scholarly journals Towards Non-Invasive Extraction and Determination of Blood Glucose Levels

2017 ◽  
Vol 4 (4) ◽  
pp. 82 ◽  
Author(s):  
Catherine Todd ◽  
Paola Salvetti ◽  
Katy Naylor ◽  
Mohammad Albatat
Author(s):  
Mohsen Askarbioki ◽  
Mojtaba Mortazavi ◽  
Abdolhamid Amooee ◽  
Saeid Kargar ◽  
Mohammad Afkhami-Ardekani ◽  
...  

Objective: Today, there are various non-invasive techniques available for the determination of blood glucose levels. In this study, the level of blood glucose was determined by developing a new device using near-infrared (NIR) wavelength, glass optical waveguide, and the phenomenon of evanescent waves. Materials and Methods: The body's interstitial fluid has made possible the development of new technology to measure the blood glucose. As a result of contacting the fingertip with the body of the borehole rod, where electromagnetic waves are reflected inside, evanescent waves penetrate from the borehole into the skin and are absorbed by the interstitial fluid. The electromagnetic wave rate absorption at the end of the borehole rod is investigated using a detection photodetector, and its relationship to the people's actual blood glucose level. Following precise optimization and design of the glucose monitoring device, a statistical population of 100 participants with a maximum blood glucose concentration of 200 mg/dL was chosen. Before measurements, participants put their index finger for 30 seconds on the device. Results: According to this experimental study, the values measured by the innovative device with Clark grid analysis were clinically acceptable in scales A and B. The Adjusted Coefficient of Determination of the data was estimated to be 0.9064. Conclusion: For future investigations, researchers are recommended to work with a larger statistical population and use error reduction trends to improve the accuracy and expand the range of measurements.


2021 ◽  
Vol 5 (1) ◽  
pp. 14-25
Author(s):  
Nurul Fadhilah ◽  
Erfiani Erfiani ◽  
Indahwati Indahwati

The calibration method is an alternative method that can be used to analyze the relationship between invasive and non-invasive blood glucose levels. Calibration modeling generally has a large dimension and contains multicolinearities because usually in functional data the number of independent variables (p) is greater than the number of observations (p>n). Both problems can be overcome using Functional Regression (FR) and Functional Principal Component Regression (FPCR). FPCR is based on Principal Component Analysis (PCA). In FPCR, the data is transformed using a polynomial basis before data reduction. This research tried to model the equations of spectral calibration of voltage value excreted by non-invasive blood glucose level monitoring devices to predict blood glucose using FR and FPCR. This study aimed to determine the best calibration model for measuring non-invasive blood glucose levels with the FR and FPCR. The results of this research showed that the FR model had a bigger coefficient determination (R2) value and lower Root Mean Square Error (RMSE) and Root Mean Square Error Prediction (RMSEP) value than the FPCR model, which was 12.9%, 5.417, and 5.727 respectively. Overall, the calibration modeling with the FR model is the best model for estimate blood glucose level compared to the FPCR model.


Sensors ◽  
2021 ◽  
Vol 21 (20) ◽  
pp. 6820
Author(s):  
Bushra Alsunaidi ◽  
Murad Althobaiti ◽  
Mahbubunnabi Tamal ◽  
Waleed Albaker ◽  
Ibraheem Al-Naib

The prevalence of diabetes is increasing globally. More than 690 million cases of diabetes are expected worldwide by 2045. Continuous blood glucose monitoring is essential to control the disease and avoid long-term complications. Diabetics suffer on a daily basis with the traditional glucose monitors currently in use, which are invasive, painful, and cost-intensive. Therefore, the demand for non-invasive, painless, economical, and reliable approaches to monitor glucose levels is increasing. Since the last decades, many glucose sensing technologies have been developed. Researchers and scientists have been working on the enhancement of these technologies to achieve better results. This paper provides an updated review of some of the pioneering non-invasive optical techniques for monitoring blood glucose levels that have been proposed in the last six years, including a summary of state-of-the-art error analysis and validation techniques.


2015 ◽  
Vol 8 (2) ◽  
pp. 1244-1260 ◽  
Author(s):  
Anand Thati ◽  
Arunangshu Biswas ◽  
Shubhajit Roy Chowdhury ◽  
Tapan Kumar Sau

2019 ◽  
Vol 10 (1) ◽  
pp. 133-138 ◽  
Author(s):  
Jan-Hugo Andersen ◽  
Olav Bjerke ◽  
Fatos Blakaj ◽  
Vilde Moe Flugsrud ◽  
Fredrik Alstad Jacobsen ◽  
...  

Abstract Sixteen volunteers each drank 700 ml sugar-containing soft drink during two successive periods and the blood sugar was measured at 10 min intervals together with electrical impedance spectroscopy and near infrared spectroscopy (NIR). A maximum correlation of 0.46 was found for the electrical measurements but no clear separation between low and high blood glucose levels were found in the NIR measurements. The latter was attributed to the experimental design where the NIR probe was removed from the skin between each measurement.


1986 ◽  
Vol 67 (6) ◽  
pp. 436-438
Author(s):  
A. A. Kamaeva ◽  
M. V. Sukhanova ◽  
A. L. Braunagel ◽  
A. Ya. Kozhevnikova ◽  
S. S. Khaletova

The aim of this work was to study the urinary excretion of adrenaline and noradrenaline, blood glucose content and determination of skin temperature of students at different stages of the educational process. The simultaneous study of these indicators, in our opinion, is justified on the basis of biochemical effects of catecholamines-stimulation of glycogenolysis and lipolysis, increase in blood glucose levels, as well as its further use by tissues for energy needs.


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