scholarly journals Load Auditory Feedback Boosts Crutch Usage in Subjects With Central Nervous System Lesions: A Pilot Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Federica Tamburella ◽  
Matteo Lorusso ◽  
Nevio Luigi Tagliamonte ◽  
Francesca Bentivoglio ◽  
Alessandra Bigioni ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Auditory Feedback ◽  
Gait Speed ◽  
Physical Therapist ◽  
Case Series ◽  
Experimental Session ◽  
Walking Aids ◽  
Single Experimental Session ◽  
10 Meter Walk Test

Background: Crutches are the most common walking aids prescribed to improve mobility in subjects with central nervous system (CNS) lesions. To increase adherence to the appropriate level of crutch usage, providing load-related auditory feedback (aFB) may be a useful approach. We sensorized forearm crutches and developed a custom software to provide aFB information to both user and physical therapist (PhT).Aim: Evaluate aFB effects on load control during gait by a self-controlled case series trial.Methods: A single experimental session was conducted enrolling 12 CNS lesioned participants. Load on crutch was recorded during 10 Meter Walk Test performed with and without aFB. In both cases, crutch load data, and gait speed were recorded. Usability and satisfaction questionnaires were administered to participants and PhTs involved.Results: Reliable data were obtained from eight participants. Results showed that compared to the no FB condition, aFB yielded a significant reduction in the mean load on the crutches during gait (p = 0.001). The FB did not influence gait speed or fatigue (p > 0.05). The experience questionnaire data indicated a positive experience regarding the use of aFB from both participants' and PhTs' perspectives.Conclusion: aFB significantly improves compliance with crutch use and does not affect gait speed or fatigue by improving the load placed on crutches. The FB is perceived by users as helpful, safe, and easy to learn, and does not interfere with attention or concentration while walking. Furthermore, the PhTs consider the system to be useful, easy to learn and reliable.

Adult primary central nervous system vasculitis. A case-series

2021 ◽  
Vol 429 ◽  
pp. 118840
Author(s):  
Silvio Piffer ◽  
Raffaella Tanel ◽  
Roberto Bortolotti ◽  
Umberto Rozzanigo ◽  
Bruno Giometto ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Series ◽  
Central Nervous System Vasculitis

scholarly journals Variable Presentations in Pulmonary Arteriovenous Malformation

2020 ◽  
Vol 8 (2) ◽  
pp. 1-8
Author(s):  
Nasir Ahmad Lone ◽  
Akshit Kumar ◽  
Waseem Ahmed Sheikh
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Clinical Symptoms ◽  
Case Series ◽  
Neurological Complications ◽  
Pulmonary Arteriovenous Malformations ◽  
Exertional Dyspnea ◽  
Paradoxical Emboli

Pulmonary arteriovenous malformations (PAVM) are a group of vascular anomalies of lung which present with variable clinical symptoms. Most patients with PAVM are asymptomatic but it can cause dyspnea on exertion, paradoxical emboli to brain causing various central nervous system complications like stroke and brain abscess, hemoptysis and rupture. The age at the presentation can range from 1st to 7th decade but the majority of patients present before the age of 30 years. PAVM is strongly associated with hereditary haemorrhagic telangiectasis which presents with epistaxis, mucocutaneous telangiectasias and AV malformations of various organs. In our case series, we have patients ranging from 3 yrs to 75 years with presentation ranging from asymptomatic to exertional dyspnea, hemoptysis and neurological complications.

scholarly journals Candida central nervous system infection after neurosurgery: a single-institution case series and literature review

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Hongwei Chen ◽  
Wenkai Cong ◽  
Dongcheng Xie ◽  
Shengjie Wang ◽  
Jianxing Niu ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Literature Review ◽  
Central Nervous System Infection ◽  
Case Series ◽  
Single Institution

scholarly journals OTHR-04. Gynecological Malignancies With Metastasis To The Central Nervous System: A Case Series and Systematic Review of the Literature

