Clinical Value of Endobronchial Ultrasound Findings for Predicting Nodal Metastasis in Patients with Suspected Lymphadenopathy: A Prospective Study

Many patients presenting with haematuria undergo intravenous urography, renal tract ultrasound and cystoscopy. Renal tract ultrasound includes imaging of the bladder, which can significantly increase scan times by necessitating bladder filling, which can impact negatively on appointment scheduling. Little published literature exists on whether ultrasound of the bladder in the presence of haematuria is of any clinical benefit. This study aims to redress this by comparing bladder ultrasound to the gold standard of cystoscopy and also by assessing temporal implications in this patient group. A prospective study was undertaken where 96 consecutive urology-referred patients had their bladder ultrasound findings compared with the findings of cystoscopy under the headings of mass, trabeculation, diverticulum, stone and fistula. Ultrasound had poor sensitivity (47.8%), but good specificity (94.5%) in detecting the predefined bladder pathologies with a poor Kappa score of 0.33 when compared with cystoscopy. In addition, there was a significant time burden placed on the list by including bladder scanning as part of the renal tract sonographic assessment. In conclusion, bladder ultrasound is not shown to be a clinically useful adjunct to cystoscopy for the detection of bladder pathology. We would recommend that, in the setting of haematuria, ultrasound be used only for upper tract assessment.

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Cutaneous malignant melanoma in West Yorkshire: Ii. A prospective study of recurrence and prediction of lymph nodal metastasis

British Journal of Cancer ◽

10.1038/bjc.1984.137 ◽

1984 ◽

Vol 50 (1) ◽

pp. 35-43 ◽

Cited By ~ 15

Author(s):

J Eastwood ◽

T G Baker

Keyword(s):

Malignant Melanoma ◽

Prospective Study ◽

Nodal Metastasis ◽

Cutaneous Malignant Melanoma ◽

Lymph Nodal Metastasis ◽

A Prospective Study

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Clinical Value of Electrodiagnostic Testing Following Repair of Peripheral Nerve Lesions: A Prospective Study

Journal of Hand Surgery (European Volume) ◽

10.1054/jhsb.2002.0778 ◽

2002 ◽

Vol 27 (4) ◽

pp. 345-349 ◽

Cited By ~ 8

Author(s):

Th. H. J. VAN DE KAR ◽

J. B. JAQUET ◽

J. MEULSTEE ◽

C. B. H. MOLENAAR ◽

R. J. SCHIMSHEIMER ◽

...

Keyword(s):

Peripheral Nerve ◽

Prospective Study ◽

Ulnar Nerve ◽

Motor Score ◽

Clinical Value ◽

Secondary Surgery ◽

Electrodiagnostic Testing ◽

Peripheral Nerve Lesions ◽

Sensory Recovery ◽

A Prospective Study

This study prospectively assessed the level of correlation between functional and electrophysiological recovery after median and ulnar nerve lacerations. Motor and sensory recovery were recorded clinically and electrophysiologically every 3 months in 24 patients with 29 complete median or ulnar nerve lacerations. The strength of agreement between the clinical motor score and the electrophysiological score was “fair”, but in 41% a discrepancy was identified (kappa factor 0.39). Regeneration was not detected earlier by electrophysiology than by a thoroughly performed clinical evaluation. This suggests that electrophysiologic testing is of value as an adjunct to clinical assessment for evaluating cases in which there is clinical doubt as to the progress of regeneration and secondary surgery is contemplated.

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A prospective study of the clinical value and accuracy of grey scale ultrasound in detecting gallstones

British Journal of Surgery ◽

10.1002/bjs.1800650512 ◽

1978 ◽

Vol 65 (5) ◽

pp. 330-333 ◽

Cited By ~ 19

Author(s):

A. J. McKay ◽

J. G. Duncan ◽

C. W. Imrie ◽

S. N. Joffe ◽

L. H. Blumgart

Keyword(s):

Prospective Study ◽

Clinical Value ◽

Grey Scale ◽

A Prospective Study

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Diagnostic Value of a New Cryoprobe for Peripheral Pulmonary Lesions: A Prospective Study

10.21203/rs.3.rs-1010979/v1 ◽

2021 ◽

Author(s):

Midori Tanaka ◽

Yuji Matsumoto ◽

Tatsuya Imabayashi ◽

Takuya Kawahara ◽

Takaaki Tsuchida

Keyword(s):

Prospective Study ◽

Diagnostic Yield ◽

Diagnostic Value ◽

Lesion Size ◽

Endobronchial Ultrasound ◽

Pulmonary Lesions ◽

Single Use ◽

Peripheral Pulmonary Lesions ◽

A Prospective Study ◽

Established Technique

Abstract Background: Cryobiopsy is an established technique that yields larger and higher-quality samples than does a forceps biopsy. However, it remains underutilised in the diagnosis of peripheral pulmonary lesions (PPLs), mainly because of difficulties in handling conventional cryoprobes. A recently introduced single-use cryoprobe with a smaller diameter and more flexibility than conventional ones may improve its diagnostic ability for PPLs. We conducted this prospective study to evaluate the feasibility of transbronchial cryobiopsy in the diagnoses of PPLs, using a new 1.7-mm cryoprobe. Methods: The study included patients with PPLs less than 30 mm in diameter scheduled to undergo bronchoscopy. All the procedures were performed using a combination of virtual bronchoscopic navigation, radial endobronchial ultrasound (R-EBUS) and X-ray fluoroscopy, and all the samples were collected using the cryoprobe alone. Thereafter, we assessed the diagnostic outcomes and safety profiles.Results: A total of 50 patients were enrolled and underwent cryobiopsy. The median lesion size was 20.8 mm (range, 8.2–29.6 mm), and the negative bronchus sign was seen in 34% of lesions. The diagnostic yield was 94% (95% confidence interval, 83.5–98.8%). A positive bronchus sign had a significantly higher diagnostic yield than did a negative bronchus sign (100% vs. 82.4%; P=0.035). The yield was achieved regardless of other variables, including lesion size, location, and R-EBUS findings. The major complications were mild and moderate bleeding in 28% and 62% of patients, respectively. Pneumothorax was identified in one patient.Conclusion: Transbronchial cryobiopsy using the new 1.7-mm cryoprobe is a feasible procedure that has the potential to increase the diagnostic accuracy for PPLs.Trial Registration: Japan Registry of Clinical Trials, jRCT1032200065. Registered 8 July 8 2020, https://jrct.niph.go.jp/en-latest-detail/jRCT1032200065

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