scholarly journals Helicobacter pylori infection and serum magnesium in kidney disease; current concepts

2019 ◽  
Vol 9 (1) ◽  
pp. e11-e11
Author(s):  
Banafsheh Yalameha ◽  
Parto Nasri
Keyword(s):  
Helicobacter Pylori ◽  
Serum Magnesium ◽  
Magnesium Level ◽  
Helicobacter Pylori Infection ◽  
World Population ◽  
Serum Magnesium Level ◽  
Gastrointestinal Complications ◽  
High Prevalence ◽  
The World ◽  
H Pylori

One of the problems of renal disease patients, especially patients undergoing dialysis, is gastrointestinal complications caused by Helicobacter pylori infection. H. pylori has still high prevalence in most populations. It is estimated that about half of the world population is infected with this infection and it can change levels of most micronutrients such as magnesium. Different studies demonstrate that H. pylori may affect the metabolism of magnesium in renal failure. The present paper investigated the association of serum magnesium level with H. pylori infection. Nevertheless, it should be more evaluated by researchers and still many studies are necessary to confirm this issue.

scholarly journals RESISTANCE TO AMOXICILLIN, CLARITHROMYCIN AND CIPROFLOXACIN OF Helicobacter pylori ISOLATED FROM SOUTHERN BRAZIL PATIENTS

2014 ◽  
Vol 56 (3) ◽  
pp. 197-200 ◽  
Author(s):  
Simone Ulrich Picoli ◽  
Luiz Edmundo Mazzoleni ◽  
Heriberto Fernández ◽  
Laura Renata De Bona ◽  
Erli Neuhauss ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Eradication Therapy ◽  
Empirical Therapy ◽  
British Society ◽  
World Population ◽  
Southern Brazil ◽  
First Line ◽  
The World ◽  
Antibiotics Susceptibility ◽  
H Pylori

Introduction: Helicobacter pylori is a bacteria which infects half the world population and is an important cause of gastric cancer. The eradication therapy is not always effective because resistance to antimicrobials may occur. The aim of this study was to determine the susceptibility profile of H. pylori to amoxicillin, clarithromycin and ciprofloxacin in the population of Southern Brazil. Material and methods: Fifty four samples of H. pylori were evaluated. The antibiotics susceptibility was determined according to the guidelines of the British Society for Antimicrobial Chemotherapy and the Comité de l'Antibiogramme de la Société Française de Microbiologie. Results: Six (11.1%) H. pylori isolates were resistant to clarithromycin, one (1.9%) to amoxicillin and three (5.5%) to ciprofloxacin. These indices of resistance are considered satisfactory and show that all of these antibiotics can be used in the empirical therapy. Conclusion: The antibiotics amoxicillin and clarithromycin are still a good option for first line anti-H. pylori treatment in the population of Southern Brazil.

scholarly journals The Magnitude and associated factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji Hospital, Southeast Ethiopia

2020 ◽  
Author(s):  
Dagaga Goboto Kenea ◽  
Mesfin Negawo ◽  
Firaol Kitila Lemessa ◽  
Solomon Tejineh
Keyword(s):  
Helicobacter Pylori ◽  
Alcohol Drinking ◽  
Intestinal Parasites ◽  
Helicobacter Pylori Infection ◽  
P Value ◽  
Cross Sectional ◽  
Gastrointestinal Complications ◽  
Ulcer Disease ◽  
Southeast Ethiopia ◽  
H Pylori

Abstract Background: Helicobacter pylori infection is the most common chronic bacterial infection and there were approximately 4.4 billion individuals with H pylori infection worldwide. Among those, hundreds of millions of people develop peptic ulcer disease during their lifetime and still tens of millions might progress to gastric cancer. Hence, early information is very important to prevent upper gastrointestinal complications. Consequently, the current study aimed to assess the magnitude and associated risk factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji hospital, Southeast Ethiopia.Methods: A hospital-based cross-sectional study involving 348 adult dyspeptic patients attending Bokoji hospital was carried out from July 16 to October 31, 2019. About 50 mg of fresh stool and 60 µl of capillary blood were collected from each dyspeptic patient and analyzed for detection of Helicobacter pylori antigens, presence of intestinal parasites and ABO blood grouping respectively. Data were entered using Epi Info 7 and Statistical analysis was done using SPSS version 21 and a p-value less than 0.05 was considered as statistically significant.Results: The overall magnitude of Helicobacter pylori infection was 47.7%. The magnitude of H. pylori infection was almost two times higher in patients who do not have a habit of handwashing after toilet visit than those who wash their hand's habit of handwashing after visiting toilet (AOR 2.241, 95% CI (1.410, 3.563) and alcohol drinking habit (AOR 1.796, 95% CI (1.087, 2.968). Conclusions: The magnitude of H. pylori was high in the study area and associated with handwashing habits after toilet use and alcohol drinking habits. Therefore, the community could be educated on the handwashing habit to minimize H. pylori infections.

