scholarly journals Microbiological Method for the Detection of Antibiotic Residues in Meat Using Mixed-Mode, Reverse-Phase and Cation-Exchange Cartridge

2004 ◽  
Vol 45 (4) ◽  
pp. 191-196 ◽  
Author(s):  
Tomoko KUSANO ◽  
Maki KANDA ◽  
Kunihiro KAMATA ◽  
Tomoyuki MIYAZAKI
Keyword(s):  
Cation Exchange ◽  
Mixed Mode ◽  
Antibiotic Residues ◽  
Microbiological Method ◽  
Reverse Phase

Review on the Application of Mixed-mode Chromatography for Separation of Structure Isoforms

2018 ◽  
Vol 20 (1) ◽  
pp. 56-60 ◽  
Author(s):  
Tsutomu Arakawa
Keyword(s):  
Ion Exchange ◽  
Mixed Mode ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Charged State ◽  
Partial Structure ◽  
Reverse Phase ◽  
Oligomer Formation ◽  
Structure Rearrangement ◽  
Disulfide Scrambling

Proteins often generate structure isoforms naturally or artificially due to, for example, different glycosylation, disulfide scrambling, partial structure rearrangement, oligomer formation or chemical modification. The isoform formations are normally accompanied by alterations in charged state or hydrophobicity. Thus, isoforms can be fractionated by reverse-phase, hydrophobic interaction or ion exchange chromatography. We have applied mixed-mode chromatography for fractionation of isoforms for several model proteins and observed that cation exchange Capto MMC and anion exchange Capto adhere columns are effective in separating conformational isoforms and self-associated oligomers.

Characterization of Retention Mechanisms in Mixed-Mode HPLC with a Bimodal Reversed-Phase/Cation-Exchange Stationary Phase

2018 ◽  
Vol 81 (3) ◽  
pp. 387-399 ◽  
Author(s):  
Elise Lemasson ◽  
Yoann Richer ◽  
Sophie Bertin ◽  
Philippe Hennig ◽  
Caroline West
Keyword(s):  
Stationary Phase ◽  
Cation Exchange ◽  
Mixed Mode ◽  
Reversed Phase ◽  
Retention Mechanisms

Phosphatidic acid-functionalized monolithic stationary phase for reversed-phase/cation-exchange mixed mode chromatography

RSC Advances ◽  
2016 ◽  
Vol 6 (103) ◽  
pp. 100891-100898 ◽  
Author(s):  
Kun Peng ◽  
Qiqin Wang ◽  
Weijia Chen ◽  
Donghai Xia ◽  
Zhengyin Zhou ◽  
...  
Keyword(s):  
Phosphatidic Acid ◽  
Stationary Phase ◽  
Cation Exchange ◽  
Mixed Mode ◽  
Pharmaceutical Compounds ◽  
Reversed Phase ◽  
Small Peptides ◽  
Wide Range ◽  
Monolithic Stationary Phase

A reversed-phase and cation-exchange mixed-mode poly(MDPA-co-EDMA) monolith was successfully prepared and applied to the separation of a wide range of analytes, such as small peptides, phenols, vitamins B, pharmaceutical compounds.

scholarly journals HPLC Separation of Acetaminophen and its Impurities Using A Mixed-mode Reversed-Phase/Cation Exchange Stationary Phase

2012 ◽  
Vol 50 (4) ◽  
pp. 335-342 ◽  
Author(s):  
O. Calinescu ◽  
I. A. Badea ◽  
L. Vladescu ◽  
V. Meltzer ◽  
E. Pincu
Keyword(s):  
Stationary Phase ◽  
Cation Exchange ◽  
Mixed Mode ◽  
Reversed Phase ◽  
Hplc Separation

Controllable preparation of a reverse-phase/hydrophilic interaction mixed-mode chromatographic stationary phase with adjustable selectivity

2018 ◽  
Vol 10 (45) ◽  
pp. 5387-5397 ◽  
Author(s):  
Chunmiao Bo ◽  
Xiaojun Dai ◽  
Weimin Chen ◽  
Rui Cao
Keyword(s):  
Block Copolymers ◽  
Stationary Phase ◽  
Mixed Mode ◽  
Hydrophilic Interaction ◽  
Reverse Phase ◽  
Separation Selectivity ◽  
Controllable Preparation

A mixed-mode stationary phase prepared by grafting block copolymers via ATRP could adjust separation selectivity by simply tuning the ratios of copolymer chains.

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