scholarly journals Skeletal Muscle Depletion and Major Postoperative Complications in Locally-Advanced Head and Neck Cancer: A Comparison between Ultrasound of Rectus Femoris Muscle and Neck Cross-Sectional Imaging

Cancers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 347
Author(s):  
Andrea Galli ◽  
Michele Colombo ◽  
Carmine Prizio ◽  
Giulia Carrara ◽  
Francesca Lira Lira Luce ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Rectus Femoris ◽  
Cross Sectional ◽  
Major Complications ◽  
Cross Sectional Imaging ◽  
Sectional Imaging ◽  
Rectus Femoris Muscle

Skeletal muscle mass (SMM) depletion has been validated in many surgical fields as independent predictor of complications through cross-sectional imaging. We evaluated SMM depletion in a stage III-IV head and neck cancer cohort, comparing the accuracy of CT/MRI at C3 level with ultrasound (US) of rectus femoris muscle (RF) in terms of prediction of major complications. Patients submitted to surgery were recruited from 2016 to 2021. SMM was estimated on CT/MRI by calculating the sum of the cross-sectional area (CSA) of the sternocleidomastoid and paravertebral muscles at C3 level and its height-indexed value (cervical skeletal muscle index, CSMI) and on US by computing the CSA of RF. Specific thresholds were defined for both US and CT/MRI according to ROC curve in terms of best prediction of 30-day major complications to detect sarcopenic subjects (40–53%). Sixty-five patients completed the study. At univariate analysis, major complications were associated to lower RF CSA, lower CSA at C3 level and lower CSMI, together with previous radiotherapy, higher ASA score and higher modified frailty index (mFI). At multivariate analysis RF CSA (OR 7.07, p = 0.004), CSA at C3 level (OR 6.74, p = 0.005) and CSMI (OR 4.02, p = 0.025) were confirmed as independent predictors in three different models including radiotherapy, ASA score and mFI. This analysis proved the value of SMM depletion as predictor of major complications in a head and neck cancer cohort, either defined on cross-sectional imaging at C3 or on US of RF.

Comparison between anatomical cross-sectional imaging and 18F-FDG PET/CT in the staging, restaging, treatment response, and long-term surveillance of squamous cell head and neck cancer

2014 ◽  
Vol 35 (2) ◽  
pp. 123-134 ◽  
Author(s):  
Laura Evangelista ◽  
Anna Rita Cervino ◽  
Sotirios Chondrogiannis ◽  
Maria Cristina Marzola ◽  
Anna Margherita Maffione ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Fdg Pet ◽  
Cross Sectional ◽  
Pet Ct ◽  
Cross Sectional Imaging ◽  
18F Fdg ◽  
Sectional Imaging ◽  
Fdg Pet Ct

scholarly journals Imaging in head and neck cancer: United Kingdom National Multidisciplinary Guidelines

2016 ◽  
Vol 130 (S2) ◽  
pp. S28-S31 ◽  
Author(s):  
H Lewis-Jones ◽  
S Colley ◽  
D Gibson
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Residual Disease ◽  
Ct Imaging ◽  
Cross Sectional ◽  
Positron Emission ◽  
Pet Ct ◽  
Cross Sectional Imaging ◽  
The Uk

AbstractThis guideline is endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. This paper summarises the current imaging modalities in use for head and neck cancer evaluation. It highlights their role in the management with recommendations on modality choice for each cancer subsite.Recommendations• Offer appropriate radiological imaging, based on tumour extent, site and local expertise, to stage tumours and plan treatment for patients diagnosed with head and neck cancer. (G)• Consider positron emission tomography combined with computed tomography (PET–CT) imaging if conventional cross-sectional imaging identifies no primary site. (R)• Offer PET–CT imaging 12 weeks after non-surgical treatment to detect residual disease. (R)

scholarly journals Masticatory muscle index for indicating skeletal muscle mass in patients with head and neck cancer

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251455
Author(s):  
Sheng-Wei Chang ◽  
Yuan-Hsiung Tsai ◽  
Cheng-Ming Hsu ◽  
Ethan I. Huang ◽  
Geng-He Chang ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Characteristic Curve ◽  
Lumbar Vertebra ◽  
Ct Images ◽  
Ct Scans ◽  
Cross Sectional ◽  
Skeletal Muscle Index

