scholarly journals The Adverse Effects of Prenatal METH Exposure on the Offspring: A Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Jia-Hao Li ◽  
Jia-Li Liu ◽  
Kai-Kai Zhang ◽  
Li-Jian Chen ◽  
Jing-Tao Xu ◽  
...  
Keyword(s):  
Public Health ◽  
Adverse Effects ◽  
Gut Microbiota ◽  
Multiple Organ ◽  
Health Issue ◽  
Public Health Issue ◽  
Placental Barrier ◽  
Cardiovascular Toxicity ◽  
Exposure During Pregnancy ◽  
Abuse During Pregnancy

Abuse of methamphetamine (METH), an illicit psychostimulant, is a growing public health issue. METH abuse during pregnancy is on the rise due to its stimulant, anorectic, and hallucinogenic properties. METH can lead to multiple organ toxicity in adults, including neurotoxicity, cardiovascular toxicity, and hepatotoxicity. It can also cross the placental barrier and have long-lasting effects on the fetus. This review summarizes neurotoxicity, cardiovascular toxicity, hepatotoxicity, toxicity in other organs, and biomonitoring of prenatal METH exposure, as well as the possible emergence of sensitization associated with METH. We proposed the importance of gut microbiota in studying prenatal METH exposure. There is rising evidence of the adverse effects of METH exposure during pregnancy, which are of significant concern.

Identifying changes in trends in the age standardized incidence of melanoma in Australia

2019 ◽  
Vol 3 (4) ◽  
pp. 250-252 ◽  
Author(s):  
David M Hille
Keyword(s):  
Public Health ◽  
Linear Regression ◽  
Iterative Process ◽  
Linear Trend ◽  
Piecewise Linear ◽  
Health Issue ◽  
Public Health Issue ◽  
Piecewise Linear Regression ◽  
Significant Public Health ◽  
Males And Females

ObjectiveTo identify changes in the linear trend of the age-standardized incidence of melanoma in Australia for all persons, males, and females. MethodsA two-piece piecewise linear regression was fitted to the data. The piecewise breakpoint varied through an iterative process to determine the model that best fits the data.ResultsStatistically significant changes in the trendof the age-standardized incidence of melanoma in Australia were found for all persons, males, and females. The optimal breakpoint for all persons and males was at 1998. For females, the optimal breakpoint was at 2005. The trend after these breakpoints was flatter than prior to the breakpoints, but still positive.ConclusionMelanoma is a significant public health issue in Australia. Overall incidence continues to increase. However, the rate at which the incidence is increasing appears to be decreasing.

The Other View of Disposable Diapers

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 350-351
Author(s):  
ROBERT L. CAMPBELL
Keyword(s):  
Public Health ◽  
Solid Wastes ◽  
Health Hazards ◽  
The Other ◽  
Health Issue ◽  
Public Health Issue ◽  
Public Health Hazards ◽  
Disposable Diapers

To The Editor.— I'm writing to you to express my extreme disappointment at the publication of the commentary titled "Baby Bottoms and Environmental Conundrums: Disposable Diapers and the Pediatrician" that appeared in the August 1991 issue of Pediatrics.1 Public Health Issue About Diaper Disposal. The authors have treated briefly the issue of public health and diaper disposal.1,p387 The reader is left with a perception that discarded diapers pose public health hazards. While the issue of public health and the disposal of diapers and other solid wastes is important, it is treated neither adequately nor fairly in this commentary.

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