, 2014 to 2020. Data included patient demographics, clinical features, imaging, surgical findings, and audiologic data. Results: Five patients were diagnosed with IIC (3 [60%] female; mean age at presentation 10.7 years [range 5.5-16.0]). All patients presented with postlingual unilateral conductive hearing loss and normal otoscopy without any past otologic history; delay in diagnosis ranged from 4 months to several years. The CT scans showed ossicular chain erosion with an absent long process of the incus and/or stapes superstructure. All patients underwent middle ear exploration, revealing a thin layer of cholesteatoma in the incudostapedial region, confirmed by histopathology. Mean preoperative speech reception threshold was 55 dB and improved to a mean of 31 dB in the 4 patients who underwent ossicular chain reconstruction. Conclusion: Isolated incudostapedial cholesteatoma should be included as a possible etiology in pediatric patients with insidious onset of unilateral conductive hearing loss with normal otoscopy, unremarkable otologic history, and a CT scan showing ossicular abnormality/disruption without notable middle ear mass. These patients should be counseled preoperatively regarding the possibility of cholesteatoma and should undergo middle ear exploration with possible ossiculoplasty.

scholarly journals Retroperitoneal Leiomyoma

2019 ◽  
Vol 20 (1) ◽  
pp. 26-28
Author(s):  
Abu Taher Md Ashaduzzaman ◽  
Abm Jamal ◽  
Md Aminul Islam Khan ◽  
Haridas Saha
Keyword(s):  
Soft Tissue ◽  
Ct Scan ◽  
Soft Tissue Mass ◽  
Surgical Removal ◽  
Rare Entity ◽  
Tissue Mass ◽  
Benign Condition ◽  
Histopathological Findings ◽  
Rare Neoplasm

Leiomyoma is a common benign condition for which many hysterectomies are performed everyyear. Leiomyomas found retroperitoneally are a rare entity, especially primary. We report herea case of 44-year-old, para 5+0 who presented with mass in the abdomen and lower abdominalpain. CT- scan shows a huge retroperitoneal soft tissue mass. The mass was removedcompletely. Histopathological findings were consistent with leiomyoma. Retroperitonealleiomyoma is a rare neoplasm and treatment is surgical removal. Journal of Surgical Sciences (2016) Vol. 20 (1) : 26-28

scholarly journals NK/T Cell Lymphoma, Nasal Type: a Case Report

2018 ◽  
Vol 3 (2) ◽  
Keyword(s):  
T Cell ◽  
Soft Tissue ◽  
Ct Scan ◽  
Progressive Disease ◽  
Cell Lymphoma ◽  
Soft Tissue Mass ◽  
T Cell Lymphoma ◽  
Tissue Mass ◽  
Nasal Type ◽  
Nk T Cell

Extranodal NK/T cell lymphoma, nasal type is a rare, clinically aggressive, locally destructive and necrotizing disease. It represents 7-10% of all non-Hodgkin lymphomas with a 1-year survival rate of 40%. This case will be the first reported case in the Philippines. We report 44 year old Filipino male who presented with one year history of foul smelling left nasal discharge. Physical examination was unremarkable except for ~1 x 1 cm cavity at the soft palate. Several consult done, given nasal drops and antibiotics with no relief of symptoms. Nasopharyngeal CT scan revealed a 5.2 x 3.1 cm soft tissue mass at left nasal cavity extending into the contralateral nasal cavity, no intracranial extension. After three unremarkable nasal biopsies, histopathology revealed round cell neoplasm, with immunohistochemical stains consistent with NK/T cell lymphoma Nasal type localized disease. Metastatic work up were all unremarkable. He then underwent concurrent chemotherapy with Cisplatin and radiotherapy (30cGY). The palatal cavity increased in size to 3 x 3 cm after completion of radiotherapy, however the soft tissue mass decreased in size hence three cycles of VIPD (etoposide, ifosfamide, cisplatin, dexamethasone) was given. Patient remained asymptomatic, with a good performance score. Nasal endoscopy and nasopharyngeal MRI done post-treatment showed no evidence of lesion with stable palatal cavity defect. CT scan of chest however revealed a left upper lobe non-calcified 2cm nodule with bilateral subpleural nodules. In a rare yet aggressive malignancy such as NK/T cell lymphoma wherein the primary lesion had good response to treatment, a new lung lesion could impose progressive disease such as metastasis. We could either treat patient as a case of progressive disease and subject him to a battery of chemotherapy or we could biopsy the new lesion. Either way, delay in diagnosis cause undue anxiety and uncanny cost to patient. In our case, biopsy was done and indeed it was of infectious in origin. The malignancy responded well to treatment.

