scholarly journals Slow Breathing Training Reduces Resting Blood Pressure and the Pressure Responses to Exercise

2015 ◽  
pp. 673-682 ◽  
Author(s):  
C. U. JONES ◽  
B. SANGTHONG ◽  
O. PACHIRAT ◽  
D. A. JONES
Keyword(s):  
Blood Pressure ◽  
Pressor Response ◽  
Autonomic Control ◽  
Handgrip Exercise ◽  
Breathing Training ◽  
Hand Grip ◽  
Pressor Responses ◽  
Resting Blood Pressure ◽  
Slow Breathing ◽  
Inspiratory Load

Slow breathing training reduces resting blood pressure, probably by modifying central autonomic control, but evidence for this is lacking. The pressor response to static handgrip exercise is a measure of autonomic control and the aim of this study was to determine whether slow breathing training modulates the pressor responses to exercise of untrained muscles. Twenty hypertensive patients trained for 8 weeks, 10 with unloaded slow breathing (Unloaded) and 10 breathing against an inspiratory load of 20 cm H2O (Loaded). Ten subjects were untrained controls. Subjects performed a 2 min handgrip pressor test (30 % MVC) pre- and post-training, and blood pressure and heart rate (HR) were measured before the contraction, at the end and following 2 min recovery. Resting systolic (sBP) and HR were reduced as a result of training, as reported previously. After training there was both a smaller pressor response to hand grip exercise and a more rapid recovery of sBP and HR compared to pre-training. There were no changes in the Controls and no differences between the Unloaded and Loaded groups. Combining the two training groups, the sBP response to handgrip exercise after training was reduced by 10 mm Hg (95 % CI: −7, −13) and HR by 5 bpm (95 % CI: −4, −6), all p<0.05. These results are consistent with slow breathing training modifying central mechanisms regulating cardiovascular function.

Blood pressure control in pregnant rabbits: norepinephrine and prostaglandin interactions

1984 ◽  
Vol 247 (5) ◽  
pp. R786-R791 ◽  
Author(s):  
R. Venuto ◽  
I. Min ◽  
P. Barone ◽  
A. Donker ◽  
E. Cunningham
Keyword(s):  
Blood Pressure ◽  
Pressor Response ◽  
Pressure Control ◽  
Systemic Blood Pressure ◽  
Blood Levels ◽  
Adrenergic Blockade ◽  
Resting Blood Pressure ◽  
Pge2 Concentration ◽  
The Relationship ◽  
Hypotensive Response

The relationship between norepinephrine (NE) and prostaglandins in the regulation of systemic blood pressure during pregnancy was examined in conscious rabbits. The arterial prostaglandin E2 (PGE2) concentration was higher in pregnant than in nonpregnant rabbits. Resting blood pressure was slightly lower in the gravid animals. The pressor response to incremental doses of intravenous NE was blunted in the pregnant rabbits. Meclofenamate, a cyclooxygenase inhibitor, failed to alter the resting blood pressure in either group of animals, although it reduced PGE2 levels more than 60% in the pregnant rabbits. The pressor response to NE was significantly increased only in the pregnant rabbits when the NE infusion was repeated following meclofenamate. Pregnant rabbits could also be differentiated from nonpregnant by their higher peripheral blood levels of NE and their uniform hypotensive response to alpha-adrenergic blockade. These observations define an altered responsiveness to both endogenous and exogenous NE in pregnant rabbits that appears to be related to an increase in vasodilator prostaglandins.

