scholarly journals The Effect of Rice vs. Wheat Ingestion on Postprandial Gastroesophageal Reflux (GER) Symptoms in Patients with Overlapping GERD-Irritable Bowel Syndrome (IBS)

Foods ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 26
Author(s):  
Tanisa Patcharatrakul ◽  
Sittikorn Linlawan ◽  
Suppawatsa Plaidum ◽  
Sutep Gonlachanvit
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gastroesophageal Reflux ◽  
Area Under The Curve ◽  
Gas Production ◽  
Intestinal Gas ◽  
Ch4 Concentration ◽  
Irritable Bowel ◽  
Gerd Symptoms ◽  
Randomized Crossover Study ◽  
Gut Fermentation

A randomized crossover study in twenty-one patients (18F, age 50 ± 13 years) with overlapping GERD-IBS was conducted to evaluate the effects of rice noodles (low FODMAPs) vs. wheat noodles (high FODMAPs) on typical GER symptoms, and the correlation between GERD symptoms and intestinal gas production. Results: Heartburn and regurgitation scores were highest in most patients (19/21) during the first 15 min after meals. At 15 min after lunch, wheat was significantly associated with more regurgitation and heartburn than rice. Also, at 15 min after breakfast, wheat aggravated more regurgitation than rice. Wheat ingestion was significantly associated with higher H2 and CH4 levels after lunch compared to rice, whereas gas levels before lunch were similar (p > 0.05). The area under the curve of H2 and CH4 concentration 15 min after a lunch of wheat moderately correlated with the regurgitation severity at 15-min (r = 0.56, p < 0.05). Conclusion: Wheat induced more GERD symptoms than rice in patients with overlapping GERD-IBS. This effect, immediately developed after lunch, was associated with more intestinal gas production. Thus, a low FODMAPs diet may relieve postprandial GERD symptoms in GERD patients with overlapping IBS. Wheat inducing more regurgitation than rice after breakfast suggests other mechanism(s) besides gut fermentation.

scholarly journals Effect of Rice, Wheat, and Mung Bean Ingestion on Intestinal Gas Production and Postprandial Gastrointestinal Symptoms in Non-Constipation Irritable Bowel Syndrome Patients

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2061 ◽  
Author(s):  
Sittikorn Linlawan ◽  
Tanisa Patcharatrakul ◽  
Nicha Somlaw ◽  
Sutep Gonlachanvit
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mung Bean ◽  
Statistical Significance ◽  
Gastrointestinal Symptoms ◽  
Gas Production ◽  
Intestinal Gas ◽  
Gi Symptoms ◽  
Ch4 Concentration ◽  
Irritable Bowel

The aim of this study is to evaluate the effect of rice, mung bean, and wheat noodle ingestion on intestinal gas production and postprandial gastrointestinal (GI) symptoms in non-constipation irritable bowel syndrome (IBS) patients. Methods: Twenty patients (13 F, 46 ± 11 y) underwent 8 h breath test studies and GI symptom evaluations after standard rice, wheat, or mung bean noodle meals at 8:00 a.m. in a randomized crossover study with a 1-week washout period. The same meal was ingested at 12:00 p.m. Results: The H2 and CH4 concentration in the breath samples were similar at baseline (rice:wheat:mung bean, H2 = 3.6 ± 0.5:4.1 ± 0.5:4.0 ± 0.7 ppm, CH4 = 1.3 ± 0.3:2.1 ± 0.4:1.9 ± 0.4 ppm, p > 0.05). Beginning at the fifth hour after breakfast, H2 and CH4 concentrations significantly increased after wheat compared to rice and mung bean (8 h AUC H2 = 4120 ± 2622:2267 ± 1780:2356 ± 1722, AUC CH4 = 1617 ± 1127:946 ± 664:943 ± 584 ppm-min, respectively) (p < 0.05). Bloating and satiety scores significantly increased after wheat compared to rice (p < 0.05), and increased but did not reach statistical significance compared to mung bean (p > 0.05). A higher bloating score after wheat compared to rice and mung bean was observed clearly after lunch but not after breakfast. Conclusion: Wheat ingestion produced more intestinal gas and more bloating and satiety scores compared to rice and mung bean, especially after lunch. This provides insight into the role of intestinal gas in the development of bloating symptoms in IBS.

scholarly journals Clinical Management of the Microbiome in Irritable Bowel Syndrome

2020 ◽  
Author(s):  
Christopher N Andrews ◽  
Sacha Sidani ◽  
John K Marshall
Keyword(s):  
Irritable Bowel Syndrome ◽  
Barrier Function ◽  
Intestinal Barrier ◽  
Management Plan ◽  
Gas Production ◽  
Intestinal Barrier Function ◽  
Pathophysiological Mechanism ◽  
Intestinal Gas ◽  
Gi Transit ◽  
Irritable Bowel

Abstract Background A growing body of evidence suggests that dysbiosis contributes to the onset and symptomatology of irritable bowel syndrome (IBS) and other functional bowel disorders. Changes to the gastrointestinal microbiome may contribute to the underlying pathophysiology of IBS. Methods The present review summarizes the potential effects of microbiome changes on GI transit, intestinal barrier function, immune dysregulation and inflammation, gut–brain interactions and neuropsychiatric function. Results A multimodal approach to IBS management is recommended in accordance with current Canadian guidelines. Pharmacologic treatments are advised to target the presumed underlying pathophysiological mechanism, such as dysregulation of GI transit, peristalsis, intestinal barrier function and pain signalling. The management plan for IBS may also include treatments directed at dysbiosis, including dietary modification and use of probiotics, which may promote the growth of beneficial bacteria, affect intestinal gas production and modulate the immune response; and the administration of periodic short courses of a nonsystemic antibiotic such as rifaximin, which may re-establish microbiota diversity and improve IBS symptoms. Conclusion Dysregulated host–microbiome interactions are complex and the use of microbiome-directed therapies will necessarily be empiric in individual patients. A management algorithm comprising microbiome- and nonmicrobiome-directed therapies is proposed.

Manipulation of dietary short chain carbohydrates alters the pattern of gas production and genesis of symptoms in irritable bowel syndrome

2010 ◽  
Vol 25 (8) ◽  
pp. 1366-1373 ◽  
Author(s):  
Derrick K Ong ◽  
Shaylyn B Mitchell ◽  
Jacqueline S Barrett ◽  
Sue J Shepherd ◽  
Peter M Irving ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gas Production ◽  
Short Chain ◽  
Irritable Bowel

Combined detection of inorganic syndromes of the gastrointestinal tract and their differential diagnosis.

2021 ◽  
Vol 2021 (2) ◽  
pp. 68-71
Author(s):  
R.I. Khalafova ◽  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Differential Diagnosis ◽  
Gastrointestinal Tract ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Functional Dyspepsia ◽  
Military Personnel ◽  
Reflux Disease ◽  
Irritable Bowel ◽  
Combined Detection

To study the frequency of detection of combinations of the main syndromes of the gastrointestinal tract (GIT) and their differential diagnosis, consisting of irritable bowel syndrome (IBS), syndrome of functional dyspepsia (SFD), chronic idiopathic dyspepsia (CIT) and gastroesophageal reflux disease (GERD). The main gastrointestinal syndromes are quite often detected among different groups of military personnel and members of their families. ES plays an important role in their formation. International recommendations allow anamnestic diagnosis of each of the syndromes in separately and in combination with each other. The medical appealability of patients depends on the severity of the symptoms of the syndromes, it is most pronounced when they are combined.

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