The Effect of Rice vs. Wheat Ingestion on Postprandial Gastroesophageal Reflux (GER) Symptoms in Patients with Overlapping GERD-Irritable Bowel Syndrome (IBS)

A randomized crossover study in twenty-one patients (18F, age 50 ± 13 years) with overlapping GERD-IBS was conducted to evaluate the effects of rice noodles (low FODMAPs) vs. wheat noodles (high FODMAPs) on typical GER symptoms, and the correlation between GERD symptoms and intestinal gas production. Results: Heartburn and regurgitation scores were highest in most patients (19/21) during the first 15 min after meals. At 15 min after lunch, wheat was significantly associated with more regurgitation and heartburn than rice. Also, at 15 min after breakfast, wheat aggravated more regurgitation than rice. Wheat ingestion was significantly associated with higher H2 and CH4 levels after lunch compared to rice, whereas gas levels before lunch were similar (p > 0.05). The area under the curve of H2 and CH4 concentration 15 min after a lunch of wheat moderately correlated with the regurgitation severity at 15-min (r = 0.56, p < 0.05). Conclusion: Wheat induced more GERD symptoms than rice in patients with overlapping GERD-IBS. This effect, immediately developed after lunch, was associated with more intestinal gas production. Thus, a low FODMAPs diet may relieve postprandial GERD symptoms in GERD patients with overlapping IBS. Wheat inducing more regurgitation than rice after breakfast suggests other mechanism(s) besides gut fermentation.

Evaluation of the efficacy of simethicone in the abdominal ultrasound and pancreas evaluation on dogs

ABSTRACTIntestinal gas results in low quality imaging in abdominal ultrasound in domestic animals. On dogs, suggested preparation protocols are varied and low studied. The aim of this work was comparing the efficacy between two preparations in improving the complete abdominal ultrasound exam and pancreas preview. 40 dogs were enrolled in this study. They were separated in two groups (NS diet: fasting; WS diet: fasting added to simethicone). The pancreas images were taken from left lateral decubitus. A score of one to three (1: bad, 2: fair and 3: good) measured separately the quality of the complete exam, left and right limbs and pancreatic body. In both treatments, there were results above 50% of good images of the complete exam and right limb of the pancreas. Otherwise, there were results above 90% of bad images of the right limb and pancreatic body. According to the fact of there is no statistically significant difference between the diets, as well submitted animals to the NS diet as the WS diet, all the results obtained from this work (bad or good images) could be acquired from any of both diets. The good abdominal exam preview as well submitted animals to the simethicone as those without the medication refute this medicine requirement to the abdominal ultrasound exam, but not to the evaluation of the left limb and pancreatic body.

Sulphur metabolism in colon cancer tissues: a case report and literature review

Sulphur-containing compounds have been linked to colorectal cancer by factors such as the presence of methyl mercaptan in intestinal gas and long-term dietary intake associated with sulphur-metabolizing microbiota. Therefore, this current case report hypothesized that active sulphur metabolism in colorectal cancer results in the formation of sulphur compounds in the intestine and, thus, examined sulphur metabolites possibly associated with sulphur respiration in colon cancer tissues. The patient was a 73-year-old female that underwent laparoscopic right hemicolectomy for ascending colon cancer. During the surgery, colon cancer tissues and normal intestinal mucosa samples were collected. After optimizing the sample concentrations for homogenization (pre-treatment), the samples were stabilized using a hydroxyphenyl-containing derivative and the relevant metabolites were quantified using liquid chromatography with tandem mass spectrometry. The results showed that cysteine persulfide and cysteine trisulfide levels were higher in colon cancer tissues than in normal mucosal tissues. Thus, sulphur metabolism, possibly sulphur respiration, is enhanced in colon cancer tissues.

Left Chest Pain: Possible Causes and What to Do?

Chest pain on the left side can be a sign of heart problems, so it is very common that when it appears, the person thinks they might be having a heart attack. However, this type of pain can also indicate less serious problems, such as excessive intestinal gas, reflux or an anxiety attack, for example. This article aims to carry out a brief review of the literature on the possible causes of pain from the left side of the chest.

