scholarly journals Cancer and Pregnancy: A Comprehensive Review

Cancers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 3048
Author(s):  
Roxana Schwab ◽  
Katharina Anic ◽  
Annette Hasenburg

Cancer diagnosis and treatment in pregnant women is a challenging situation. A multidisciplinary network of specialists is required to guide both, the expecting mother and the unborn child through the diagnostic workup and the cytotoxic therapy, by balancing the respective risks and benefits. Tumor entity, stage, biology and gestational week at diagnosis determine the appropriate approach. As premature delivery emerged as one of the main risk factors for adverse long-term outcome of the progeny, it should be avoided, if reasonable from the oncological perspective. This article offers a comprehensive review with respect to the various aspects of cancer in pregnancy.

Author(s):  
Christian Singer

SummaryThis year’s ASCO Annual Meeting has been a showcase for the overwhelming success of novel, targeted therapies, particularly in a tumor entity that has – until recently – been felt to be only treatable with chemotherapy. New data are extremely encouraging, but also highlight the need for target identification beyond the classical clinicopathological factors. Both, the Olympia and the Neotala study have been performed in BRCA-mutated tumors, and their results clearly point to the necessity to offer germline testing to HER2-negative high risk early breast cancer. In addition, GeparNuevo once more highlights the fact that immunotherapy is here to stay, not only in the advanced breast cancer setting, but also in early stage breast cancer. The side effect profile is acceptable, and long-term outcome a real improvement to conventional chemotherapy.


2001 ◽  
Vol 120 (5) ◽  
pp. A624-A624 ◽  
Author(s):  
J ARTS ◽  
M ZEEGERS ◽  
G DHAENS ◽  
G VANASSCHE ◽  
M HIELE ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 490-490
Author(s):  
Stefan Zastrow ◽  
Sven Oehlschläger ◽  
Oliver W. Hakenberg ◽  
Steffen Leike ◽  
Manfred P. Wirth

2006 ◽  
Vol 175 (4S) ◽  
pp. 420-421
Author(s):  
Gemma Viola Fantini ◽  
Andrew Nisbet ◽  
Pejman Mortarjem ◽  
Claudia Panzer ◽  
Ricardo Munarriz

2004 ◽  
Vol 171 (4S) ◽  
pp. 81-81
Author(s):  
Michael Cohen ◽  
Bernard H. Bochner ◽  
Harry W. Herr

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