scholarly journals Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

2021 ◽  
Vol 8 ◽  
Author(s):  
Jianbo Qu ◽  
Zhi-Hao Zhang ◽  
Haitao Zhang ◽  
Zhen-Tao Weng ◽  
Jian-Yong Wang

Diethyl malonate-based fluorescent probe NE-N2H4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N2H4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N2H4 can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N2H4 might be used to monitor hydrazine in biosamples and environmental problem.

2018 ◽  
Vol 259 ◽  
pp. 233-240 ◽  
Author(s):  
Haohan Song ◽  
Junli Zhang ◽  
Xiao Wang ◽  
Yanmei Zhou ◽  
Chenggong Xu ◽  
...  

Nanomaterials ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1575
Author(s):  
Karthiga K. Anpalagan ◽  
Jimsheena V. Karakkat ◽  
Adam Truskewycz ◽  
Ahmed Al Saedi ◽  
Paul Joseph ◽  
...  

Biocompatible carbon quantum dots (CQDs) have recently attracted increased interest in biomedical imaging owing to their advantageous photoluminescence properties. Numerous precursors of fluorescent CQDs and various fabrication procedures are also reported in the literature. However; the use of concentrated mineral acids and other corrosive chemicals during the fabrication process curtails their biocompatibility and severely limits the utilization of the products in cell bio-imaging. In this study; a facile; fast; and cost-effective synthetic route is employed to fabricate CQDs from a natural organic resource; namely bread; where the use of any toxic chemicals is eliminated. Thus; the novel chemical-free technique facilitated the production of luminescent CQDs that were endowed with low cytotoxicity and; therefore; suitable candidates for bioimaging sensors. The above mentioned amorphous CQDs also exhibited fluorescence over 360–420 nm excitation wavelengths; and with a broad emission range of 360–600 nm. We have also shown that the CQDs were well internalized by muscle myoblasts (C2C12) and differentiated myotubes; the cell lines which have not been reported before.


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