2021 ◽  
Vol 3 (Supplement_3) ◽  
pp. iii15-iii15
Author(s):  
Azeem Sajjad ◽  
Adeleso Adesina ◽  
Penelope Halkiadakis ◽  
Kelsey Murphy ◽  
Kathleen Mulligan ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Overall Survival ◽  
Nervous System ◽  
Literature Review ◽  
Metastatic Disease ◽  
Case Series ◽  
Progression Free Survival ◽  
Gynecologic Malignancies ◽  
Free Survival ◽  
Cns Metastasis

Abstract Introduction Gynecologic malignancies are an increasingly common proportion of central nervous system metastatic disease. As genetic sequencing technology improves and becomes more accessible, mutations associated with CNS metastasis are easier to elucidate. The aims of this case series and systematic literature review are to describe the patient population with CNS metastatic disease from a gynecologic primary, and to investigate why the proportion of CNS metastasis from gynecologic malignancies is increasing. Ultimately, we hope to improve understanding of this subset of metastatic CNS malignancies and improve management strategies. Methods A literature review of articles describing patients from 1990–2020 who were diagnosed with CNS metastasis from a known gynecologic primary malignancy was performed. Demographics, cancer type, mutation characteristics, management for metastatic disease, progression free survival, number of CNS metastases, and location of metastatic disease were assessed. Inclusion criteria were age>18 years, diagnosis of primary ovarian, uterine, or cervical cancer with confirmed metastatic disease to the CNS, including brain parenchyma, leptomeninges, or intradural spinal cord or dural metastases. Exclusion criteria included pediatric population and bony metastases (e.g., bony spine metastases without evidence of meningeal/parenchymal invasion). Results Our review showed that patients with gynecological metastasis to the CNS generally have worse outcomes regarding overall survival, progression free survival, and quality of life than patients without CNS metastasis. Discussion Our results infer that the reported increase in incidence of CNS metastasis from gynecologic malignancies is a reflection of improvement of detection given advances in technology, improved patient follow up, and increased overall survival of patients with gynecologic malignancies. Further characterization of mutations from gynecologic malignancies associated with brain metastasis could result in development of more treatment options for patients in the future and help determine factors that contribute to developing metastasis to the CNS of various degrees, thus, potentially inform treatment strategies.

Central Nervous System–Invading Eccrine Gland Carcinoma: A Clinicopathologic Case Series and Literature Review

2020 ◽  
Vol 138 ◽  
pp. e17-e25
Author(s):  
Saksham Gupta ◽  
Alexander F.C. Hulsbergen ◽  
David J. Segar ◽  
Blake M. Hauser ◽  
Joshua D. Bernstock ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Literature Review ◽  
Case Series ◽  
Eccrine Gland ◽  
Gland Carcinoma

Action observation therapy in pediatric patients with neuromotor deficits of the upper limbs secondary to central nervous system tumors

2019 ◽  
Vol 105 (6) ◽  
pp. NP75-NP78
Author(s):  
Marco Chisari ◽  
Raffaella Sensi ◽  
Carlo Alfredo Clerici ◽  
Fulvia Angela Gariboldi ◽  
Filippo Spreafico ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mirror Neurons ◽  
Action Observation ◽  
Case Series ◽  
Central Nervous System Tumor ◽  
Assessment Tests ◽  
System Tumor ◽  
Positive Results

This study reports a case series of patients with upper limb neuromotor deficits following pediatric central nervous system tumor and treated with rehabilitative therapy according to action observation therapy (AOT). AOT is based on the “mirror neurons” system and had positive results in various non-oncologic neurologic pathologies. This study is the first experience in the oncology field, and included 6 patients, 4 of whom were fully evaluated at 6-month follow-up. In all patients, therapy showed improvement in all assessment tests. These promising results lead to further studies to confirm their effectiveness.

scholarly journals Delirium in COVID-19: A case series and exploration of potential mechanisms for central nervous system involvement

2020 ◽  
Vol 65 ◽  
pp. 47-53 ◽  
Author(s):  
Scott R. Beach ◽  
Nathan C. Praschan ◽  
Charlotte Hogan ◽  
Samuel Dotson ◽  
Flannery Merideth ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Involvement ◽  
Case Series ◽  
System Involvement
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