scholarly journals Large Cell Neuroendocrine Cancer (LCNEC) of Uterine Cervix

1970 ◽  
Vol 3 (1) ◽  
pp. 36-38 ◽  
Author(s):  
Gehanath Baral ◽  
Reetu Sharma
Keyword(s):  
Cervical Cancer ◽  
Uterine Cervix ◽  
Systemic Treatment ◽  
Large Cell ◽  
Cell Type ◽  
Rare Type ◽  
Papilloma Virus ◽  
Neuroendocrine Cancer ◽  
Polypoid Growth

A rare type of cervical cancer was encountered as a neuroendocrine cancer of cervix. Clinically, the patient presented with bleeding per vagina. She refused biopsy in her first visit and did not come for follow up. However, after few months she came and since there was a polypoid growth from cervix, she was advised to undergo hysterectomy. Histopathologically, it was diagnosed as large cell type of neuroendocrine cancer. Multimodality systemic treatment was offered as per literature. Ibrahim Med. Coll. J. 2009; 3(1): 36-38 Key words: Uterine cervix, neuroendocrine cancer (NEC), human papilloma virus (HPV)   doi: 10.3329/imcj.v3i1.2919

scholarly journals Scalp Metastasis of Cervical Cancer With Favorable Outcome

2020 ◽  
Vol 8 (3) ◽  
pp. 333-335
Author(s):  
Elham Saffarieh ◽  
Setare Nassiri ◽  
Maedeh Brahman ◽  
Soheila Amini Moghaddam ◽  
Shima Hosseini
Keyword(s):  
Cervical Cancer ◽  
Multidisciplinary Approach ◽  
Uterine Cervical Cancer ◽  
Radical Excision ◽  
Hematogenous Spread ◽  
Papilloma Virus ◽  
Case Presentation ◽  
Frontal Part ◽  
Scalp Metastasis

Introduction: Carcinoma of the uterine cervix is the most common gynecological malignancies in developing countries. Human papilloma virus is known as the main etiology. In addition, the spread of uterine cervical cancer often occurs through direct local extension and the lymphatics although the hematogenous spread is uncommon. Further, the scalp metastasis of cervical cancer is extremely rare. Case Presentation: In this regard, a 50-year-old woman with scalp metastasis of previous cervical cancer was discussed in the present study. She was suffering from a fast-growing and painful nodule, located on the frontal part of the scalp as a sole site of metastasis. A multidisciplinary approach was considered for her, which consisted of radical excision, followed by radiotherapy and chemotherapy. Given the lack of abundant evidence for the efficacy of this treatment, our patient has fortunately survived for more than two years. Conclusions: During the follow-up period after the completion of treatment, it is not sensible to only focus on the primary site of the tumor and thus entire examination is mandatory in this regard.

X-ray treatment for uterine cervix cancers

1927 ◽  
Vol 23 (11) ◽  
pp. 1181-1181
Author(s):  
H. Martius
Keyword(s):  
Cervical Cancer ◽  
Cancer Treatment ◽  
Uterine Cervix ◽  
X Ray ◽  
Current State

The author summarizes the current state of the issue of cervical cancer treatment with Rntgen's and radium rays. At 5-year follow-up, this treatment yields, according to different authors, from 40.5 to 55.6% of permanent cures in operable cases and from 10.2 to 16.6% in non-operable cases.

scholarly journals Different Risk Factors Associated with Persistence or Regression of Squamous Intraepithelial Lesions of Cervix under Rural Conditions in India

2020 ◽  
Author(s):  
Jata Shanker Misra ◽  
Anand Narian Srivastava ◽  
Shivani Singh
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
Uttar Pradesh ◽  
Squamous Intraepithelial Lesions ◽  
Cytological Examination ◽  
Papilloma Virus ◽  
Factors Associated ◽  
Intraepithelial Lesions ◽  
Rule Out

Introduction: In many Human Papilloma Virus (HPV) negative women, the Squamous Intraepithelial Lesions (SIL) of cervix often show persistence or progression of the lesion on follow-up which shows involvement of other risk factors of carcinoma cervix. Aim: The aim of the study was to evaluate the different risk factors of cervical cancer in persistent, progressed and regressed cases of SIL to identify the prominent ones among them. Materials and Methods: The study had been of a screening type for early detection of cervical cancer and it was done in the women population of west Lucknow, Uttar Pradesh, India (May, 2013-February, 2020). Cervical smears were collected in 2949 women attending the camps whose cytological examination revealed 498 cases of SIL and follow-up was available in 254 of them done through home visits after 1-4 years. Persistence of SIL was seen in 60 women on follow-up while in the remaining 194, the SIL had regressed to normal. The percentage of different risk factors seen with the persistence or regression of SIL was studied. Results: Among the different risk factors identified, prominent were of young age between 16-30 years with vaginal discharge and their percentage were insignificantly higher with persistence of SIL than in the regression group. Multiparity was also highly associated with both persistence and regression of SIL. The erosion of cervix was significantly associated with SIL persistence while associated inflammation was insignificantly higher in persistent than in the regression group. The percentage of all these factors except erosion of cervix was found higher in HPV- positive than in the HPV negative women. Conclusion: It appears that all the identified risk factors are present both in persistent and regression group but their percentage is higher with persistence of SIL. Hence, presence of any of these factors in these two groups should be viewed with caution to rule out any progression/recurrence of SIL.