Background A typical assessment for sarcopenia involves the use of abdominal computed tomography (CT) for calculating the skeletal muscle index (SMI) at the level of the third lumbar vertebra (L3). However, abdominal CT is not regularly performed on patients with head and neck cancer (HNC). We investigated whether masticatory SMI (M-SMI) measurements based on head and neck CT scans can be used to conduct sarcopenia assessments by evaluating whether M-SMI is correlated with L3-SMI. Methods Abdominal and head and neck CT images of patients with trauma (n = 50) and HNC (n = 52) were analyzed retrospectively. Both manual delineation and threshold selection methods were used to measure cross-sectional areas of masticatory muscles and those of muscles at the L3 level on CT images. Muscle cross-sectional areas were normalized to height squared to calculate SMI, and a multivariate linear regression model was established to evaluate the correlation between the M-SMI and L3-SMI. Receiver operating characteristic curve analysis was used to assess the ability of the M-SMI to identify sarcopenia, and Cox logistic regression was used to identify predictors of sarcopenia. Results Patients with HNC had significantly lower M-SMI and L3-SMI than did patients with trauma (p = 0.011 and 0.03, respectively). M-SMI and L3-SMI were strongly correlated (r = 0.901, p < 0.001); in the multivariate model that included sex, the correlation was stronger (r = 0.913, p < 0.001). The associations of sarcopenia with a lower M-SMI (p < 0.001), male sex (p = 0.028), and advanced age (p = 0.011) were significant, and multivariate logistic analysis demonstrated that an M-SMI of <5.5 was an independent predictor of sarcopenia (hazard ratio = 5.37, p < 0.001). Conclusions M-SMI assessment in routine head and neck CT scans is feasible and can be an alternative for detecting sarcopenia in patients with HNC.

Clinical utility of a functional lumen imaging probe in management of dysphagia following head and neck cancer therapies

Endoscopy ◽  
2017 ◽  
Vol 49 (09) ◽  
pp. 848-854 ◽  
Author(s):  
Peter Wu ◽  
Michal Szczesniak ◽  
Julia Maclean ◽  
Lennart Choo ◽  
Harry Quon ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Diagnostic Accuracy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Characteristic Curve ◽  
Diagnostic Tools ◽  
Cross Sectional ◽  
Imaging Probe ◽  
Functional Lumen Imaging Probe ◽  
Dysphagic Patients

Abstract Background and aims Chemoradiotherapy for head and neck cancer (HNC) with/without laryngectomy commonly causes dysphagia. Pharyngoesophageal junction (PEJ) stricturing is an important contributor. We aimed to validate a functional lumen imaging probe (the EndoFLIP system) as a tool for quantitating pretreatment PEJ distensibility and treatment-related changes in HNC survivors with dysphagia and to evaluate the diagnostic accuracy of EndoFLIP-derived distensibility in detecting PEJ strictures. Methods We studied 34 consecutive HNC survivors with long-term (> 12 months) dysphagia who underwent endoscopic dilation for suspected strictures. Twenty non-dysphagic patients undergoing routine endoscopy served as controls. PEJ distensibility was measured at endoscopy with the EndoFLIP system pre- and post-dilation. PEJ stricture was defined as the presence of a mucosal tear post-dilation. Results PEJ stricture was confirmed in 22/34 HNC patients (65 %). During distension up to 60 mmHg, the mean EndoFLIP-derived narrowest cross-sectional area (nCSA) in HNC patients with strictures, without strictures, and in controls were 58 mm2 (95 % confidence interval [CI] 22 to 118), 195 mm2 (95 %CI 129 to 334), and 227 mm2 (95 %CI 168 to 316), respectively. A cutoff of 114 mm2 for the nCSA at the PEJ had perfect diagnostic accuracy in detecting strictures (area under the receiver operating characteristic curve = 1). In patients with strictures, a single session of dilation increased the nCSA by 29 mm2 (95 %CI 20 to 37; P < 0.001). In patients with no strictures, dilation caused no change in the nCSA (mean difference 13 mm2 [95 %CI −4 to 30]; P = 0.13). Conclusions EndoFLIP is a highly accurate technique for the detection of PEJ strictures. EndoFLIP may complement conventional diagnostic tools in the detection of pharyngeal outflow obstruction.

