scholarly journals Prevalence and Antimicrobial Susceptibility Pattern of Klebsiella Pneumoniae Isolated from Various Clinical Specimens in a Tertiary Care Hospital in Bangladesh

2020 ◽  
Vol 32 (2) ◽  
pp. 95-99
Author(s):  
Suraiya Jahan Sonia ◽  
Shadia Afroz ◽  
Md Rasheduzzaman ◽  
Kazi Hafiz Uddin ◽  
SM Shamsuzzaman
Keyword(s):  
Antimicrobial Susceptibility ◽  
Continuous Monitoring ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Clinical Specimens ◽  
Antimicrobial Susceptibility Pattern ◽  
Wound Swab ◽  
Causative Agents ◽  
Medicine Today

Introduction:Klebsiella pneumoniae are common causative agents of various infections and are of great concern for developing resistance against commonly prescribed antibiotics. This study gives an account of isolation of K. pneumoniae from various clinical specimens and their antimicrobial susceptibility, in a tertiary care hospital of Bangladesh. Materials and Methods: Various clinical specimens like urine, wound swab, sputum, blood and endotracheal aspirates were collected and processed for isolation of K. pneumoniae followed by their antimicrobial susceptibility testing. Results: Among the 316 samples that yielded culture positivity, K. pneumoniae were identified as second most common organism. The highest yield of K. pneumoniae (37.33%) were observed from wound swab followed by sputum (26.67%). Most of the isolates were resistant to sulphamethoxazole-trimethoprim (90.67%) and ceftriaxone (90.67%) followed by cefotaxime (89.33%), ceftazidime (89.33%) and cefuroxime (89.33%). The most sensitive antibiotic for the isolates was tigecycline. Conclusion: Isolated K. pneumoniae showed resistance to commonly prescribed antibiotics, which is very alarming and showing the importance on continuous monitoring and strict antimicrobial policy. Medicine Today 2020 Vol.32(2): 95-99

ANTIBIOTIC SUSCEPTIBILITY PATTERN OF STAPHYLOCOCCOUS AUREUS ISOLATED FROM VARIOUS CLINICAL SPECIMENS OF TERTIARY CARE HOSPITAL IN TIRUPATI.

2021 ◽  
pp. 14-15
Author(s):  
Indira Ananthapadmanab asamy ◽  
V. Pavani Sai Mounika ◽  
K. Vijayakumar ◽  
C.H. Srinivasa Rao
Keyword(s):  
Antimicrobial Susceptibility ◽  
Tertiary Care ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Clinical Specimens ◽  
Antimicrobial Susceptibility Pattern ◽  
Wide Range ◽  
Life Threatening ◽  
Mrsa Infection ◽  
Systemic Infections

INTRODUCTION: Staphylococcus aureus causes a wide range of infections including skin and soft tissue infections to life-threatening systemic infections like sepsis, endocarditis. This study ais to evaluate the antimicrobial susceptibility pattern of S.aurues among various clinical specimens. METHODS: The study included 326 S.aurues, isolated from various clinical specimens which were subjected to antimicrobial susceptibility testing as per CLSI guidelines. RESULTS: Among the 326 isolates, the highest were from pus specimens (47.85%), and was from Orthopaedics department (28.53%). Among the isolates, 219 (67.17%) were Methicilin resistant. All isolates were sensitive to Vancomycin, and all urine isolates were sensitive to Nitrofurantoin. The highest resistance was towards Penicillin (87.42%), Erythromycin (85.28), and Ciprooxacin (83.13%). CONCLUSION: The most effective way to prevent MRSA infection in every hospital is by performing continuous surveillance of antibiotic resistance and by following an effetive antibiotic policy.

scholarly journals Neonatal Septicaemia: A Hospital Based Study in Eastern Nepal

2004 ◽  
Vol 43 (155) ◽  
Author(s):  
Dr. Basudha Khanal ◽  
M Shariff ◽  
M Deb
Keyword(s):  
Antimicrobial Susceptibility ◽  
Tertiary Care ◽  
Neonatal Morbidity ◽  
Premature Delivery ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Candida Spp ◽  
Antimicrobial Susceptibility Pattern ◽  
Neonatal Septicaemia ◽  
Causative Agents

Septicaemia  is  a  major  cause  of  neonatal  morbidity  and  mortality.  Premature  rupture  of  membrane, premature delivery, low birth weight and hospitalisation of the neonate are some of the predisposing factors, which influence the onset of infection and its outcome.   Depending on the time of onset and the causative factors, a wide variety of organisms are implicated in neonatal septicaemia.   The blood culture takes a minimum of 48 hrs to arrive at a definitive diagnosis. A prompt management of such cases along with empirical antibiotic therapy remains the mainstay of management. Hence, knowledge about the organisms prevalent in a particular hospital and their antibiotic susceptibility pattern is an important prerequisite. The study was carried out at the B.P. Koirala institute of health sciences, a tertiary care hospital, in Eastern Nepal for a period of 3-years from 1998 to 2001. Blood samples from 1567 neonates with suspected septicaemia were cultured using standard microbiological technique. 540 (35%) samples were culture positive. Gram- positive bacteria (74%) were more common than Gram-negative bacteria (27%). Staph aureus   (60%) was the most common bacterial isolate. Resistant to ampicillin was seen but most were susceptible to other antimicrobial  including  gentamicin,  amikacin,  cefotaxime,  and  ciprofloxacin.  Positivity  rate  decreased  in the 3rd  year to 25% as against first two years of 41% and 47% respectively, which was, attributed to training and implementation of various measures of infection control practices. Candida spp was not observed during the period of study. It was concluded that a continuous surveillance of the causative agents and their antimicrobial susceptibility pattern is required to control the infection in the hospital neonatal unit.Key Words: Neonatal septicaemia, Organisms, Antimicrobial susceptibility pattern. 

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