Fibro-Osseous Pseudotumor of the Hand

2016 ◽  
Vol 21 (02) ◽  
pp. 269-272 ◽  
Author(s):  
Vasileios A. Kontogeorgakos ◽  
Dionysios J. Papachristou ◽  
Sokratis Varitimidis
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Dorsal Surface ◽  
Tissue Mass ◽  
Peripheral Ring ◽  
High Grade Sarcoma ◽  
Soft Tissue Masses ◽  
Web Space ◽  
Ring Core

Fibro-osseous pseudotumor of digits (FOPD) is an uncommon histological diagnosis. Clinical and imaging findings may resemble high-grade sarcoma or infection. We describe a patient with progressive pain and swelling at the dorsal surface of the first web space. MRI and CT imaging revealed an intramuscular heterogenous soft tissue mass defined by a mineralized peripheral ring. Core needle biopsy diagnosed FOPD. Eight months later a matured ossified nodule that was quite smaller than the initial soft tissue mass was excised. The patient is symptom free without local recurrence at 1 year follow up. Soft tissue masses of the hand pose a challenging diagnostic and therapeutic issue. An in depth interpretation of clinical, imaging and histology findings is important to avoid erroneous diagnosis and treatment.

scholarly journals Giant Intramuscular Lipoma Otot Biceps Brachii

2017 ◽  
Vol 2 (2) ◽  
pp. 79-83
Author(s):  
Eristan N. Napitupulu ◽  
Bambang Supriyadi ◽  
Yana Supriatna
Keyword(s):  
Soft Tissue ◽  
Ct Scan ◽  
Signal Intensity ◽  
Biceps Brachii ◽  
Soft Tissue Mass ◽  
Biceps Brachii Muscle ◽  
Tissue Mass ◽  
Primary Tumors ◽  
Intramuscular Lipoma ◽  
Giant Lipoma

Intramuscular lipoma is a relatively uncommon condition and accounts for just 1,8% of all primary tumors of adipose tissue and less than 1% of all lipoma. This tumor arises within skeletal muscle fibers at various locations. However, giant intramuscular lipomas of biceps brachii muscle are rare tumors. A 48-years old man presented with a mass on his right upper-arm. The mass existed for one year and has since increased in size. On physical examination, the mass was pain upon palpation and completely mobile. Plain radiography, the soft tissue mass unremarkable. Computed tomography (CT) scan revealed a hypodense mass situated within right biceps brachii muscle with -72 until -83 Hounsfield. Magnetic resonance imaging (MRI), the mass was found inside of biceps brachii muscle. In T1- and T2- weighted images, the lesion area demonstrated high signal intensity, and SPAIR showed signal suppression similar to normal fat. The patient underwent radical excision of the lesion, which was found to be greater than 12 cm in size. Final pathology revealed intramuscular lipoma. A lipoma of greater than 5 cm is classified as a giant lipoma. Giant lipoma in the upper extremities and involving biceps brachii muscle are rare. The plain radiographs may either be unremarkable or may demonstrate a radiolucent soft tissue mass of fat opacity. On CT and MRI, the lipoma appears as an non-invasive mass with homogenous fat signal intensity. The main differential diagnosis of intramuscular lipomas is well-differentiated liposarcomas. The proper management is open excision. The pathological report is vital to confirm the diagnosis. We reported a rare case of giant intramuscular lipoma of biceps brachii who was successfully opened excision at our institute. CT scan and MRI can identify and localize these tumours, and facilitate the operative planning

Duodenogastric Intussusception with Concurrent Gastric Foreign Body in a Dog: A Case Report and Literature Review

2013 ◽  
Vol 49 (1) ◽  
pp. 64-69 ◽  
Author(s):  
David A. Allman ◽  
Michael P. Pastori
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Foreign Body ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Foreign Object ◽  
Endoscopic Removal ◽  
Tissue Mass ◽  
Abdominal Radiographs

A 3 yr old spayed female boxer weighing 22.8 kg was presented for severe, acute vomiting and tenesmus. Tachycardia, tachypnea, dehydration, and abdominal pain were present on physical examination. Abdominal radiographs showed a foreign object (golf ball) in the fundus of the stomach, and a larger, round, soft-tissue opacity mass in the region of the pylorus. Endoscopic removal of the foreign object was unsuccessful. A large soft-tissue mass (duodenogastric intussusception) was visualized with endoscopy, but was not correctly diagnosed until surgery. A midline exploratory celiotomy was performed and the duodenogastric intussusception was diagnosed and manually reduced. Severe pyloric wall edema and minimal bruising were present. A routine fundic gastrotomy was performed and the foreign object was removed. A right-sided incisional gastropexy and duodenopexy were performed in attempt to prevent recurrence of the intussusception. The dog was discharged from the hospital 38 hrs after surgery, and was normal on follow-up 1 yr after surgery. The dog in this report is the sixth documented case of duodenogastric/pylorogastric intussusception in the veterinary literature. This is the first reported case with a concurrent gastric foreign body and endoscopic visualization of the intussusception.

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