Computational Intelligence Model of Orally Disintegrating Tablets: An Attempt to Explain Disintegration Process

2021 ◽  
Vol 11 (1) ◽  
pp. 24
Author(s):  
Jakub Szlęk ◽  
Adam Pacławski ◽  
Natalia Czub ◽  
Aleksander Mendyk

We obtained a curated database based on the database published elsewhere. Chemical descriptors were introduced as characteristics of active pharmaceutical ingredients (APIs). We used H2O AutoML platform in order to develop a Deep Learning model and SHAP method to explain its predictions. Obtained results were satisfactory with NRMSE of 8.1% and R2 of 0.84. Finally, we identified critical parameters affecting the process of disintegration of directly compressed ODTs.

2020 ◽  
Vol 13 (4) ◽  
pp. 627-640 ◽  
Author(s):  
Avinash Chandra Pandey ◽  
Dharmveer Singh Rajpoot

Background: Sentiment analysis is a contextual mining of text which determines viewpoint of users with respect to some sentimental topics commonly present at social networking websites. Twitter is one of the social sites where people express their opinion about any topic in the form of tweets. These tweets can be examined using various sentiment classification methods to find the opinion of users. Traditional sentiment analysis methods use manually extracted features for opinion classification. The manual feature extraction process is a complicated task since it requires predefined sentiment lexicons. On the other hand, deep learning methods automatically extract relevant features from data hence; they provide better performance and richer representation competency than the traditional methods. Objective: The main aim of this paper is to enhance the sentiment classification accuracy and to reduce the computational cost. Method: To achieve the objective, a hybrid deep learning model, based on convolution neural network and bi-directional long-short term memory neural network has been introduced. Results: The proposed sentiment classification method achieves the highest accuracy for the most of the datasets. Further, from the statistical analysis efficacy of the proposed method has been validated. Conclusion: Sentiment classification accuracy can be improved by creating veracious hybrid models. Moreover, performance can also be enhanced by tuning the hyper parameters of deep leaning models.


2021 ◽  
Vol 296 ◽  
pp. 126564
Author(s):  
Md Alamgir Hossain ◽  
Ripon K. Chakrabortty ◽  
Sondoss Elsawah ◽  
Michael J. Ryan

Sign in / Sign up

Export Citation Format

Share Document