Biventricular Morphology and Function Reference Values Derived From a Large Sample of Healthy Chinese Adults by Magnetic Resonance Imaging

Background: Quantification of cardiac structure and function is essential for diagnostic interpretation and clinical decision making. We sought to establish cardiovascular magnetic resonance (CMR) reference values of left and right ventricular (LV and RV) morphology and function based on a large sample of healthy Chinese adults.Methods: Five hundred fifty validated healthy Chinese adults (aged 21–70 years; 323 men) free of hypertension, diabetes, and obesity were included in this study. All the subjects were stratified by gender (men and women) and age decades. On cine CMR, measurements of biventricular end-diastolic, end-systolic, and stroke volumes (EDV, ESV, and SV), ejection fraction (EF), and end-diastolic LV wall thickness (LVWT) and mass (LVM) were obtained.Results: Men had greater LVEDV (111.6 ± 19.8 vs. 94.6 ± 15.6 ml), LVESV (36.5 ± 9.8 vs. 28.2 ± 7.9 ml), LVM (121.1 ± 19.9 vs. 86.1 ± 14.5 g), global end-diastolic LVWT (8.1 ± 1.1 vs. 6.7 ± 1.0 mm), RVEDV (128.0 ± 23.6 vs. 101.7 ± 17.0 ml), and RVESV (53.5 ± 13.7 vs. 36.8 ± 8.9 ml), while women had greater LVEF (67.5 ± 5.4 vs. 70.4 ± 5.7%) and RVEF (58.5 ± 5.2 vs. 64.0 ± 5.3%) (all p < 0.001). For both men and women, age was negatively correlated with LVEDV (r = −0.31 and r = −0.32), LVESV (r = −0.37 and r = −0.47), RVEDV (r = −0.31 and r = −0.29), and RVESV (r = −0.33 and r = −0.44), while it was positively correlated with LVEF (r = 0.28 and r = 0.43) and RVEF (r = 0.28 and r = 0.41) (all p < 0.001). Aging was associated with increasing global end-diastolic LVWT and LVM/LVEDV in both sexes (all p < 0.001). Older age was associated with increasing LVM only in women (r = 0.36, p < 0.001), not in men (r = 0.05, p = 0.359).Conclusions: We systematically provide age-, sex-, and body size-specific CMR reference values for biventricular morphology and function based on a large sample of healthy Chinese adults. Biventricular structure and function are significantly associated with age and sex.

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Reference Values of Left and Right Atrial Volumes and Phasic Function based on A Large Sample of Healthy Chinese Adults: A Cardiovascular Magnetic Resonance Study

10.21203/rs.3.rs-443718/v1 ◽

2021 ◽

Author(s):

Yiyuan Gao ◽

Zhen Zhang ◽

Shanshan Zhou ◽

Gengxiao Li ◽

Mingwu Lou ◽

...

Keyword(s):

Cardiovascular Magnetic Resonance ◽

Magnetic Resonance ◽

Reference Values ◽

Right Atrial ◽

Chinese Adults ◽

Large Sample ◽

Left And Right ◽

Healthy Chinese ◽

And Function ◽

Age And Sex

Abstract The left and right atrial (LA and RA) volumes and function are tightly linked to the morbidity and mortality of multiple cardiovascular diseases. We aimed to establish cardiovascular magnetic resonance (CMR) reference values for LA and RA volumes and phasic function based on a large sample of healthy Chinese adults. 408 validated healthy Chinese adults (54% men; aged 21–70 years) were included. The atrial volumes: maximum, minimum, and pre-atrial contraction (Vmax, Vmin, and Vpac); atrial phasic emptying fractions: total, passive, and booster (EF total, EF passive, and EF booster); atrial phasic emptying volumes: total, passive, and active (TEV, PEV, and AEV); and atrial expansion index (EI) were measured. Normal reference values were calculated and were stratified by sex (men and women) and age decades. The absolute LA and RA volumes and the indexed RA volumes were all greater in men. Women demonstrated higher LAEF total, LAEF booster, LAEI, RAEF total, RAEF passive, RAEF booster, and RAEI, while men had greater RATEV and RAAEV. Aging was positively correlated with the absolute and indexed LA and RA volumes, except for LA Vmax. LA and RA reservoir and conduit function including EF total, EI, EF passive, and PEV increased with age, while the atrial booster function (EF booster and AEV) decreased. We systematically provide age- and sex-specific CMR reference values for LA, RA volumes and phasic function based on a large sample of healthy Chinese adults with a wide age range. Both age and sex are closely associated with atrial volumes and function.

