scholarly journals Deducing the Impact of Physical Activity, Sedentary Behavior, and Physical Performance on Cognitive Function in Healthy Older Adults

2022 ◽  
Vol 13 ◽  
Author(s):  
Sina Gerten ◽  
Tobias Engeroff ◽  
Johannes Fleckenstein ◽  
Eszter Füzéki ◽  
Silke Matura ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Executive Function ◽  
Cognitive Function ◽  
Sedentary Behavior ◽  
Physical Performance ◽  
Peak Oxygen Uptake ◽  
Light Physical Activity ◽  
Healthy Older Adults ◽  
The Impact

Objectives: Participating in physical activity and maintaining physical performance as well as reducing sedentary behavior are discussed to be beneficially associated with cognitive function in older adults. The purpose of this cross-sectional analysis was to differentiate the relevance of objectively measured physical activity, physical performance, and sedentary behavior on cognitive function in healthy older adults (n = 56, age = 76 ± 7 yrs, gender = 30 female).Methods: Accelerometer based physical activity and sedentary behavior were analyzed as minutes per week spent sedentary and physically active with light or moderate to vigorous intensity. Participants' physical performance was assessed via cardiopulmonary exercise testing and analyzed as maximal workload and heart rate, heart rate reserve and peak oxygen uptake. The assessment of cognitive function included working memory, attention, executive function, and verbal memory. Data was analyzed with Spearman and partial correlations. Trial registration: NCT02343029.Results: Light physical activity was moderately associated with executive function (r = −0.339, p = 0.015). Attention was significantly associated with maximal workload (r = −0.286, p = 0.042) and peak oxygen uptake (r = −0.337, p = 0.015). Working memory was associated with maximal workload (r = 0.329, p = 0.017).Conclusion: Whereas a broad range of cognitive function were beneficially linked to physical performance, light intensity activities in particular showed an impact on executive function. Our research underlines the need to separate the impact of physical performance and physical activity on cognitive function and highlights the relevance of light physical activity.

The impact of acute exercise on cognitive function in healthy older adults

Physiotherapy ◽  
2015 ◽  
Vol 101 ◽  
pp. e402-e403
Author(s):  
J. Fortune ◽  
I. Robertson ◽  
A. Kelly ◽  
J. Hussey
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Acute Exercise ◽  
Healthy Older Adults ◽  
The Impact

Abstract MP01: Association of Objectively-measured Physical Activity with Cardiovascular Risk in Mobility-limited Older Adults

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Thomas W Buford ◽  
Don G Hire ◽  
Walter T Ambrosius ◽  
Stephen D Anton ◽  
Timothy S Church ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Sedentary Behavior ◽  
Risk Score ◽  
Activity Data ◽  
Mean Intensity ◽  
Wear Time ◽  
Low Intensity ◽  
Objectively Measured ◽  
The Impact

Introduction: In middle-aged adults, time spent being sedentary is associated with cardiovascular (CV) health risks independent of structured physical activity (PA). However, data are sparse regarding the impact of sedentary behavior on CV risk in older adults. The extent to which the absolute duration or intensity of daily PA reduces CV risk in older adults is also unknown. Objectives: Our objective was to examine the cross-sectional association between objectively-measured sedentary behavior and predicted CV risk among older adults in the Lifestyle Interventions and Independence for Elders (LIFE) study. The secondary objective was to evaluate associations between the duration/intensity of daily PA and predicted CV risk. Methods: LIFE is a randomized clinical trial to determine if regular PA prevents mobility disability among mobility-limited older adults. Activity data were collected by hip-worn accelerometer at baseline prior to participation in study interventions. Only participants with at least three days of accelerometry data (≥ 10 hrs wear time) were included. Unadjusted and adjusted linear regression was used to model the relationship between accelerometry measures and predicted 10-year Framingham risk of Hard Coronary Heart Disease (HCHD; i.e. myocardial infarction or coronary death). Adjusted models included demographic confounders (e.g. education, race, income) and health parameters (e.g. depression, cognition, arthritis) not in the risk score. Accelerometry cut-points were (in counts/min): sedentary behavior: < 100; low-intensity activity: 100-499; higher intensity activity: > 500. Results: Participants (n = 1170; 78.7 ± [SD] 5.3 years; 66.1% female) had a median HCHD risk of 10.3% (25 th -75 th %: 5.7-18.6). Over a mean accelerometer wear time of 8.1 ± 3.2 days, participants spent 77.0 ± 8.2% of their time sedentary. They also spent 16.6 ± 5.0% of their time in low-intensity PA and 6.4 ± 4.4% in higher-intensity PA. For all PA performed (> 100 counts/min), participants achieved a median of 393.4 (337.8-473.5) counts/min. In the unadjusted model, time spent sedentary (β = 2.41; 95% CI : 1.94, 2.89), in low-intensity PA (-2.56; -3.03, -2.08), and in higher-intensity PA (-1.60; -2.09, -1.11) were all associated with HCHD risk (all p’s < 0.001). These associations remained significant after adjustment. The mean intensity of daily PA was not significantly associated with HCHD risk in any model (p > 0.05). Conclusions: Daily time spent being sedentary is positively associated with predicted 10-year HCHD risk among mobility-limited older adults. Duration, but not mean intensity, of daily PA is inversely associated with HCHD risk score in this population.

