scholarly journals The Correlations between Horizontal and Vertical Peripheral Refractions and Human Eye Shape Using Magnetic Resonance Imaging in Highly Myopic Eyes

Healthcare ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 966
Author(s):  
Hui-Ying Kuo ◽  
John Ching-Jen Hsiao ◽  
Jing-Jie Chen ◽  
Chi-Hung Lee ◽  
Chun-Chao Chuang ◽  
...  

The aim of this study was to determine the relationship between relative peripheral refraction and retinal shape by 2-D magnetic resonance imaging in high myopes. Thirty-five young adults aged 20 to 30 years participated in this study with 16 high myopes (spherical equivalent < −6.00 D) and 19 emmetropes (+0.50 to −0.50 D). An open field autorefractor was used to measure refractions from the center out to 60° in the horizontal meridian and out to around 20° in the vertical meridian, with a step of 3 degrees. Axial length was measured by using A-scan ultrasonography. In addition, images of axial, sagittal, and tangential sections were obtained using 2-D magnetic resonance imaging. The highly myopic group had a significantly relative peripheral hyperopic refraction and showed a prolate ocular shape compared to the emmetropic group. The highly myopic group had relative peripheral hyperopic refraction and showed a prolate ocular form. Significant differences in the ratios of height/axial (1.01 ± 0.02 vs. 0.94 ± 0.03) and width/axial (0.99 ± 0.17 vs. 0.93 ± 0.04) were found from the MRI images between the emmetropic and the highly myopic eyes (p < 0.001). There was a negative correlation between the retina’s curvature and relative peripheral refraction for both temporal (Pearson r = −0.459; p < 0.01) and nasal (Pearson r = −0.277; p = 0.011) retina. For the highly myopic eyes, the amount of peripheral hyperopic defocus is correlated to its ocular shape deformation. This could be the first study investigating the relationship between peripheral refraction and ocular dimension in high myopes, and it is hoped to provide useful knowledge of how the development of myopia changes human eye shape.

2021 ◽  
Vol 40 (2) ◽  
pp. 1-21
Author(s):  
Bohan Wang ◽  
George Matcuk ◽  
Jernej Barbič

We present a method for modeling solid objects undergoing large spatially varying and/or anisotropic strains, and use it to reconstruct human anatomy from medical images. Our novel shape deformation method uses plastic strains and the finite element method to successfully model shapes undergoing large and/or anisotropic strains, specified by sparse point constraints on the boundary of the object. We extensively compare our method to standard second-order shape deformation methods, variational methods, and surface-based methods, and demonstrate that our method avoids the spikiness, wiggliness, and other artifacts of previous methods. We demonstrate how to perform such shape deformation both for attached and un-attached (“free flying”) objects, using a novel method to solve linear systems with singular matrices with a known nullspace. Although our method is applicable to general large-strain shape deformation modeling, we use it to create personalized 3D triangle and volumetric meshes of human organs, based on magnetic resonance imaging or computed tomography scans. Given a medically accurate anatomy template of a generic individual, we optimize the geometry of the organ to match the magnetic resonance imaging or computed tomography scan of a specific individual. Our examples include human hand muscles, a liver, a hip bone, and a gluteus medius muscle (“hip abductor”).


Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 277
Author(s):  
Paolo Compagnucci ◽  
Giovanni Volpato ◽  
Umberto Falanga ◽  
Laura Cipolletta ◽  
Manuel Antonio Conti ◽  
...  

Myocardial inflammation is an important cause of cardiovascular morbidity and sudden cardiac death in athletes. The relationship between sports practice and myocardial inflammation is complex, and recent data from studies concerning cardiac magnetic resonance imaging and endomyocardial biopsy have substantially added to our understanding of the challenges encountered in the comprehensive care of athletes with myocarditis or inflammatory cardiomyopathy (ICM). In this review, we provide an overview of the current knowledge on the epidemiology, pathophysiology, diagnosis, and treatment of myocarditis, ICM, and myopericarditis/perimyocarditis in athletes, with a special emphasis on arrhythmias, patient-tailored therapies, and sports eligibility issues.