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Reference Values for Left Atrial Strain and Strain Rate Based on a Large Sample of Healthy Chinese Adults: An MR ‐Feature Tracking Study

Journal of Magnetic Resonance Imaging ◽

10.1002/jmri.27768 ◽

2021 ◽

Author(s):

Yiyuan Gao ◽

Zhen Zhang ◽

Gengxiao Li ◽

Shanshan Zhou ◽

Mingwu Lou ◽

...

Keyword(s):

Strain Rate ◽

Reference Values ◽

Left Atrial ◽

Feature Tracking ◽

Chinese Adults ◽

Left Atrial Strain ◽

Large Sample ◽

Strain And Strain Rate ◽

Healthy Chinese ◽

Atrial Strain

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Iodine availability, thyroid structure and function in residents of the city of Mirny, Republic of Sakha (Yakutia)

Problems of Endocrinology ◽

10.14341/probl200955623-25 ◽

2009 ◽

Vol 55 (6) ◽

pp. 23-25

Author(s):

V G Selyatitskaya ◽

M K Lel'kin ◽

I S Gerasimova ◽

Y V Lutov ◽

N A Pal'chikova ◽

...

Keyword(s):

Reference Values ◽

Thyroid Nodules ◽

Urinary Iodine ◽

Structure And Function ◽

Creatinine Ratio ◽

Men And Women ◽

Calculated Ratio ◽

And Function ◽

The City ◽

Serum Tsh

Iodine availability for residents of the city of Mirny, Republic of Sakha (Yakutia), was estimated from urinary iodine and creatinine levels and their calculated ratio. Median of iodine/creatinine ratio in the groups of children and adults included in the study was 167.2 and 110.5 mcg/g respectively. Goiter was diagnosed by ultrasound in 0.4% of men and 4.9% of women. Diffuse and focal changes of the thyroid echographic pattern were revealed in the overwhelming majority of the examined subjects (91.7% of the adults and 66.1% of the children). The frequency of thyroid nodules was 5.0% and 20.3% in men and women respectively. Serum TSH level exceeded the respective reference values in 10.9% of the men and 18.2% of the women.

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Editorial for “Reference Values for Left Atrial Strain and Strain Rate Based on a Large Sample of Healthy Chinese Adults: An MR‐Feature Tracking Study”

Journal of Magnetic Resonance Imaging ◽

10.1002/jmri.27821 ◽

2021 ◽

Author(s):

Yeon Hyeon Choe

Keyword(s):

Strain Rate ◽

Reference Values ◽

Left Atrial ◽

Feature Tracking ◽

Chinese Adults ◽

Left Atrial Strain ◽

Large Sample ◽

Strain And Strain Rate ◽

Healthy Chinese ◽

Atrial Strain

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Appropriate use criteria for cardiovascular magnetic resonance imaging (CMR): SIC—SIRM position paper part 1 (ischemic and congenital heart diseases, cardio-oncology, cardiac masses and heart transplant)

La radiologia medica ◽

10.1007/s11547-020-01332-6 ◽

2021 ◽

Vol 126 (3) ◽

pp. 365-379

Author(s):

Gianluca Pontone ◽

Ernesto Di Cesare ◽

Silvia Castelletti ◽

Francesco De Cobelli ◽

Manuel De Lazzari ◽

...

Keyword(s):

Heart Disease ◽

Magnetic Resonance ◽

Heart Transplant ◽

Congenital Heart ◽

Clinical Decision Making ◽

Heart Diseases ◽

Integrated Approach ◽

Clinical Decision ◽

Italian Society ◽

Cardiac Masses

AbstractCardiac magnetic resonance (CMR) has emerged as new mainstream technique for the evaluation of patients with cardiac diseases, providing unique information to support clinical decision-making. This document has been developed by a joined group of experts of the Italian Society of Cardiology and Italian society of Radiology and aims to produce an updated consensus statement about the current state of technology and clinical applications of CMR. The writing committee consisted of members and experts of both societies who worked jointly to develop a more integrated approach in the field of cardiac radiology. Part 1 of the document will cover ischemic heart disease, congenital heart disease, cardio-oncology, cardiac masses and heart transplant.

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