INDIGENOUS KNOWLEDGE BASED TRADITIONAL MEDICINAL PRACTICES OF NORTHERN KERALA, INDIA

Objective: To explore, collect and identify the traditional medicinal practices of Northern kerala and the medicinal plants used by them Methods: Field survey was conducted among 22 villages of Payyannur Taluk, Structured and semi structured interviews with 15 traditional healers in the study area. The plant species commonly known in the local name, used to treat various diseases were collected and recorded. Results: In the present investigation it has been identified that, 96 medicinal plants belonging to 92 genera and 54 families are used for the treatment of snake bite, insect bite, rheumatism, cuts and wounds, skin diseases, cough, digestive problems, fever, diabetes, jaundice, diarrhoea, kidney stone, bone fracture, intestinal gas and menstrual problems. Among the 96 medicinal plants used by the traditional healers 46 were herbs, 14 were shrubs, 20 were trees, 7 were climbers, 8 were creepers and 1 epiphyte. The medicinal plants belonging to 54 families and Acanthaceae, Apocynaceae, Euphorbiaceae, Asteraceae, Lamiaceae and Orchidaceae were the families with more number of medicinal plants. Conclusion: Majority of people in developing countries rely on these traditional medicines. Many of these practices have not been identified and systematically recorded yet. This study has identified many rare and medicinally important plants and their medicinal values and this will benefit to the society as these medicinal plants are locally available.

Review on Phytochemicals and Pharmacological Studies of Allium cepa (Onion)

In present days, herbal medicines have gained importance with both medical and economic implications. Throughout the world raised concerns of quality, safety and efficacy. Onion has been valued as a food, medicinal plant since ancient times and widely cultivated. And known as “Queen of the kitchen”. Due to its flavor, aroma, unique taste, medicinal properties of its compound. And acts as food which provides a good amount of nutrients, immunity to the body, helps in treating high cholesterol, diabetes, joint disorders, digestive ailments, loss of appetite, gallbladder diseases, angina pectoris, high blood pressure, atherosclerosis, sore throat, asthma, bronchitis, cough, intestinal gas and intestinal worms as therapeutic agent. Different biological properties, such as, antioxidants, antiinflammatory, anti-cholesterol, antihypertensive, anti-cancer, anti-arthritic, anti-bacterial, bronchodilator, expectorant, antispasmodic, antiseptic, carminative, anti-coagulant, fibrinolytic, anti-helminthic, anti-platelet, hepatoprotective activity, anti-diabetic, anti-viral, cardiovascular protective, anti-microbial, neuro protective, anti-genotoxic and anti-mutagenic effect, anti-pyretic, analgesic, and various other biological activities. Wide spectrum of biological activities of onion makes it as a potential medicinal and therapeutic agent

A 5G-powered robot-assisted teleultrasound diagnostic system in an intensive care unit

Background Teleultrasound provides an effective solution to problems that arise from limited medical resources, a lack of local expertise, and scenarios where the risk of infection is high. This study aims to explore the feasibility of the application of a 5G-powered robot-assisted teleultrasound diagnostic system in an intensive care unit. Methods In this study, the robot-assisted teleultrasound diagnostic system MGIUS-R3 was used. Using 5G network technology, the doctor manipulates the robotic arm to perform teleultrasound examination. The doctor can adjust parameters via the teleultrasound control panel, and real-time transmission of audio, video and ultrasound images can facilitate simultaneous communication between both parties. All patients underwent robot-assisted teleultrasound examination and bedside ultrasound examination of the liver, gallbladder, pancreas, spleen, kidney, as well as assessment for pleural effusion and abdominal effusion. We evaluated the feasibility of the application of the robot-assisted teleultrasound diagnosis system in the intensive care unit in terms of consultation duration, image quality, and safety. We also compared diagnostic consistency and differences. Results Apart from one patient who was excluded due to severe intestinal gas interference and poor image quality, a total of 32 patients were included in this study. Every patient completed all relevant examinations. Among them, 20 patients were male; 12 were female. The average age of the patients was 61 ± 20 years. The average duration of teleultrasound diagnosis was 17 ± 7 min. Of the 32 patients, 26 had positive results, 6 had negative results, and 5 had inconsistent diagnoses. The overall diagnostic results were basically the same, and there were no differences in diagnostic levels between the two. The overall average image quality score was 4.73 points, which represented a high-quality image. After robot-assisted teleultrasound examination, no significant changes were observed in the vital signs of patients as compared to before examination, and no examination-related complications were found. Conclusion The 5G-powered robot-assisted teleultrasound diagnostic system was associated with the benefits of clear images, simple operation, relatively high levels of consistency in terms of diagnostic results, higher levels of safety, and has considerable application value in the intensive care unit.