Author(s):  
Karen Perta ◽  
Eileen Kalmar ◽  
Youkyung Bae

Purpose The aim of the study was to update our information regarding the salpingopharyngeus (SP) muscle using cadaveric and in vivo magnetic resonance imaging (MRI) data. Primary objectives were to (a) observe the presence/absence of the muscle and (b) quantify and describe its dimensions and course. Method SP specimens from 19 cadavers (10 women, nine men) were analyzed. Following head bisection, measurements of SP, including width of the cartilaginous attachment (CW) and width of the superior muscle base (SMW), were taken before and after removal of the overlying mucosa. In addition, SP was analyzed in 15 healthy subjects (eight men, seven women) using high-resolution three-dimensional MRI data. CW and SMW measures were replicated in the paraxial MRI view. Results The presence of the salpingopharyngeal fold and muscle was confirmed bilaterally in all cadaveric and living subjects. Following mucosa removal, mean cadaveric CW and SMW measurements were 5.6 and 3.8 mm, respectively. Mean in vivo CW and SMW were 6.1 and 3.7 mm, respectively. Results from the hierarchical regression analyses revealed that, in both cadaveric and living groups, SMW is dependent on the relationship between age and body weight, after controlling for sex. Conclusions The salpingopharyngeal fold and SP muscle are always present bilaterally and can be quantified at the superior origin using both cadaveric and in vivo three-dimensional MRI data. Though both the superior origin and inferior course of SP are highly variable, the size of the SP muscle is dependent on characteristics known to affect muscle fibers, such as the relationship between age and body weight. Given the consistent and quantifiable presence of the SP muscle, its potential role in velopharyngeal function for speech and swallowing is reconsidered. Supplemental Material https://doi.org/10.23641/asha.14347859


2020 ◽  
Author(s):  
Jinmei Zheng ◽  
Bin Sun ◽  
Ruolan Lin ◽  
Yongqi Teng ◽  
Xihai Zhao ◽  
...  

Abstract Background Atherosclerotic plaques are often present in regions with complicated flow patterns. Vascular morphology plays a role in hemodynamics. In this study, we investigate the relationship between the geometry of the vertebrobasilar artery system and the basilar artery (BA) plaque prevalence.Methods We enrolled 290 patients with posterior circulation ischemic stroke. We distinguished four configurations of the vertebrobasilar artery: Walking, Tuning Fork, Lambda, and No Confluence. The diameter of the vertebral artery (VA) and the number of bends in the intracranial VA segment was assessed using three-dimensional time-of-flight magnetic resonance angiography. We differentiated between multi-bending (≥ 3 bends) and oligo-bending (< 3 bends) VAs. High-resolution magnetic resonance imaging was used to evaluate BA plaques. Logistic regression models examined the relationship between the geometry type and BA plaque prevalence.Results After adjusting for sex, age, body mass index ≥ 28, hypertension, and diabetes mellitus, the Walking, Lambda, and No Confluence geometries were associated with the presence of BA plaque. Patients with multi-bending VAs in both the Walking (71.43%, P = 0.003) and Lambda group (40.43%, P = 0.018) had more plaques compared to patients with oligo-bending VAs in these groups. In the Lambda group, the diameter difference between the VAs was larger in patients with BA plaques than that in patients without BA plaques (1.4 mm vs. 0.9 mm, P < 0.001).Conclusions The Walking, Lambda, and No Confluence geometry, ≥ 3 bends in the VAs, and a large diameter difference between the VAs were associated with the presence of BA plaque.


2021 ◽  
Vol 18 (4) ◽  
Author(s):  
Murat Bayav ◽  
Murat Sahin

Background: Anatomical variations in vascular structures are frequently encountered. In the cerebellopontine region, anatomical variations, especially variations in the anterior inferior cerebellar artery (AICA) in relation to cranial nerves passing through the internal acoustic canal (IAC), are common. Magnetic resonance imaging (MRI) provides detailed information for the evaluation of the cerebellopontine region and the IAC anatomy. Objectives: This study aimed to examine the relationship between the IAC anatomy and AICA loop variations and to investigate the frequency of anatomical variations and its correlation with demographic variables. Patients and Methods: In this study, 253 patients (age > 18 years), who underwent 3-Tesla MRI of the temporal bone between July 2019 and December 2019, were retrospectively evaluated. The exclusion criteria were images of poor diagnostic quality due to technical or patient-related reasons and the presence of a localized tumor that could disrupt the IAC. Four patients were excluded from the study because they had tumors related to IAC. The AICA variations were categorized according to the Chavda classification. The IAC size, canal diameter, canal length, and meatus width were measured, and the canals were characterized as cylindrical, funnel-shaped, and bud-shaped. Results: A total of 249 patients were included in this study. The Chavda type I vascular loop was the most common type on both sides. The mean size measurements of IACs were significantly higher in the group of vascular loops compared to the group without vascular loops. The presence of a vascular loop was significantly more common in funnel- and bud-shaped IACs compared to cylindrical IAC. Also, there was a negative correlation between the patient’s age and all IAC dimensions. Conclusion: The results of the present study showed that the AICA loop variations were closely related to the size and shape of the IAC.


Sign in / Sign up

Export Citation Format

Share Document