scholarly journals Prognostic Relevance of 18F-FDG-PET/CT-Guided Target Volume Delineation in Loco-Regionally Advanced Nasopharyngeal Carcinomas: A Comparative Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Ouying Yan ◽  
Hui Wang ◽  
Yaqian Han ◽  
Shengnan Fu ◽  
Yanzhu Chen ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Tumor Volume ◽  
Study Groups ◽  
Target Volume ◽  
Dose Painting ◽  
Ct Guided ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct

IntroductionAn optimal approach to define tumor volume in locoregionally advanced nasopharyngeal carcinoma (NPC) using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) remains unclear. This retrospective study aimed at comparing the outcomes and toxicities of different FDG-PET/CT-guided techniques for primary tumor volume delineation in locoregionally advanced NPC.MethodsFrom August 2015 to February 2018, 292 patients with stage III-IVB NPC received FDG-PET/CT-guided IMRT. Three PET/CT-based techniques were used to determine the gross tumor volume (GTV) as follows: visual criteria (group A; n = 98), a standard uptake value (SUV) threshold of 2.5 (group B; n = 95), and a threshold of 50% maximal intensity (group C, n = 99) combined with a dose-painting technique.ResultsIn groups A, B, and C, the 5-year LRFS rates were 89.4%, 90.0%, and 97.8%, respectively (p = 0.043). The 5-year DMFS rates were 75.1%, 76.0%, and 87.7%, respectively (p = 0.043). The 5-year DFS rates were 70.9%, 70.3%, and 82.2%, respectively (p = 0.048). The 5-year OS rates were 73.5%, 73.9%, and 84.9%, respectively (p = 0.038). Group C showed significantly higher 5-year LRFS, LRRFS, DMFS, DFS, and OS than those in groups A and B (p < 0.05). No statistically significant differences were observed between the three study groups in the cumulative incidences of grade 3-4 acute and late toxicities. Multivariate analyses showed that the PET/CT-guided technique for target volume delineation was an independent prognostic factor for 5-year LRFS, DFS, DMFS, and OS (p = 0.039, p = 0.030, p = 0.035 and p = 0.028, respectively), and was marginally significant in predicting LRRFS (p = 0.080).ConclusionsThe 50% SUVmax threshold regimen for GTV delineation with dose-painting appeared to be superior to the visual criteria or SUV2.5 threshold in locoregionally advanced NPC, and there was no increased toxicity.

FDG-PET/CT Imaging for Staging and Target Volume Delineation in Preoperative Conformal Radiotherapy of Rectal Cancer

2008 ◽  
Vol 70 (5) ◽  
pp. 1423-1426 ◽  
Author(s):  
Maria Chiara Bassi ◽  
Lucia Turri ◽  
Gianmauro Sacchetti ◽  
Gianfranco Loi ◽  
Barbara Cannillo ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Fdg Pet ◽  
Conformal Radiotherapy ◽  
Target Volume ◽  
Ct Imaging ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct

Respiratory gated [18F]FDG PET/CT for target volume delineation in stereotactic radiation treatment of liver metastases

2012 ◽  
Vol 188 (7) ◽  
pp. 592-598 ◽  
Author(s):  
R.A. Bundschuh ◽  
N. Andratschke ◽  
J. Dinges ◽  
M.N. Duma ◽  
S.T. Astner ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Fdg Pet ◽  
Radiation Treatment ◽  
Target Volume ◽  
Target Volume Delineation ◽  
Stereotactic Radiation ◽  
Volume Delineation ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

926 poster AN ADAPTIVE THRESHOLD ALGORITHM FOR FDG-PET/CT TARGET VOLUME DELINEATION: VALIDATION IN LYMPHNODES.

2011 ◽  
Vol 99 ◽  
pp. S355
Author(s):  
L. Vigna ◽  
L. Deantonio ◽  
R. Matheoud ◽  
G. Sacchetti ◽  
G. Loi ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Target Volume ◽  
Adaptive Threshold ◽  
Target Volume Delineation ◽  
Threshold Algorithm ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Impact of 18F-FDG PET/CT on target volume delineation in recurrent or residual gynaecologic carcinoma

2012 ◽  
Vol 7 (1) ◽  
Author(s):  
Hansjörg Vees ◽  
Nathalie Casanova ◽  
Thomas Zilli ◽  
Hestia Imperiano ◽  
Osman Ratib ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Target Volume ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

1163 poster FDG-PET/CT FOR TARGET VOLUME DELINEATION IN THE VOLUMETRIC MODULATED ARC RADIOTHERAPY IN CERVICAL CANCER

2011 ◽  
Vol 99 ◽  
pp. S432-S433
Author(s):  
R. Lazzari ◽  
A. Cecconi ◽  
V. Dell'Acqua ◽  
A. Vavassori ◽  
L.L. Travaini ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Fdg Pet ◽  
Target Volume ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct ◽  
Volumetric Modulated Arc Radiotherapy

scholarly journals FDG-PET/CT and MR imaging for target volume delineation in rectal cancer radiotherapy treatment planning: a systematic review

2021 ◽  
pp. 1-11
Author(s):  
Elizabeth E. Olanloye ◽  
Aarthi Ramlaul ◽  
Atara I. Ntekim ◽  
Segun S. Adeyemi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
Fdg Pet ◽  
Target Volume ◽  
Resonance Imaging ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct

Abstract Aim: The aim of this systematic review was to synthesise and summarise evidence surrounding the clinical use of fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) and magnetic resonance imaging (MRI) for target volume delineation (TVD) in rectal cancer radiotherapy planning. Methods: PubMed, EMBASE, Cochrane library, CINAHL, Web of Science and Scopus databases and other sources were systematically queried using keywords and relevant synonyms. Eligible full-text studies were assessed for methodological quality using the QUADAS-2 tool. Results: Eight of the 1448 studies identified met the inclusion criteria. Findings showed that MRI significantly delineate larger tumour volumes (TVs) than FDG-PET/CT while diffusion-weighted magnetic resonance imaging (DW-MRI) defined smaller gross tumour volumes (GTVs) compared to T2 weighted-Magnetic Resonance Image. CT-based GTVs were found to be larger compared to FDG-PET/CT. FDG-PET/CT also identified new lesions in 15–17% patients and TVs extending outside the routinely used clinical standard CT TV in 29–83% patients. Between observers, delineated volumes were similar and consistent between MRI sequences, whereas interobserver agreement was significantly improved with FDG-PET/CT than CT. Conclusion: FDG-PET/CT and DW-MRI appear to delineate smaller rectal TVs and show improved interobserver variability. Overall, this study provides valuable insights into the amount of attention in the research literature that has been paid to imaging for TVD in rectal cancer.

O26. A review on target volume delineation using FDG-PET/CT images for radiation oncology

2016 ◽  
Vol 32 ◽  
pp. 149
Author(s):  
M. du Toit ◽  
A. Potgieter ◽  
M. Heunis ◽  
R. Boellaard ◽  
J. Pruim
Keyword(s):  
Radiation Oncology ◽  
Fdg Pet ◽  
Target Volume ◽  
Ct Images ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct
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