scholarly journals Intradural Pediatric Spinal Tumors: An Overview from Imaging to Novel Molecular Findings

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1710
Author(s):  
Antonio Marrazzo ◽  
Antonella Cacchione ◽  
Sabrina Rossi ◽  
Alessia Carboni ◽  
Carlo Gandolfo ◽  
...  

Pediatric spinal tumors are rare and account for 10% of all central nervous system tumors in children. Onset usually occurs with chronic nonspecific symptoms and may depend on the intra- or extradural neoplastic location. Meningiomas, schwannomas, and neurofibromas are the most common intradural-extramedullary lesions, while astrocytomas and ependymomas represent the majority of intramedullary tumors. The new molecular discoveries regarding pediatric spinal cancer currently contribute to the diagnostic and therapeutic processes. Moreover, some familial genetic syndromes can be associated with the development of spinal tumors. Currently, magnetic resonance imaging (MRI) is the standard reference for the evaluation of pediatric spinal tumors. Our aim in this review was to describe the imaging of the most frequent intradural intra/extramedullary pediatric spinal tumors and to investigate the latest molecular findings and genetic syndromes.

2006 ◽  
Vol 17 (2) ◽  
pp. 89-106 ◽  
Author(s):  
Marco Essig ◽  
Marc-Andr?? Weber ◽  
Hendrik von Tengg-Kobligk ◽  
Michael V. Knopp ◽  
William T.C. Yuh ◽  
...  

Radiology ◽  
1985 ◽  
Vol 155 (1) ◽  
pp. 131-136 ◽  
Author(s):  
W Kucharczyk ◽  
M Brant-Zawadzki ◽  
D Sobel ◽  
M B Edwards ◽  
W M Kelly ◽  
...  

2018 ◽  
Vol 52 (1) ◽  
pp. 34-35
Author(s):  
Manish Modi ◽  
Vivek Lal ◽  
Aditya Choudhary ◽  
Manoj Goyal ◽  
Chirag K Ahuja ◽  
...  

ABSTRACT Introduction Yellow-colored cerebrospinal fluid (CSF) suggestive of xanthochromia can be due to elevated CSF protein and can be one of the causes of papilledema. Observation We observed a 55-year-old lady with papilledema with yellow-colored CSF which was hypercoagulable along with elevated CSF protein and no cells. Her systemic and nervous system examination was unremarkable except for the eye findings. Her contrast-enhanced brain magnetic resonance imaging (MRI) showed multiple meningiomas, and on imaging of the spine, she had multiple contrast-enchancing intradural, extramedullary lesions. Her eye findings were attributed to Froin syndrome found in patients with spinal tumors. Conclusion Our case stresses the need to keep the possibility of Froin syndrome in mind while evaluating patients with papilledema and it may be pertinent to perform a spinal imaging, especially when no apparent cause for papilledema is found. How to cite this article Choudhary A, Goyal MK, Modi M, Mukherjee KK, Ahuja CK, Lal V. Froin Syndrome. J Postgrad Med Edu Res 2018;52(1):34-35.


Children ◽  
2020 ◽  
Vol 7 (11) ◽  
pp. 210
Author(s):  
Renata Barbosa Paolilo ◽  
Kumaran Deiva ◽  
Rinze Neuteboom ◽  
Kevin Rostásy ◽  
Ming Lim

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated central nervous system (CNS) disorder, characterized by polyfocal symptoms, encephalopathy and typical magnetic resonance imaging (MRI) findings, that especially affects young children. Advances in understanding CNS neuroimmune disorders as well as the association of myelin oligodendrocyte glycoprotein antibody (MOG-Ab) with both monophasic and recurrent forms of ADEM have led to new insights into its definition, management and outcome. In this review, we aim to provide an update based on current epidemiologic, clinical, radiological and immunopathological aspects and clinical outcome of ADEM.


Radiographics ◽  
2017 ◽  
Vol 37 (1) ◽  
pp. 258-280 ◽  
Author(s):  
Charmi Vijapura ◽  
Ehab Saad Aldin ◽  
Aristides A. Capizzano ◽  
Bruno Policeni ◽  
Yutaka Sato ◽  
...  

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