scholarly journals A Study on the Association Between Polymorphisms in the Cytochrome P450 Family 17 Subfamily A Member 1 Gene Region and Type 2 Diabetes Mellitus in Han Chinese

2018 ◽  
Vol 9 ◽  
Author(s):  
Long Wang ◽  
Yu-Ming Niu ◽  
Shi-Shi Wu ◽  
Chao Zhang ◽  
Li Zhou ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cytochrome P450 ◽  
Han Chinese ◽  
Gene Region ◽  
Cytochrome P450 Family

Glucagon gene polymorphism modifies the effects of smoking and physical activity on risk of type 2 diabetes mellitus in Han Chinese

Gene ◽  
2014 ◽  
Vol 534 (2) ◽  
pp. 352-355 ◽  
Author(s):  
Linlin Li ◽  
Kaiping Gao ◽  
Jingzhi Zhao ◽  
Tianping Feng ◽  
Lei Yin ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gene Polymorphism ◽  
Han Chinese

Association between insomnia and type 2 diabetes mellitus in Han Chinese individuals in Shandong Province, China

2018 ◽  
Vol 23 (1) ◽  
pp. 349-354 ◽  
Author(s):  
Yanhong Zhang ◽  
Yuanyuan Lin ◽  
Jianwu Zhang ◽  
Li Li ◽  
Xinxin Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Han Chinese ◽  
Shandong Province

scholarly journals Association of ADIPOQ variants with type 2 diabetes mellitus susceptibility in ethnic Han Chinese from northeast China

2016 ◽  
Vol 7 (6) ◽  
pp. 853-859 ◽  
Author(s):  
Meidong Yao ◽  
Yanhui Wu ◽  
Qingxiao Fang ◽  
Lulu Sun ◽  
Tingting Li ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Northeast China ◽  
Han Chinese

scholarly journals The rs1014290 Polymorphism of the SLC2A9 Gene Is Associated with Type 2 Diabetes Mellitus in Han Chinese

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Wan-Chun Liu ◽  
Chi-Chih Hung ◽  
Szu-Chia Chen ◽  
Ming-Yen Lin ◽  
Ling-I Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Glucose Transporter ◽  
Serum Glucose ◽  
Han Chinese ◽  
Nucleotide Polymorphisms ◽  
Type 2 Dm

Aims. TheSLC2A9gene encodes the glucose transporter 9, with the abilities of transporting both glucose and uric acid and is involved in the pancreatic glucose-stimulated insulin secretion. The single nucleotide polymorphisms (SNPs) ofSLC2A9accounted for 5% variance of serum uric acid (UA). UA was identified as a risk factor for type 2 diabetes mellitus (DM). We investigated whether theSLC2A9gene variations are associated with type 2 DM in Han Chinese.Methods. Three common SNPs of theSLC2A9, rs1014290, rs2280205, and rs3733591, were genotyped in 1003 Han Chinese randomly selected from Kaohsiung, Taiwan.Results. The variant SNP rs1014290 is associated with decreased 0.12-fold risk of type 2 DM (P=.002). Per-copy increase in the minor C-allele results in 0.13 mmol/L (P=.037) and 10.03 μmol/L (P=.016) decrease in serum glucose and UA, respectively.Conclusions. The SNP rs1014290 within theSLC2A9gene is associated with type 2 DM in Han Chinese.

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