scholarly journals Mechanism-Driven Metabolic Engineering for Bio-Based Production of Free R-Lipoic Acid in Saccharomyces cerevisiae Mitochondria

Author(s):  
Binbin Chen ◽  
Jee Loon Foo ◽  
Hua Ling ◽  
Matthew Wook Chang
Author(s):  
Wenqi Shi ◽  
Jie Li ◽  
Yanfang Chen ◽  
Xiaohang Liu ◽  
Yefu Chen ◽  
...  

2021 ◽  
Vol 69 (10) ◽  
pp. 3103-3113
Author(s):  
Junhua Wang ◽  
Wei Jiang ◽  
Chaojuan Liang ◽  
Linghuan Zhu ◽  
Youran Li ◽  
...  

2019 ◽  
Vol 21 (7) ◽  
pp. 1795-1808 ◽  
Author(s):  
Gregory Guirimand ◽  
Kentaro Inokuma ◽  
Takahiro Bamba ◽  
Mami Matsuda ◽  
Kenta Morita ◽  
...  

Xylitol is a major commodity chemical widely used in both the food and pharmaceutical industries.


2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiao-Jing Guo ◽  
Wen-Hai Xiao ◽  
Ying Wang ◽  
Ming-Dong Yao ◽  
Bo-Xuan Zeng ◽  
...  

Author(s):  
Jian Zha ◽  
Miaomiao Yuwen ◽  
Weidong Qian ◽  
Xia Wu

Xylose is the second most abundant sugar in lignocellulosic hydrolysates. Transformation of xylose into valuable chemicals, such as plant natural products, is a feasible and sustainable route to industrializing biorefinery of biomass materials. Yeast strains, including Saccharomyces cerevisiae, Scheffersomyces stipitis, and Yarrowia lipolytica, display some paramount advantages in expressing heterologous enzymes and pathways from various sources and have been engineered extensively to produce natural products. In this review, we summarize the advances in the development of metabolically engineered yeasts to produce natural products from xylose, including aromatics, terpenoids, and flavonoids. The state-of-the-art metabolic engineering strategies and representative examples are reviewed. Future challenges and perspectives are also discussed on yeast engineering for commercial production of natural products using xylose as feedstocks.


2020 ◽  
Vol 66 (3) ◽  
pp. 310-318
Author(s):  
Huan Lu ◽  
Yunfeng Zhang ◽  
Dan He ◽  
Xiaozhou Luo ◽  
Jiandong Huang

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