scholarly journals Predictive Role of Lung Injury Prediction Score in the Development of Acute Respiratory Distress Syndrome in Korea

2021 ◽  
Vol 62 (5) ◽  
pp. 417
Author(s):  
Beong Ki Kim ◽  
Sua Kim ◽  
Chi Young Kim ◽  
Yu Jin Kim ◽  
Seung Heon Lee ◽  
...  
2016 ◽  
Vol 44 (12) ◽  
pp. 2182-2191 ◽  
Author(s):  
Graciela J. Soto ◽  
Daryl J. Kor ◽  
Pauline K. Park ◽  
Peter C. Hou ◽  
David A. Kaufman ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Zachary M. Bauman ◽  
Marika Y. Gassner ◽  
Megan A. Coughlin ◽  
Meredith Mahan ◽  
Jill Watras

Background. Lung injury prediction score (LIPS) is valuable for early recognition of ventilated patients at high risk for developing acute respiratory distress syndrome (ARDS). This study analyzes the value of LIPS in predicting ARDS and mortality among ventilated surgical patients.Methods. IRB approved, prospective observational study including all ventilated patients admitted to the surgical intensive care unit at a single tertiary center over 6 months. ARDS was defined using the Berlin criteria. LIPS were calculated for all patients and analyzed. Logistic regression models evaluated the ability of LIPS to predict development of ARDS and mortality. A receiver operator characteristic (ROC) curve demonstrated the optimal LIPS value to statistically predict development of ARDS.Results. 268 ventilated patients were observed; 141 developed ARDS and 127 did not. The average LIPS for patients who developed ARDS was8.8±2.8versus5.4±2.8for those who did not (p<0.001). An ROC area under the curve of 0.79 demonstrates LIPS is statistically powerful for predicting ARDS development. Furthermore, for every 1-unit increase in LIPS, the odds of developing ARDS increase by 1.50 (p<0.001) and odds of ICU mortality increase by 1.22 (p<0.001).Conclusion. LIPS is reliable for predicting development of ARDS and predicting mortality in critically ill surgical patients.


Perfusion ◽  
2020 ◽  
pp. 026765912092563
Author(s):  
Sudhir Krishnan ◽  
Guramrinder Singh Thind ◽  
Mona Soliman ◽  
Leslie Tolle ◽  
Eduardo Mireles-Cabodevila ◽  
...  

Introduction: An upsurge of e-cigarette, or vaping, product use–associated lung injury has been reported in the United States. The potential role of extracorporeal life support in e-cigarette, or vaping, product use–associated lung injury merits consideration. Case report: We present a case of vaping-induced severe acute respiratory distress syndrome that was salvaged with extracorporeal life support and had excellent recovery. Discussion: The mechanistic reasons for the sudden outbreak of e-cigarette, or vaping, product use–associated lung injury are under active investigation. A predominantly diffuse, bilateral pattern of lung injury has been reported, with some cases meeting the criteria for severe acute respiratory distress syndrome. To date, 68 deaths from e-cigarette, or vaping, product use–associated lung injury have been confirmed by the centers of disease control. However, resolution of lung injury has been reported in most cases, thereby justifying candidacy for extracorporeal life support, if required. Conclusion: Extracorporeal life support can be successfully utilized as a bridge to recovery in vaping-induced severe acute respiratory distress syndrome.


2016 ◽  
Vol 311 (4) ◽  
pp. L714-L718 ◽  
Author(s):  
Amit Gaggar ◽  
Rakesh P. Patel

The major role of red blood cells (RBCs) is to deliver oxygen and remove carbon dioxide within organisms through the unique properties of hemoglobin. Although beneficial within RBCs, when outside hemoglobin and its breakdown products (heme, iron) induce proinflammatory responses affecting various cellular responses. Although these effects are considered to be prominent in disorders with increased hemolysis, recent evidence suggests that this process may be active in nonhemolytic disorders such as acute lung injury/acute respiratory distress syndrome. This perspectives article focuses on data related to red cell products in nonhemolytic disorders and the potential to target these factors in acute lung injury/acute respiratory distress syndrome.


10.1186/rr193 ◽  
2002 ◽  
Vol 3 (1) ◽  
Author(s):  
Panagiotis Agouridakis ◽  
Despina Kyriakou ◽  
Michael G Alexandrakis ◽  
Athanasios Prekates ◽  
Kostas Perisinakis ◽  
...  

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