scholarly journals Complete Surgical Excision Is Essential for the Management of Patients With Breast Implant–Associated Anaplastic Large-Cell Lymphoma

2016 ◽  
Vol 34 (2) ◽  
pp. 160-168 ◽  
Author(s):  
Mark W. Clemens ◽  
L. Jeffrey Medeiros ◽  
Charles E. Butler ◽  
Kelly K. Hunt ◽  
Michelle A. Fanale ◽  
...  
Keyword(s):  
Anaplastic Large Cell Lymphoma ◽  
Cell Lymphoma ◽  
Breast Implant ◽  
Breast Implants ◽  
Surgical Excision ◽  
Large Cell ◽  
Rare Type ◽  
Complete Surgical Excision ◽  
Large Cell Lymphoma

Purpose Breast implant–associated anaplastic large-cell lymphoma (BI-ALCL) is a rare type of T-cell lymphoma that arises around breast implants. The optimal management of this disease has not been established. The goal of this study is to evaluate the efficacy of different therapies used in patients with BI-ALCL to determine an optimal treatment approach. Patients and Methods In this study, we applied strict criteria to pathologic findings, assessed therapies used, and conducted a clinical follow-up of 87 patients with BI-ALCL, including 50 previously reported in the literature and 37 unreported. A Prentice, Williams, and Peterson model was used to assess the rate of events for each therapeutic intervention. Results The median and mean follow-up times were 45 and 30 months, respectively (range, 3 to 217 months). The median overall survival (OS) time after diagnosis of BI-ALCL was 13 years, and the OS rate was 93% and 89% at 3 and 5 years, respectively. Patients with lymphoma confined by the fibrous capsule surrounding the implant had better event-free survival (EFS) and OS than did patients with lymphoma that had spread beyond the capsule (P = .03). Patients who underwent a complete surgical excision that consisted of total capsulectomy with breast implant removal had better OS (P = .022) and EFS (P = .014) than did patients who received partial capsulectomy, systemic chemotherapy, or radiation therapy. Conclusion Surgical management with complete surgical excision is essential to achieve optimal EFS in patients with BI-ALCL.

scholarly journals One Case of Interventional Chemoembolization Treatment of Small Cell Neuroendocrine Cervical Cancer

2018 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Cervical Cancer ◽  
Large Cell ◽  
Small Cell ◽  
Endocrine Tumors ◽  
Obvious Effect ◽  
Typical Carcinoid ◽  
Neuroendocrine Cancer ◽  
Pancreatic Endocrine Tumors ◽  
Low Incidence ◽  
Surgical Conditions

Small cell neuroendocrine cervical cancer (SCNEC) is some kind of rare malignant cancer of the cervix area. In 1997, according to the research of International Cancer Institute and the American Association of Pathology, the pancreatic endocrine tumors can be sorted into four types by the morphological similarity compared with tumors of the same type in the lung: typical carcinoid, non-typical carcinoid, large cell neuroendocrine cancer, and small cell neuroendocrine cancer, in which the last one is the most previaling. The SCNEC recurs much more often and its distant metastasis is more common in the lungs, brain and liver[1][2]. It characterizes low incidence and few cases, and a retrospective study is commonly used. Without clinical experience, there have been no fair treatment so far. A patient diagnosed as SCNEC A2 period was treated in our hospital, and uterine artery embolization chemotherapy, a new treatment, was taken to her. Consequently, the treatment worked, creating significant surgical conditions for her. Moreover, postoperative examination showed obvious effect of this treatment. The case report is as follows:

A case of large cell neuroendocrine cancer of the uterine cervix

2017 ◽  
Vol 56 (5) ◽  
pp. 244-249
Author(s):  
Rie MIURA ◽  
Masayuki FUTAGAMI ◽  
Yoshihito YOKOYAMA ◽  
Kiyoshi TONE ◽  
Noriko KATO ◽  
...  
Keyword(s):  
Uterine Cervix ◽  
Large Cell ◽  
Neuroendocrine Cancer
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