scholarly journals Re-evaluating Renal Angina Index: An Authentic, Evidence-Based Instrument for Acute Kidney Injury Assessment: Critical Appraisal

2021 ◽  
Vol 9 ◽  
Author(s):  
Rupesh Raina ◽  
Sidharth Kumar Sethi ◽  
Isabelle Mawby ◽  
Nikhil Datla ◽  
Nikhita Kumar ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Literature Search ◽  
Adult Population ◽  
Kidney Injury ◽  
Predictive Ability ◽  
Pediatric Populations ◽  
Injury Assessment ◽  
Renal Angina Index ◽  
Renal Angina ◽  
Accurate Indicator

Background/Introduction: Renal angina index (RAI) used to calculate and accurately predict risk for the development of acute kidney injury (AKI) has been heavily explored. AKI is traditionally diagnosed by an increase in serum creatinine (SCr) concentration or oliguria, both of which are neither specific nor sensitive, especially among children. An RAI score may be calculated by combining objective signs of kidney dysfunction (such as SCr) and patient context, such as AKI risk factors, thus potentially serving as a more accurate indicator for AKI.Objective: Due to the propitious and novel nature of RAI, this editorial commentary aims to analyze the current literature on RAI and determine how well RAI serves as a predictor of AKI outcomes.Method: A comprehensive literature search was conducted in PubMed/Medline and Google Scholar between January 2012 and July 2020. Literature included the prognostic aspect of early prediction of AKI in the pediatric and adult population via RAI.Results: The initial literature search included 149 studies, and a total of 10 studies reporting the outcomes of interest were included. The overall sample size across these studies was 11,026. The predictive ability of RAI had a pooled (95% CI) sensitivity of 79.21%, specificity of 73.22%, and negative predictive value of 94.83%.Conclusion: RAI shows benefit in the prediction of AKI among adult and pediatric populations. However, there is a lack of sufficient data, and further prospective studies are needed in pediatric populations to use RAI as a principal AKI indicator among clinicians.

scholarly journals Urinary NGAL incorporation into Renal Angina Index for early detection of acute kidney injury in critically ill children

2019 ◽  
Vol 3 (2) ◽  
pp. 093-099 ◽  
Author(s):  
Ali Mohammed Abu Zeid ◽  
Doaa Youssef Mohammed* ◽  
Amal Saeed AbdAlazeem ◽  
Anas Saad Elsayed Mohammed Seddeeq ◽  
Ashraf Mohamed Elnaany
Keyword(s):  
Acute Kidney Injury ◽  
Early Detection ◽  
Critically Ill ◽  
Kidney Injury ◽  
Critically Ill Children ◽  
Urinary Ngal ◽  
Renal Angina Index ◽  
Renal Angina

Diagnostic accuracy of renal angina index alone or in combination with biomarkers for predicting acute kidney injury in children

2022 ◽  
Author(s):  
Jitendra Meena ◽  
Jogender Kumar ◽  
Christy Cathreen Thomas ◽  
Lesa Dawman ◽  
Karalanglin Tiewsoh ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Diagnostic Accuracy ◽  
Kidney Injury ◽  
Renal Angina Index ◽  
Renal Angina

Relationship Between Renal Angina Index and D-Dimer Improvement Towards Acute Kidney Injury in Covid-19 Patients in Special Isolation Room of Dr. Soetomo Hospital Surabaya

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Fadhil Rasyid ◽  
Bambang Pujo Semedi ◽  
Arie Utariani ◽  
Teuku Aswin
Keyword(s):  
Acute Kidney Injury ◽  
Serum Creatinine ◽  
Kidney Injury ◽  
World Health ◽  
Isolation Room ◽  
Injury Criteria ◽  
Health Organization ◽  
Renal Angina Index ◽  
Renal Angina ◽  
D Dimer

Since the World Health Organization (WHO) declared COVID-19 as pandemic in March 2020, the number of new case findings in Indonesia has continued to increase. As happened in the city of Surabaya. Even in severe cases deterioration is rapid and progressive. One of them is the high D-dimer level in COVID-19 patients, which indicates the presence of vascular thrombosis, resulting in organ failure syndromes such as Acute Kidney Injury (AKI). Such conditions clearly indicate that this virus attacks the kidneys. It is known that the prevalence of AKI is 17%, where 77% of AKI patients experienced severe COVID-19 infection, and 52% died. For this reason, this study was prepared with the aim of knowing the relationship between increased levels of D-Dimer Renal Angine Index and the incidence of Acute Kidney Injury (AKI) in COVID-19 patients in the Special Isolation Room of Dr. Soetomo Hospital Surabaya. This study was a retrospective cohort analytic observational study with a sample size of 30. The Acute Kidney Injury criteria in this study used an increase in serum creatinine ≥ 0.3 mg / dL within 48 hours, or an increase in serum creatinine ≥ 1.5 times. Through research conducted, it is known that the Renal Angina Index can be used to predict the incidence of AKI in this study with p <0.0001 and sensitivity 71%, specificity 21% (r: 0.43; strong CC> 0.3) with a limit of 7. It can be concluded that there is a relationship which is significant between the Renal Angina Index on the incidence of Acute Kidney Injury (AKI). However, there was no significant relationship between increased D-Dimer levels and the incidence of acute kidney injury.

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