Impact of Social Isolation on Physical Activity and Factors Associated With Sedentary Behavior in Older Adults During the COVID-19 Pandemic

2021 ◽  
pp. 1-5
Author(s):  
Giovana Z. Mazo ◽  
Felipe Fank ◽  
Pedro S. Franco ◽  
Bruna da Silva Vieira Capanema ◽  
Franciele da Silva Pereira
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Sedentary Behavior ◽  
Social Isolation ◽  
Low Income ◽  
Low Income Countries ◽  
Moderate Physical Activity ◽  
Cross Sectional ◽  
Factors Associated ◽  
The Impact

The objective was to analyze the impact of social isolation on moderate physical activity and factors associated with sedentary behavior of older adults during the COVID-19 pandemic. This was a cross-sectional study involving 111 older adults (aged 71.0 ± 6.87 years). The data were collected at two time points: in November 2019 and in June 2020. There was a decline in moderate physical activity when the minutes/week were compared before and during social isolation (p < .001). Sedentary behavior was associated with the condition of living alone. Older adults who lived alone were 3.29 times more likely to spend 4 hr or more in sedentary behavior than those who lived with a partner (95% confidence interval [1.01, 10.74]). Government agencies must establish PA-related health promotion strategies, especially in developing and low-income countries. Therefore, home exercises need to be encouraged to prevent the consequences of this pandemic period.

scholarly journals Blood Volume, Hemoglobin Mass, and Peak Oxygen Uptake in Older Adults: The Generation 100 Study

2021 ◽  
Vol 3 ◽  
Author(s):  
Kari Margrethe Lundgren ◽  
Nils Petter Aspvik ◽  
Knut Asbjørn Rise Langlo ◽  
Tonje Braaten ◽  
Ulrik Wisløff ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Oxygen Uptake ◽  
Blood Volume ◽  
Peak Oxygen Uptake ◽  
Healthy Older Adults ◽  
Erythrocyte Volume ◽  
Hemoglobin Mass ◽  
Older Men And Women ◽  
Rebreathing Method

Purpose: To investigate the association between blood volume, hemoglobin mass (Hbmass), and peak oxygen uptake (VO2peak) in healthy older adults.Methods: Fifty fit or unfit participants from the prospective randomized Generation 100 Study (n = 1,566) were included (age- and sex-specific VO2peak above or below average values). Blood, plasma, and erythrocyte volume and Hbmass were tested using the carbon monoxide rebreathing method within 1 week after VO2peak testing.Results: Mean age, BMI, Hbmass, blood volume, and VO2peak were 73.0 ± 2.1 years, 24.8 ± 3.3 kg·m2, 10.0 ± 1.7 g·kg−1, 76.4 ± 11.8 mL·kg−1, and 33.5 ± 8.4 mL·kg−1·min−1. VO2peak in fit and unfit participants and women and men were 38.6 ± 6.5 and 25.8 ± 3.8 mL·kg−1·min−1, 30.7 ± 7.6 mL·kg−1·min−1, and 35.5 ± 8.5 mL·kg−1·min−1, respectively. Women were shorter (Δ14 cm), leaner (Δ13 kg), and with less muscle mass (Δ9%) than men (P &lt; 0.05). Relative erythrocyte volume and Hbmass were lower in women, and blood and erythrocyte volume and Hbmass were higher in the fit participants (P &lt; 0.05). Hbmass and erythrocyte volume explained 40 and 37%, respectively, of the variability in VO2peak, with a limited effect of physical-activity adjustment (40 and 38%, respectively). Blood and plasma volume explained 15 and 25%, respectively, of VO2peak variability, and the association was strengthened adjusting for physical activity (25 and 31%, respectively), indicating a training-dependent adaptation in plasma but not erythrocyte volume (p ≤ 0.006).Conclusions: Blood and plasma volumes were moderately associated with VO2peak in healthy older men and women, and the association was strengthened after adjustment for physical activity. Hbmass and erythrocyte volume were strongly associated with VO2peak but unrelated to physical activity.

scholarly journals Verbal intelligence is a more robust cross-sectional measure of cognitive reserve than level of education in healthy older adults

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
R. Boyle ◽  
S. P. Knight ◽  
C. De Looze ◽  
D. Carey ◽  
S. Scarlett ◽  
...  
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Cognitive Function ◽  
Brain Structure ◽  
Cognitive Reserve ◽  
Cognitive Outcome ◽  
Verbal Intelligence ◽  
Cross Sectional ◽  
Healthy Older Adults ◽  
Occupational Complexity