Patterns of stress coping and depression among patients with head and neck cancer: A Japanese cross-sectional study

2017 ◽  
Vol 27 (2) ◽  
pp. 556-562 ◽  
Author(s):  
Kanako Ichikura ◽  
Aya Yamashita ◽  
Taro Sugimoto ◽  
Seiji Kishimoto ◽  
Eisuke Matsushima
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Cross Sectional Study ◽  
Stress Coping ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Giovanni Marasco ◽  
Sinan Sadalla ◽  
Giulio Vara ◽  
Rita Golfieri ◽  
Davide Festi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Liver Disease ◽  
Liver Failure ◽  
Chronic Liver Disease ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Failure ◽  
Cross Sectional ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

Sarcopenia is gaining attention as a negative prognostic factor in different fields of medicine, including chronic liver failure. However, the assessment of sarcopenia in patients with liver diseases is often neglected due to unawareness of reliable tools and methods and thus is limited to research studies. Cross-sectional imaging is a diffuse diagnostic tool and is commonly performed in patients with chronic liver failure. The last advancements in radiology image analysis using dedicated software allow an easy and standardized method to assess skeletal muscle volume. Several measures can be obtained from cross-sectional imaging analysis to evaluate sarcopenia in patients affected by chronic liver disease. We aimed to review the recent advances in imaging-based sarcopenia assessment, in particular in patients with chronic liver diseases. As a result, we found that the skeletal muscle index (SMI) seems to be a reliable method to assess sarcopenia in cirrhotic patients. Even if further studies are needed to validate proper cut-offs for each clinical endpoint, physicians are invited to consider the assessment of sarcopenia in the work-up of patients with chronic liver disease.

Head and Neck Cancer Literacy in Nigeria: A systematic Review of the Literature

2021 ◽  
Vol 1 (1) ◽  
pp. 25-49
Author(s):  
Kehinde Kanmodi ◽  
Precious Kanmodi ◽  
Mike Ogbeide ◽  
Jacob Nwafor
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
African Country ◽  
Cross Sectional ◽  
Level Of Knowledge ◽  
Cancer Literacy ◽  
English Articles ◽  
Study Quality Assessment ◽  
Appraisal Tool

Abstract Introduction: Head and neck cancer (HNC), oral cancer inclusive (OC), is one of the major causes of cancer-related deaths globally, especially in Nigeria – a developing African country. Public literacy about HNC plays a very crucial role in HNC prevention. Aim: This study aimed to systematically review existing literature on literacy of HNC in Nigeria. Methods: We searched the PubMed, Google Scholar and AJOL databases for all relevant English articles published on HNC literacy in Nigeria from January 2000 till October 2020. Only relevant articles were included for the study. Quality assessment of the full text of the included articles was done using the Appraisal Tool for Cross-Sectional Studies (AXIS); also, relevant data were extracted from these articles and analyzed thematically. Results: A total of 21 articles (19 surveys and 2 interventional studies), which studied a total population of 7,883 people, were included in the study. All the included articles were rated “excellent” (70 – 100%), regarding quality. The awareness rates of HNC/OC, as documented in the included studies, ranged from 0% to 100%; however, the rate recorded in the majority of these studies was <50%. In-depth knowledge of HNC/OC was found to be generally poor among the surveyed population groups; however, education intervention was found to improve in-depth knowledge of HNC and attitudes toward peer and nonpeer education about HNC among Nigerians. Conclusion: The level of knowledge regarding HNC, in Nigeria, is low. The use of relevant health education programs to boost knowledge about HNC among the Nigerian public is highly recommended.

Radiology of acute mastoiditis and its complications: a pictorial review and interpretation checklist

2019 ◽  
Vol 133 (10) ◽  
pp. 856-861
Author(s):  
M W Mather ◽  
P D Yates ◽  
J Powell ◽  
I Zammit-Maempel
Keyword(s):  
Head And Neck ◽  
Surgical Planning ◽  
Systematic Approach ◽  
Acute Mastoiditis ◽  
Cross Sectional ◽  
Imaging Technology ◽  
Radiological Features ◽  
Pictorial Review ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

AbstractBackgroundMastoiditis is an otological emergency, and cross-sectional imaging has a role in the diagnosis of complications and surgical planning. Advances in imaging technology are becoming increasingly sophisticated and, by the same token, the ability to accurately interpret findings is essential.MethodsThis paper reviews common and rare complications of mastoiditis using case-led examples. A radiologist-derived systematic checklist is proposed, to assist the ENT surgeon with interpreting cross-sectional imaging in emergency mastoiditis cases when the opinion of a head and neck radiologist may be difficult to obtain.ResultsA 16-point checklist (the ‘mastoid 16’) was used on a case-led basis to review the radiological features of both common and rare complications of mastoiditis; this is complemented with imaging examples.ConclusionAcute mastoiditis has a range of serious complications that may be amenable to treatment, once diagnosed using appropriate imaging. The proposed checklist provides a systematic approach to identifying complications of mastoiditis.

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