scholarly journals Human Umbilical Cord Mesenchymal Stem Cell Differentiation Into Odontoblast-Like Cells and Endothelial Cells: A Potential Cell Source for Dental Pulp Tissue Engineering

2020 ◽  
Vol 11 ◽  
Author(s):  
Shuang Zhang ◽  
Weiwei Zhang ◽  
Yanping Li ◽  
Liping Ren ◽  
Haotian Deng ◽  
...  
2011 ◽  
Vol 23 (3) ◽  
pp. 325-332 ◽  
Author(s):  
V.T. Sakai ◽  
M.M. Cordeiro ◽  
Z. Dong ◽  
Z. Zhang ◽  
B.D. Zeitlin ◽  
...  

Multipotency is a defining characteristic of post-natal stem cells. The human dental pulp contains a small subpopulation of stem cells that exhibit multipotency, as demonstrated by their ability to differentiate into odontoblasts, neural cells, and vascular endothelial cells. These discoveries highlight the fundamental role of stem cells in the biology of the dental pulp and suggest that these cells are uniquely suited for dental pulp tissue-engineering purposes. The availability of experimental approaches specifically designed for studies of the differentiation potential of dental pulp stem cells has played an important role in these discoveries. The objective of this review is to describe the development and characterization of the Tooth Slice/Scaffold Model of Dental Pulp Tissue Engineering. In addition, we discuss the multipotency of dental pulp stem cells, focusing on the differentiation of these cells into functional odontoblasts and into vascular endothelial cells.


2018 ◽  
Vol 14 (5) ◽  
pp. 668-676 ◽  
Author(s):  
Tomoatsu Kaneko ◽  
Bin Gu ◽  
Phyo Pyai Sone ◽  
Su Yee Myo Zaw ◽  
Hiroki Murano ◽  
...  

Odontology ◽  
2016 ◽  
Vol 105 (4) ◽  
pp. 392-397 ◽  
Author(s):  
Takafumi Ito ◽  
Tomoatsu Kaneko ◽  
Yukiko Sueyama ◽  
Reika Kaneko ◽  
Takashi Okiji

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