Pressor effect of arginine vasopressin in progressive autonomic failure

1986 ◽  
Vol 71 (2) ◽  
pp. 173-178 ◽  
Author(s):  
T. D. M. Williams ◽  
D. DaCosta ◽  
C. J. Mathias ◽  
R. Bannister ◽  
S. L. Lightman
Keyword(s):  
Blood Pressure ◽  
Arginine Vasopressin ◽  
Autonomic Failure ◽  
Pressor Response ◽  
Normal Subjects ◽  
Pressor Effect ◽  
Normal Volunteers ◽  
Pressor Responses ◽  
Transient Bradycardia ◽  
Related Increase

1. The blood pressure (BP) and heart rate (HR) responses to 5 min incremental intravenous infusions of noradrenaline (NA) and arginine vasopressin (AVP) were investigated both in patients with progressive autonomic failure (PAF) and in normal volunteers. 2. Stepwise infusion of NA at rates of 300–3000 pmol min−1 kg−1 produced a bradycardia and a dose related increase in BP in normal subjects. In subjects with PAF there was no significant HR response but the dose-BP response was shifted to the left with significant pressor responses at infusion rates of 60–300 pmol min−1 kg−1. 3. Stepwise infusion of AVP at 0.2–5.0 pmol min−1 kg−1 caused transient bradycardia but no pressor response in seven normal volunteers. Further increases in AVP infusion in three other subjects achieved plasma AVP levels as high as 3000–4000 pmol/l, and still no significant pressor response was observed. 4. Stepwise infusion of AVP at 0.05–2.0 pmol min−1 kg−1 in the eight subjects with PAF resulted in a pressor response without any change in HR. During this infusion plasma AVP increased from 0.8 ± 0.2 (mean ± se) to 30 ± 2 pmol/l. A significant pressor response was already apparent at a plasma AVP level of 5.5 ± 1.8 pmol/l.

Blood pressure changes in patients with chronic heart failure undergoing slow breathing training

2015 ◽  
Vol 25 (1) ◽  
pp. 4-10 ◽  
Author(s):  
Tomasz Drozdz ◽  
Grzegorz Bilo ◽  
Dorota Debicka-Dabrowska ◽  
Marek Klocek ◽  
Gabriella Malfatto ◽  
...  
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Chronic Heart Failure ◽  
Breathing Training ◽  
Slow Breathing ◽  
Pressure Changes

scholarly journals RELATIONSHIP OF BLOOD PRESSURE RESPONSES TO ISOMETRIC EXERCISE IN NON-HYPERTENSIVE MEDICAL STUDENTS WITH FAMILIAL HYPERTENSION

2020 ◽  
Vol 28 (4) ◽  
pp. 331-336
Author(s):  
Umema Zafar ◽  
Shafiq Ur Rahman ◽  
Omar Malik ◽  
Henna Salman
Keyword(s):  
Blood Pressure ◽  
Isometric Exercise ◽  
Cross Sectional Study ◽  
Maximum Pressure ◽  
P Value ◽  
Handgrip Exercise ◽  
Cross Sectional ◽  
Hand Grip ◽  
Type Of Exercise ◽  
Blood Pressure Responses

Background Blood pressure (BP) rises as a result of isometric exercise, but if such type of exercise is done on a regular basis both resting diastolic and systolic blood pressures (SBP and SBP) have been reported to decrease. However, the blood pressure responses to handgrip (isometric) exercise may vary. The aim of this study is to find out whether there is a significant relation between blood pressure responses due to handgrip (HG) exercise and family history of hypertension.   Methods This is cross sectional study conducted in Khyber Medical College on healthy students of first and second year MBBS. After taking informed consentand history, the students were made to perform the hand grip exercise for 5 minutes at 30 % of their maximum pressure. BP was recorded before during and after the procedure. The data was then analyzed using SPSS version 20.0 keeping, P value ? 0.05.   Result The change in SBP was significant both during (p=0.024) and after (p=0.033) hand grip exercise. The relation between 30% of maximum pressure applied and change in SBP is significant (p<0.001) in the familial hypertension present group only.   Conclusion  There was significant change in systolic blood pressure in response to handgrip exercise in the group of subjects with familial hypertension positive group. Hence concluded that a relation does exist between blood pressure responses to handgrip exercise and familial hypertension.

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