scholarly journals COVID-19 and Traumatic Brain Injury (TBI); What We Can Learn From the Viral Pandemic to Better Understand the Biology of TBI, Improve Diagnostics and Develop Evidence-Based Treatments

2021 ◽  
Vol 12 ◽  
Author(s):  
Denes V. Agoston
2013 ◽  
Vol 14 (1) ◽  
pp. 42-50 ◽  
Author(s):  
Bridget B. Matarazzo ◽  
Hal S. Wortzel ◽  
Brooke A. Dorsey Holliman ◽  
Lisa A. Brenner

Traumatic brain injury (TBI) is prevalent among veterans and military personnel. These individuals present with increased rates of co-morbid mental health conditions and are at increased risk for suicide. Evidence-based treatments are needed to serve this population. A systematic review was conducted in order to determine the state of the science with respect to interventions aimed at improving mental health outcomes among veterans and military personnel. Results indicate that only three published articles exist that met inclusion criteria for this systematic review. All three study designs were observational in nature. Significant risk of bias was noted. The body of evidence was rated according to the GRADE approach. Although the published work marks an important starting point in evaluating evidence-based treatments for veterans and military personnel with TBI, the overall quality of evidence was determined to be very low. Implications for both future research and current practice are discussed.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A314-A315
Author(s):  
Bridget Cotner ◽  
Risa Nakase-Richardson ◽  
Becky Gius ◽  
Lauren Fournier ◽  
Alexa Watach ◽  
...  

Abstract Introduction Obstructive Sleep Apnea (OSA) is prevalent after moderate to severe traumatic brain injury (TBI) and may diminish recovery when left untreated. Despite the demonstrated importance of treating OSA following TBI, assessment for OSA during or soon after inpatient rehabilitation for TBI is limited. Little is known about barriers to implementing OSA screening and early diagnosis during inpatient rehabilitation thus hindering the translation of evidence-based OSA assessment procedures into clinical practice and potentially delaying necessary OSA treatment. The current analysis explored facilitators and barriers to implementing OSA screening tools in an inpatient rehabilitation setting from the perspectives of end user stakeholders. Methods Patients, families, industry, clinical providers and administrators participated in a two-day meeting following completion of a diagnostic clinical trial of OSA screening and diagnostic tools during inpatient rehabilitation. Stakeholders were provided with open ended questions generated by study investigators and given the opportunity to respond on paper or a “graffiti wall” (i.e., white board). Example questions include “What are the greatest needs of the healthcare system related to sleep apnea and TBI?” and “What are the key things we need to consider to move results into real-world practice?” Qualitative content analyses using a rapid matrix approach were conducted from stakeholder feedback obtained during the two-day meeting, which included a guided review of emerging OSA research and discussion of potential implementation barriers of OSA assessment during inpatient rehabilitation. Results Improved screening and treatment practices for OSA were the greatest needs identified. To meet these needs, stakeholders identified the importance of improving patient, family, and staff understanding of OSA (e.g., health literacy) and other sleep disorders through education; inpatient rehabilitation access to resources (technology; sleep providers); and reimbursement for additional inpatient procedures. Conclusion Although treatment of OSA is crucial for recovery during inpatient rehabilitation following TBI, barriers to earlier recognition, diagnosis, and treatment of OSA exists across several different domains, including education, resources, and funding policies. Findings support future implementation efforts to translate evidence-based care into practice to improve patient outcomes. Support (if any) PCORI-NCT03033901


2019 ◽  
Vol 9 (3) ◽  
pp. 241-249 ◽  
Author(s):  
Barbara Weissman ◽  
Madeline Joseph ◽  
Gary Gronseth ◽  
Kelly Sarmiento ◽  
Christopher C. Giza

Purpose of reviewIn September 2018, the Centers for Disease Control and Prevention (CDC) published an evidence-based guideline on the diagnosis and management of mild traumatic brain injury (mTBI) among children.Recent findingsBased on a systematic review of the evidence that covers research published over a 25-year span (1990–2015), the CDC Pediatric mTBI Guideline strives to optimize the care of pediatric patients with mTBI. The guideline was developed using a rigorous methodology developed by the American Academy of Neurology.SummaryClinical practice recommendations in the CDC Pediatric mTBI Guideline can help guide neurologists with critical diagnostic and management decisions and to implement evidence-based strategies for the recovery of their young patients with this injury.


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