scholarly journals the benefit of tympanometry for certain ear diseases

2021 ◽  
Vol 27 (2) ◽  
pp. 60-64
Author(s):  
Adnan yaqoop ◽  
Hussam Salman ◽  
Rafid Y. Almaidi
Keyword(s):  
Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3626
Author(s):  
Yi-Chun Lin ◽  
Yuan-Yung Lin ◽  
Hsin-Chien Chen ◽  
Chao-Yin Kuo ◽  
Ai-Ho Liao ◽  
...  

The application of insulin-like growth factor 1 (IGF-1) to the round window membrane (RWM) is an emerging treatment for inner ear diseases. RWM permeability is the key factor for efficient IGF-1 delivery. Ultrasound microbubbles (USMBs) can increase drug permeation through the RWM. In the present study, the enhancing effect of USMBs on the efficacy of IGF-1 application and the treatment effect of USMB-mediated IGF-1 delivery for noise-induced hearing loss (NIHL) were investigated. Forty-seven guinea pigs were assigned to three groups: the USM group, which received local application of recombinant human IGF-1 (rhIGF-1, 10 µg/µL) following application of USMBs to the RWM; the RWS group, which received IGF-1 application alone; and the saline-treated group. The perilymphatic concentration of rhIGF-1 in the USM group was 1.95- and 1.67- fold of that in the RWS group, 2 and 24 h after treatment, respectively. After 5 h of 118 dB SPL noise exposure, the USM group had the lowest threshold shift in auditory brainstem response, least loss of cochlear outer hair cells, and least reduction in the number of synaptic ribbons on postexposure day 28 among the three groups. The combination of USMB and IGF-1 led to a better therapeutic response to NIHL. Two hours after treatment, the USM group had significantly higher levels of Akt1 and Mapk3 gene expression than the other two groups. The most intense immunostaining for phosphor-AKT and phospho-ERK1/2 was detected in the cochlea in the USM group. These results suggested that USMB can be applied to enhance the efficacy of IGF-1 therapy in the treatment of inner ear diseases.


2012 ◽  
Vol 32 (2) ◽  
pp. 142-145 ◽  
Author(s):  
B Sigdel ◽  
R Nepali

Introduction: Ear diseases are common in children mainly due to altered anatomy of Eustachian tube which is straighter in children as compared to that in adults. However, the cause of hearing loss in children is more varied, including the etiologies. This study was done to find out the pattern of ear diseases in paediatric age group attending ear, nose and throat OPD in a tertiary care centre in Pokhara, Nepal. Materials and Methods: This is a prospective study done in paediatric patients attending ENT OPD over a period of one year from January 2010 to January 2011. The diagnoses were made on the basis of history and clinical examination. Results were expressed in numbers and percentages. Results: Out of 1632 Pediatric ENT patients, 944 had ear diseases, 59.2% were males and 40.8% females. Wax (33.4%) was the commonest diagnosis followed by Chronic suppurative otitis media (24.3%) and Acute ottitis media (13%). Conclusion: Ear diseases are most common condition in ENT OPD among paediatric age group. Wax, CSOM and ASOM were the three most common ear diseases. J. Nepal Paediatr. Soc. 32(2) 2012 142-145 doi: http://dx.doi.org/10.3126/jnps.v32i2.5673


1969 ◽  
Vol 90 (5) ◽  
pp. 609-616 ◽  
Author(s):  
C. W. Gross ◽  
H. J. Bikhazi ◽  
P. W. Hoffmann
Keyword(s):  

Author(s):  
Francesca Atturo ◽  
Ginevra Portanova ◽  
Francesca Yoshie Russo ◽  
Daniele De Seta ◽  
Laura Mariani ◽  
...  

1995 ◽  
Vol 76 (1) ◽  
pp. 66-70
Author(s):  
L. G. Svatko ◽  
G. M. Chekaev ◽  
V. I. Galochkin ◽  
O. P. Prikhodko ◽  
Z. F. Polikarpova ◽  
...  

The experience of the work of the interrepublican ear-improving centre giving medical and consulting service to patients with ear diseases for a period of 30 years is presented. The structure and directions of the polyclinic department of the ear-improving centre are given, and the clinical examination using monitoring observation of the ear and vestibular function state of patients after surgical rehabilitation should be given consideration.


2002 ◽  
Vol 64 (2) ◽  
pp. 105-110 ◽  
Author(s):  
R.S.Phaneendra Rao ◽  
Malavika A. Subramanyam ◽  
N.Sreekumaran Nair ◽  
B Rajashekhar

2003 ◽  
Vol 1240 ◽  
pp. 1163-1167 ◽  
Author(s):  
M Suzuki ◽  
M.S Krug ◽  
K.C Cheng ◽  
Y Yazawa ◽  
J Bernstein ◽  
...  
Keyword(s):  

2021 ◽  
Vol 20 (1) ◽  
pp. 72-77
Author(s):  
I. A. Anikin ◽  
◽  
S. A. Eremin ◽  
A. E. Shinkareva ◽  
S. I. Sitnikov ◽  
...  

The external auditory canal is not only a part of the external ear, but also an integral part of the human auditory system, which conducts and amplifies the sound wave. In the field of otosurgery, it is often the priority access to the tympanic cavity, and therefore it is necessary to clearly understand the features of its anatomy. The dimensions and anatomy of the external auditory canal are extremely variable: the length is 2–3,5 cm, the diameter ranges from 5-9 mm, it is somewhat curved in the horizontal and frontal planes and consists of a membranous cartilaginous part and a bony part, between which there is the most the bottleneck – the isthmus. The ear canal is covered with skin, the thickness and structure of which depends on the section of the ear canal. The membranous cartilaginous section contains sebaceous and sulfur glands. Studies identify several forms of the bony part of the ear canal: conical, hourglass-shaped, ovoid, reverse conical, and cylindrical. The endoscopic scale (CES) for the visibility of the tympanic membrane was also proposed for the convenience of assessment. It has been suggested that the shape of the external auditory canal is an etiological factor in chronic otitis externa. Unambiguous interpretations of the relationship between ear diseases and the shape of the external auditory canal have not yet been obtained, but modern developments tend to consider its importance in the development of ear diseases. Clinical observations show that certain anatomical forms of it may be involved in the pathogenesis of chronic inflammation, since they interfere with proper self-cleaning.


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