Structure Characterization of Polysaccharide from Chinese Yam (Dioscorea opposite Thunb.) and Its Growth-Promoting Effects on Streptococcus thermophilus

To clarify the mechanisms underlying the growth-promoting effects of yam polysaccharide on Streptococcus thermophilus (S. thermophilus), the yam polysaccharide was extracted using a deep eutectic solvents (DESs) method and separated into four fractions by DEAE-cellulose 52. These fractions were used as the alternative carbon source to substitute lactose to compare their growth-promoting effects on S. thermophilus. Furthermore, their molecular weight, monosaccharide and functional groups’ composition, microscopic forms and other basic structure characterizations were analyzed. The results showed that all the fractions could significantly promote S. thermophilus growth, and fractions exhibited significantly different growth-promoting effects, whose viable count increased by 6.14, 6.03, 11.48 and 11.29%, respectively, relative to those in the M17 broth medium. Structure-activity relationship analysis revealed that the high growth-promoting activity of yam polysaccharide might be more dependent on the higher molecular weight, the higher galacturonic acid content and its complex spatial configuration, and the existence of β-glycosides would make the yam polysaccharide have a better growth-promoting effect on S. thermophilus.

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Antioxidant activity of yeast mannans and their growth-promoting effect on Lactobacillus strains

Food & Function ◽

10.1039/d1fo01470f ◽

2021 ◽

Author(s):

Yong Wang ◽

Chongyu Shen ◽

Kai Huo ◽

Di Cai ◽

Guoqun Zhao

Keyword(s):

Molecular Weight ◽

Antioxidant Activity ◽

Promoting Effect ◽

Growth Promoting ◽

Different Molecular Weight

Different molecular-weight yeast mannans from S. cerevisiae were prepared and their antioxidant activity was evaluated.

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Prognostic significance of mmp-1, mmp-3, and mthfr genetic polymorphism for evaluation of uterine leiomyoma and adenomyosis progression

Journal of obstetrics and women s diseases ◽

10.17816/jowd83482 ◽

2005 ◽

Vol 54 (3) ◽

pp. 55-59

Author(s):

Е. В. Morozova ◽

А. B. Chukhlovin ◽

N. V. Kulagina ◽

А. А. Totolian

Keyword(s):

Uterine Leiomyoma ◽

Clinical Course ◽

Prognostic Significance ◽

High Growth ◽

Protective Role ◽

Promoting Effect ◽

Matrix Metalloproteinase 1 ◽

Growth Promoting ◽

Low Incidence

Carriage of hyperactive alleles of matrix metalloproteinase-1 (MMP-1) gene is associated with enhanced growth of various neoplasias in humans. When studying the frequency of promoter variants of MMP -1 and -3 genes in 170 patients with uterine leiomyoma, significant associations were revealed between low incidence of MMP-1 1G/1G genotype, high growth rates of leiomyoma, multifocal growth and more common adenomyosis development, thus presuming a protective role of MMP-1/1G homozygosity in the development of symptomatic myoma and adenomyosis and growth-promoting effect of the 2G allele. Hence, the promoter genotype of MMP-1 may be considered as possible genetic marker to predict clinical course of the uterine leiomyoma.

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Xyloglucan- and cello-oligosaccharides: Antagonists of the growth-promoting effect of H+

Physiologia Plantarum ◽

10.1034/j.1399-3054.1990.800117.x ◽

1990 ◽

Vol 80 (1) ◽

pp. 109-113 ◽

Cited By ~ 2

Author(s):

Ester P. Lorences ◽

Gordon J. McDougall ◽

Stephen C. Fry

Keyword(s):

Promoting Effect ◽

Growth Promoting

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IS THE GROWTH-PROMOTING EFFECT OF ANTIBIOTICS CONNECTED WITH THYROID FUNCTION?

Acta Endocrinologica ◽

10.1530/acta.0.0160365 ◽

1954 ◽

Vol 16 (4) ◽

pp. 365-368 ◽

Cited By ~ 4

Author(s):

Antti Telkkä ◽

A. N. Kuusisto

Keyword(s):

Thyroid Function ◽

Promoting Effect ◽

Growth Promoting

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Quantitative Relationship between Stimulus and Response in the Growth-Promoting Effect of Spirometra mansonoides Spargana on the Hypophysectomized Rat

Journal of Parasitology ◽

10.2307/3277738 ◽

1970 ◽

Vol 56 (4) ◽

pp. 840 ◽

Cited By ~ 8

Author(s):

Justus F. Mueller

Keyword(s):

Quantitative Relationship ◽

Promoting Effect ◽

Growth Promoting

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Effects of follicular fluids on the growth of porcine preantral follicle and oocyte

Zygote ◽

10.1017/s0967199408004711 ◽

2008 ◽

Vol 16 (3) ◽

pp. 239-247 ◽

Cited By ~ 8

Author(s):

T. Metoki ◽

H. Iwata ◽

M. Itoh ◽

M. Kasai ◽

A. Takajyo ◽

...

Keyword(s):

Calf Serum ◽

Follicle Development ◽

Preantral Follicle ◽

Promoting Effect ◽

Oocyte Growth ◽

Preantral Follicles ◽

Molecular Weights ◽

Heat Treated ◽

Growth Promoting ◽

Follicular Fluids

SummaryWe examined the effect of supplementing the culture medium with follicular fluid (FF) on the growth of porcine preantral follicles and oocytes. Firstly, preantral follicles were retrieved from ovaries and then FF was collected from all antral follicles that were 2–7 mm in diameter (AFF), which included large follicles of 4–7 mm in diameter (LFF) and small follicles of 2–3 mm in diameter (SFF). When preantral follicles with a diameter of 250 μm were cultured in medium containing AFF, the growth of follicles and oocytes was greater than when follicles were cultured in medium containing fetal calf serum (FCS). When this growth-promoting effect in AFF was compared for LFF and SFF, the LFF were shown to be significantly more effective than SFF. This LFF effect was lost, however, when the concentration of LFF in the medium was decreased from 5% to 0.5% or when LFF were heat treated (60 °C for 30 min) or trypsin was added. In contrast, a decrease in SFF concentration from 5% to 0.5% and heat treatment of the SFF enhanced preantral follicle growth. Furthermore, proteins obtained from LFF that had molecular weights greater than 10 kDa (LFF > 10 kDa) had similar, but relatively reduced, growth-promoting properties. The remaining three LFF protein fractions (<10 kDa or <100 kDa or >100 kDa), however, did not have these growth-promoting properties. In conclusion, the supplementation of medium with LFF, rather than serum, enhanced preantral follicle and oocyte growth. Factors that enhanced follicle development in LFF and factors that suppressed follicle development in SFF were proteins and these LFF factors ranged in size from 10 kDa to over 100 kDa.

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