Abstract Background Cognitive reserve is most commonly measured using socio-behavioural proxy variables. These variables are easy to collect, have a straightforward interpretation, and are widely associated with reduced risk of dementia and cognitive decline in epidemiological studies. However, the specific proxies vary across studies and have rarely been assessed in complete models of cognitive reserve (i.e. alongside both a measure of cognitive outcome and a measure of brain structure). Complete models can test independent associations between proxies and cognitive function in addition to the moderation effect of proxies on the brain-cognition relationship. Consequently, there is insufficient empirical evidence guiding the choice of proxy measures of cognitive reserve and poor comparability across studies. Method In a cross-sectional study, we assessed the validity of 5 common proxies (education, occupational complexity, verbal intelligence, leisure activities, and exercise) and all possible combinations of these proxies in 2 separate community-dwelling older adult cohorts: The Irish Longitudinal Study on Ageing (TILDA; N = 313, mean age = 68.9 years, range = 54–88) and the Cognitive Reserve/Reference Ability Neural Network Study (CR/RANN; N = 234, mean age = 64.49 years, range = 50–80). Fifteen models were created with 3 brain structure variables (grey matter volume, hippocampal volume, and mean cortical thickness) and 5 cognitive variables (verbal fluency, processing speed, executive function, episodic memory, and global cognition). Results No moderation effects were observed. There were robust positive associations with cognitive function, independent of brain structure, for 2 individual proxies (verbal intelligence and education) and 16 composites (i.e. combinations of proxies). Verbal intelligence was statistically significant in all models. Education was significant only in models with executive function as the cognitive outcome variable. Three robust composites were observed in more than two-thirds of brain-cognition models: the composites of (1) occupational complexity and verbal intelligence, (2) education and verbal intelligence, and (3) education, occupational complexity, and verbal intelligence. However, no composite had larger average effects nor was more robust than verbal intelligence alone. Conclusion These results support the use of verbal intelligence as a proxy measure of CR in cross-sectional studies of cognitively healthy older adults.

scholarly journals Verbal intelligence is a more robust cross-sectional measure of cognitive reserve than level of education in healthy older adults

2021 ◽  
Author(s):  
Rory Boyle ◽  
Silvin P Knight ◽  
Céline De Looze ◽  
Daniel Carey ◽  
Siobhan Scarlett ◽  
...  
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Cognitive Function ◽  
Brain Structure ◽  
Cognitive Reserve ◽  
Cognitive Outcome ◽  
Verbal Intelligence ◽  
Cross Sectional ◽  
Healthy Older Adults ◽  
Occupational Complexity

Abstract BackgroundCognitive reserve is most commonly measured using socio-behavioural proxy variables. These variables are easy to collect, have a straightforward interpretation, and are widely associated with reduced risk of dementia and cognitive decline in epidemiological studies. However, the specific proxies vary across studies and have rarely been assessed in complete models of cognitive reserve (i.e., alongside both a measure of cognitive outcome and a measure of brain structure). Complete models can test independent associations between proxies and cognitive function in addition to the moderation effect of proxies on the brain-cognition relationship. Consequently, there is insufficient empirical evidence guiding the choice of proxy measures of cognitive reserve and poor comparability across studies.MethodIn a cross-sectional study, we assessed the validity of 5 common proxies (education, occupational complexity, verbal intelligence, leisure activities, and exercise) and all possible combinations of these proxies in 2 separate community-dwelling older adult cohorts: The Irish Longitudinal Study on Ageing (TILDA; N = 313, mean age = 68.9 years, range = 54–88) and the Cognitive Reserve/Reference Ability Neural Network Study (CR/RANN; N = 234, mean age = 64.49 years, range = 50–80). 15 models were created with 3 brain structure variables (grey matter volume, hippocampal volume, and mean cortical thickness) and 5 cognitive variables (verbal fluency, processing speed, executive function, episodic memory, and global cognition).ResultsNo moderation effects were observed. There were robust positive associations with cognitive function, independent of brain structure, for 2 individual proxies (verbal intelligence and education), and 16 composites (i.e., combinations of proxies). Verbal intelligence was statistically significant in all models. Education was significant only in models with executive function as the cognitive outcome variable. Three robust composites were observed in more than two thirds of brain-cognition models: the composites of 1) occupational complexity and verbal intelligence, 2) education and verbal intelligence, and 3) education, occupational complexity and verbal intelligence. However, no composite had larger average effects nor was more robust than verbal intelligence alone.ConclusionThese results support the use of verbal intelligence as a proxy measure of CR in cross-sectional studies of cognitively healthy older adults.

scholarly journals Light Physical Activity Is Associated With Reduced Signs Of Immune Aging In Healthy Older Adults

2020 ◽  
Vol 52 (7S) ◽  
pp. 127-128
Author(s):  
Eunhan Cho ◽  
Bailey Theall ◽  
James Stampley ◽  
Brett Davis ◽  
Heather Quiriarte ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Light Physical Activity ◽  
Healthy Older Adults
Sign in / Sign up

Export Citation Format

Share Document