scholarly journals Effect of Helicobacter pylori infection on the course of nonalcoholic fatty liver disease

2019 ◽  
pp. 90-94
Author(s):  
L. B. Lazebnik ◽  
L. V. Tarasova ◽  
E. A. Komarova ◽  
E. I. Busalayeva
Keyword(s):  
Helicobacter Pylori ◽  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Helicobacter Pylori Infection ◽  
Course Of Disease ◽  
Nonalcoholic Fatty Liver ◽  
The World ◽  
H Pylori

The prevalence of nonalcoholic fatty liver disease (NAFLD) in the world steadily increasеs, turning it into a most prevalent liver disease in the last decade. NAFLD is a multidisciplinary problem, it attracts the attention of specialists of different specialities. Especially interesting is the clarification of the main links of the pathogenesis of nonalcoholic fatty liver disease, including the effect of endogenous microflora on the occurrence and course of disease. Modern information is represented in the review, it confirm the association between Helicobacter pylori infection (H. pylori) and NAFLD. It has been proven that successful eradication of H. pylori detaines the fibrosis in the liver, reduces the level of proinflammatory markers, and improves insulin resistance.

Low Incidence of Helicobacter pylori Infection in Children With Recurrent Abdominal Pain in Philadelphia

PEDIATRICS ◽  
1995 ◽  
Vol 95 (4) ◽  
pp. 618-618
Author(s):  
Uwe Blecker ◽  
Devendra I. Mehta ◽  
Sophie Lanciers ◽  
Idris D. Dahodwala ◽  
Emanuel Lebenthal
Keyword(s):  
Helicobacter Pylori ◽  
Abdominal Pain ◽  
Young Children ◽  
Recurrent Abdominal Pain ◽  
Helicobacter Pylori Infection ◽  
Antral Gastritis ◽  
The World ◽  
Low Incidence ◽  
H Pylori

Reports from many parts of the world show that Helicobacter pylori infection is widely distributed geographically.1 Both chronic active (antral) gastritis and H pylori colonization are common, even in an asymptomatic population2 and H pylori gastritis has been recognized as an important cause for recurrent abdominal pain (RAP) in children.3 Although the prevalence of H pylori positivity increases with age,4 an important number of relatively young children have been shown to be already infected with this bacteria.5

scholarly journals Helicobacter Pylori Infection And Gastric Cancer: Is It Our National Problem?

2018 ◽  
Vol 36 (2) ◽  
pp. 70-76 ◽  
Author(s):  
M Mizanur Rahman ◽  
Shahjadul Alam ◽  
Abu Mohammad Khaled Iqbal ◽  
Md Monoar Hossain ◽  
Abu Mohammad Kawser Sarker ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Current Knowledge ◽  
Large Body ◽  
High Prevalence ◽  
The World ◽  
Leading Position ◽  
The Common ◽  
H Pylori

Gastric cancer is a leading cause of cancer death worldwide. In Bangladesh it ranks a leading position among the cancers patients. A large body of evidence supports a causal role of Helicobacter pylori in the majority of gastric malignancies. Scientists throughout the world explored and reached to the understanding about the pathogenesis of their relationship, but much remains to be learned. Moreover, because of the high prevalence of infection, the lack of definitive trials, and the challenges of H. pylori treatment, there remains a debate regarding the consensus on the role of routine screening and treatment of this infection to prevent cancer. This article reviews the current knowledge on H. pylori and its role for gastric cancer, present status of Bangladesh and a recommendation for reduction of the infectivity among the common population.J Bangladesh Coll Phys Surg 2018; 36(2): 70-76

scholarly journals Effectiveness of Rapid Urease Diagnostic Test in Diagnosing Helicobacter Pylori Infection in Patients with Dyspepsia in Gastrointestinal Endoscopy Centre

2020 ◽  
Vol 21 (2) ◽  
pp. 126-129
Author(s):  
Hasan Maulahela ◽  
Ari Fahrial Syam ◽  
Murdani Abdullah
Keyword(s):  
Helicobacter Pylori ◽  
Predictive Value ◽  
Gastrointestinal Endoscopy ◽  
Diagnostic Tools ◽  
Rapid Urease Test ◽  
World Population ◽  
Urease Test ◽  
The World ◽  
H Pylori ◽  
Histopathology Examination

