scholarly journals Helicobacter Pylori is associated with decrease serum level of the thyroid hormonal in healthy elderly population

2017 ◽  
Vol 16 (4) ◽  
pp. 515-520
Author(s):  
Sri Suwarni ◽  
Cilmiaty Risya ◽  
Dono Indarto ◽  
Suradi Pulmonology

Background: Helicobacter pylori infection is the most prevalence infectious disease as it affects more than half of the world population and causes chronic cellular inflammatory response in the gastric mucosa. Helicobacter pylori infection has been epidemiologically proven to be linked to extra-digestive conditions and disease. It has been speculated that H.pylori infection may be responsible for various endocrine disorders. The thyroid may be one of the targets of Helicobacter pylori chronic inflammation. Here we sought too investigate whether H.pylori infections were associated with decrease level of the thyroid hormonal.Methods: This study involved elderly aged 50-90 years who had visited a health promotion center for elderly. A total 101 euthyroid subjects were been enrolled in this cross-sectional study. Diagnosed of Helicobacter.pylori infections by ELISA of Ig G antibodies of Helicobacter pylori. We examine serum T3 level and serum TSH level by ELEXIS. For statistical method we use Pearson bivariat analysis to determine the association of two variable,and linier regression to determine which variable is more influented by Helicobacter pylori.Results: Fourty-two (41,6 %) subjects had been diagnosed with H.pylori infections. Pearson bivariat analysis showed that Helicobacter pylori infection was significantly associated with decreased serum T3 level ( correlations coefficient r = -0,66 ,p< 0,001 ). The prevalence of Helicobacter pylori infection showed a increasing trend as serum TSH level decreased (correlations coefficient r = -0,53, p < 0,001). Linier regression analysis showed thatHelicobacter pylori infection was significantly associated with the risk of decreased thyroid hormonal fuction ( B = -0,272. R2 = 0,676. P < 0.001 ).Conclusion: Our results suggested that H.pylori infections were significantly associated with the decreased serum level of T3 and TSH serum level in the healthy elderly population, whose thyroid functions were in the reference range.Bangladesh Journal of Medical Science Vol.16(4) 2017 p.515-520

2014 ◽  
Vol 29 ◽  
pp. 25-28 ◽  
Author(s):  
Tadashi Shimoyama ◽  
Daisuke Chinda ◽  
Masashi Matsuzaka ◽  
Ippei Takahashi ◽  
Shigeyuki Nakaji ◽  
...  

2016 ◽  
Vol 11 (4) ◽  
Author(s):  
Zardis Rezaeimehr ◽  
Seyed Reza Hosseini ◽  
Zeinab Darbandi ◽  
Seyed Amirhossein Hosseini ◽  
Farzan Kheirkhah ◽  
...  

2009 ◽  
Vol 15 (22) ◽  
pp. 2701 ◽  
Author(s):  
Konstantinos X Papamichael ◽  
Garyphallia Papaioannou ◽  
Helen Karga ◽  
Anastasios Roussos ◽  
Gerassimos J Mantzaris

2002 ◽  
Vol 97 (11) ◽  
pp. 2927-2928 ◽  
Author(s):  
Nagisa Yoshino ◽  
Kyoichi Adachi ◽  
Toshiharu Takashima ◽  
Youichi Miyaoka ◽  
Takafumi Yuki ◽  
...  

2020 ◽  
Vol 55 (6) ◽  
pp. 640-645
Author(s):  
Lei Feng ◽  
Rong Jian ◽  
Yan Wang ◽  
Yong Yao ◽  
Mingsheng Gao ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
pp. e11-e11
Author(s):  
Banafsheh Yalameha ◽  
Parto Nasri

One of the problems of renal disease patients, especially patients undergoing dialysis, is gastrointestinal complications caused by Helicobacter pylori infection. H. pylori has still high prevalence in most populations. It is estimated that about half of the world population is infected with this infection and it can change levels of most micronutrients such as magnesium. Different studies demonstrate that H. pylori may affect the metabolism of magnesium in renal failure. The present paper investigated the association of serum magnesium level with H. pylori infection. Nevertheless, it should be more evaluated by researchers and still many studies are necessary to confirm this issue.


2013 ◽  
Vol 2 (1) ◽  
pp. 28-33
Author(s):  
Rezina Karim ◽  
SM Moslehuddin Ahmed ◽  
Fahmida Begum

Helicobacter pylori infection is one of the most common infections in humans, with an estimated 50% of the world population being infected.  The infection is strongly associated with chronic gastritis, peptic ulcer, adenocarcinoma and non-Hodgkin’s lymphoma of stomach. The prevalence of infection is high in developing countries, demanding a reliable diagnostic and treatment method. The present study was designed to investigate the monoclonal antibody-based H. Pylori stool antigen test to screen H. pylori infection and assess efficacy of treatment in patients with peptic ulcer. A total of 89 patients who underwent upper gastrointestinal endoscopy from July 2007 to June 2008 at Bangabandhu Sheikh Mujib Medical University Hospital, Dhaka, Bangladesh were included in the study. Endoscopic findings showed that out of 89 patients, 54 (60.7%) had duodenal ulcers, 24 (27%) had antral erosion and 5 (5.6%) had gastric ulcers. With RUT (rapid urease test) and histopathology of biopsy samples of 89 patients, 78 (87.6%) patients were found to be H. pylori positive. Stool antigen test was positive in 72 (92.3%) out of 78 H. pylori positive patients. The monoclonal stool antigen test (SAT) revealed 92.3% sensitivity and specificity of 100% before treatment. Among 52 follow-up patients (after treatment), 5 (9.6%) patients were detected positive by histology, RUT and stool antigen test, and 35 (67.3%) patients were negative by 3 tests. So the monoclonal SAT revealed 100% sensitivity and 100% specificity after treatment. The monoclonal stool antigen test is highly sensitive and a specific tool for diagnosis of H. pylori infection before therapy and can assess the success of eradication after therapy. It also offers the advantage of specificity and reliability over the invasive test.  It is easy and quick to use, non-invasive and does not require any special technology.South East Asia J Public Health | Jan-June 2012 | Vol 2 Issue 1 | 28-33 DOI: http://dx.doi.org/10.3329/seajph.v2i1.15262


Author(s):  
Aparna Patange ◽  
Harsh Shah ◽  
Harshil Vora

Background: Hypertension may be the initial clinical presentation for at least 15 endocrine disorders, including overt and subclinical hyperthyroidism and hypothyroidism. The correction of thyroid dysfunction may normalize Blood Pressure (BP) in most cases, therefore checking thyroid function is essential during the workup for hypertension. The present study was conducted to find out the association between hypertension and thyroid dysfunction.Methods: It was a retrospective, observational study conducted among patients having hypertension visiting the outpatient department of Medicine in KIMS Karad, during the period of 2 months.Results: The mean values of various thyroid function parameters among hypertensive cases was assessed in the current study, Authors found that the mean Serum T3 level was 93.5917±32.82, Mean Serum T4 level was 6.72±1.64 and the mean Serum TSH level was 2.52±2.71. Among all the cases about 52% cases had deranged thyroid function reports.Conclusions: The results of this study suggest an association between subclinical hypothyroidism and increased blood pressure levels.


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