Background: Helicobacter pylori is one of the most important infectious agents in the world. These bacteria infect 50% of the world population. Gastritis due to H. Pylori has been associated with the incidence of peptic ulcer, B cell primary lymphoma in the stomach, and gastric carcinoma. In dyspepsia, eradication of H. Pylori helps symptoms improvement and treatment cost efficiency. This study aimed to evaluate urease test in diagnosing H. Pylori infection in dyspepsia patients. It is expected that we could obtain a scientific evidence which can become the basis of routine use of urease examination in diagnosing H. Pylori  infection.Method: This study used diagnostic study design. This study was performed in adult dyspepsia patients who underwent endoscopy examination in Gastrointestinal Endoscopy Centre Cipto Mangunkusumo General Hospital in January – November 2018. One biopsy sample was intended for rapid urease test using Helicotec which was performed according to the standard procedure and was interpreted 2 hours later. Biopsy for histopathological examination was preserved in formalin solution and sent to Histopathology Department for analysis and identification of H. Pylori bacteria. Results: Prevalence of H. pylori infection based on histopathology examination was 7.2%. From seven positive results in histopathology examination, four samples were Helocitec positive. The sensitivity and specificity of Helicotec was 57.1% and 98.9%. The positive predictive value and negative predictive value were 80% and 96.7%. Conclusion: Rapid urease examination using Helicotec is one of H. pylori diagnostic tools that is good enough to diagnose faster and cheaper. Interpretation of rapid urease test also need to consider clinical condition of patients who are tested.

scholarly journals Non-invasive stool antigen test for screening of Helicobacter pylori infection and assessing efficacy of treatment in patients with peptic ulcer

2013 ◽  
Vol 2 (1) ◽  
pp. 28-33
Author(s):  
Rezina Karim ◽  
SM Moslehuddin Ahmed ◽  
Fahmida Begum
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Helicobacter Pylori Infection ◽  
World Population ◽  
Antigen Test ◽  
Stool Antigen Test ◽  
Non Invasive ◽  
Stool Antigen ◽  
H Pylori ◽  
Efficacy Of Treatment

Helicobacter pylori infection is one of the most common infections in humans, with an estimated 50% of the world population being infected.  The infection is strongly associated with chronic gastritis, peptic ulcer, adenocarcinoma and non-Hodgkin’s lymphoma of stomach. The prevalence of infection is high in developing countries, demanding a reliable diagnostic and treatment method. The present study was designed to investigate the monoclonal antibody-based H. Pylori stool antigen test to screen H. pylori infection and assess efficacy of treatment in patients with peptic ulcer. A total of 89 patients who underwent upper gastrointestinal endoscopy from July 2007 to June 2008 at Bangabandhu Sheikh Mujib Medical University Hospital, Dhaka, Bangladesh were included in the study. Endoscopic findings showed that out of 89 patients, 54 (60.7%) had duodenal ulcers, 24 (27%) had antral erosion and 5 (5.6%) had gastric ulcers. With RUT (rapid urease test) and histopathology of biopsy samples of 89 patients, 78 (87.6%) patients were found to be H. pylori positive. Stool antigen test was positive in 72 (92.3%) out of 78 H. pylori positive patients. The monoclonal stool antigen test (SAT) revealed 92.3% sensitivity and specificity of 100% before treatment. Among 52 follow-up patients (after treatment), 5 (9.6%) patients were detected positive by histology, RUT and stool antigen test, and 35 (67.3%) patients were negative by 3 tests. So the monoclonal SAT revealed 100% sensitivity and 100% specificity after treatment. The monoclonal stool antigen test is highly sensitive and a specific tool for diagnosis of H. pylori infection before therapy and can assess the success of eradication after therapy. It also offers the advantage of specificity and reliability over the invasive test.  It is easy and quick to use, non-invasive and does not require any special technology.South East Asia J Public Health | Jan-June 2012 | Vol 2 Issue 1 | 28-33 DOI: http://dx.doi.org/10.3329/seajph.v2i1.15262

scholarly journals Errors in the diagnosis and treatment of Helicobacter pylori infection: in anticipation of new conciliation documents

2021 ◽  
pp. 5-14
Author(s):  
D. S. Bordin
Keyword(s):  
Helicobacter Pylori ◽  
Clinical Practice ◽  
Helicobacter Pylori Infection ◽  
Diagnosis And Treatment ◽  
High Prevalence ◽  
H Pylori ◽  
European Registry

The high prevalence of H. pylori and diseases caused by this infection determine the relevance of discussing the problems of its diagnosis and treatment on the eve of the emergence of new international and domestic agreements. Studies published in recent years, including articles on the materials of the European Registry on the management of Helicobacter pylori infection (Hp-EuReg), provide a rich background for the analysis of errors in diagnosis and treatment of this infection, and the development of approaches to optimize clinical practice.

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